Some implications of linear-quadratic-linear radiation dose-response with regard to hypofractionation

Medical Physics

Volumn 35, Issue 9, 2008, Pages 4161-4172

  Astrahan, Melvin ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

BED; Biologically effective dose; Hypofractionation; Linear quadratic

Indexed keywords

DOSIMETRY; EXTRAPOLATION;

BIOLOGICALLY EFFECTIVE DOSE; CLINICAL EXPERIENCE; CONVENTIONAL FRACTIONATIONS; DOSE RESPONSE RELATIONSHIPS; DOSE-RESPONSE CURVES; HYPOFRACTIONATION; LINEAR QUADRATIC; TECHNOLOGICAL ADVANCES;

CURVE FITTING;

ANIMAL CELL; ARTICLE; CELL KILLING; CELL SURVIVAL; CONTROLLED STUDY; DOSIMETRY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION RESPONSE; SURVIVAL RATE;

EID: 50449090803     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.2969065     Document Type: Article

References (22)

1. H. Withers, " Biologic basis for altered fractionation schemes.," Cancer 55, 2086-2095 (1985).
2. E. Hall, " Cell survival curves.," in Radiobiology for the Radiologist, 5th ed. (Lippincott Williams & Wilkins, Philadelphia, 2000), pp. 35-37.
3. M. Elkind and H. Sutton, " X-ray damage and recovery in mammalian cells in culture.," Nature (London) 184, 1293-1295 (1959).
4. G. Barendsen, " Dose fractionation, dose rate and isoeffect relationships for normal tissue responses.," Int. J. Radiat. Oncol., Biol., Phys. 8, 1981-1997 (1982).
5. J. Fowler, " The linear-quadratic formula and progress in fractionated radiotherapy.," Br. J. Radiol. 62, 679-694 (1989).
6. B. Jones, L. Tan, and R. Dale, " Derivation of the optimum dose per fraction from the linear quadratic model.," Br. J. Radiol. 68, 894-902 (1995).
7. H. Thames, " Time-dose factors in radiotherapy, A review of the human data.," Radiother. Oncol. 19, 219-235 (1990).
8. J. Fowler, W. Tome, J. Fenwick, and M. Mehta, " A challenge to traditional radiation oncology.," Int. J. Radiat. Oncol., Biol., Phys. 60, 1241-1256 (2004).
9. L. Garcia, D. Wilkins, G. Raaphorst, " αβ ratio, a dose range dependence study.," Int. J. Radiat. Oncol., Biol., Phys. 67, 587-593 (2007).
10. M. Guerrero and X. Li, " Extending the linear-quadratic model for large fraction doses pertinent to stereotactic radiotherapy.," Phys. Med. Biol. 49, 4825-4835 (2004).
11. J. Z. Wang, N. A. Mayr, and W. T. C. Yu, " A generalized linear-quadratic formula for high-dose-rate brachytherapy and radiosurgery.," Int. J. Radiat. Oncol., Biol., Phys. 69, S619-S620 (2007).
12. C. Park, L. Papiez, S. Zhang, M. Story, and R. Timmerman, " The unifying (hybrid) survival curve and single fraction equivalent dose: Useful tools in understanding the potency of ablative radiation therapy.," Int. J. Radiat. Oncol., Biol., Phys. 70, 847-852 (2008).
13. K. Atwood and A. Norman, " On the interpretation of multi-hit survival curves.," Proc. Natl. Acad. Sci. U.S.A. 35, 696-709 (1949).
14. M. Carlone, D. Wilkins, and G. Raaphorst, " The modified linear quadratic model of Guerrero and Li can be derived from mechanistic basis and exhibits linear-quadratic-linear behavior.," Phys. Med. Biol. 50, L9-L15 (2005).
15. T. Puck and P. Markus, " Action of x-rays on mammalian cells.," J. Exp. Med. 103, 653-666 (1956).
16. H. Thames and H. Withers, " Test of equal effect per fraction and estimation of initial clonogen number in micro colony assays of survival after fractionated irradiation.," Br. J. Radiol. 53, 1071-1077 (1980).
17. A. Han, A. C. Hill, and M. Elkind, " Repair of cell killing and neoplastic transformation at reduced dose rates for Co60 γ -rays.," Cancer Res. 40, 3328-3332 (1980).
18. K. Stone, H. Wunderli, G. Mickey, and D. Paulson, " Isolation of a human prostate carcinoma cell line (DU-145).," Int. J. Cancer 21, 274-281 (1978).
19. J. Leith, " Radiobiological studies of PC-3 and DU-145 human prostate cancer cells, x-ray sensitivity in vitro and hypoxic fractions of xenografted tumors in vivo.," Int. J. Radiat. Oncol., Biol., Phys. 25, 283-287 (1993).
20. B. G. Douglas and J. F. Fowler, " The effect of multiple small doses of X-rays on skin reactions in the mouse and a basic interpretation.," Radiat. Res. 66, 401-426 (1976).
21. A. J. van der Kogel, " Spinal cord tolerance: Time-dose-isoeffect relationships.," in Late Effects of Radiation on the Spinal Cord, (Radiobiological Institute of the Organization for Health Research TNO, Rijswijk, The Netherlands, 1979), pp. 101-121.
22. D. Brenner, " Hypofractionation for prostate cancer radiotherapy-what are the issues?," Int. J. Radiat. Oncol., Biol., Phys. 57, 912-914 (2003).