11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 3, 2004, Pages 603-611

  Matarrese, Mario ^a   Salimbeni, Aldo ^b   Turolla, Elia Anna ^a   Turozzi, Damiano ^b   Moresco, Rosa Maria ^a   Poma, Davide ^b   Magni, Fulvio ^a   Todde, Sergio ^a   Rossetti, Claudio ^a   Sciarrone, Maria Teresa ^a   Bianchi, Giuseppe ^a   Kienle, Marzia Galli ^a   Fazio, Ferruccio ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b Lusochimica SpA   (Italy)

Author keywords

11C radioligand; ACE inhibitor; PET; Zofenoprilat

Indexed keywords

BENZOIC ACID DERIVATIVE; CARBON 11; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ZOFENOPRILAT; CAPTOPRIL; CARBON; DRUG DERIVATIVE; ZOFENOPRIL; ZOFENOPRILATE;

ACYLATION; ARTICLE; DRUG ACCUMULATION; DRUG DISTRIBUTION; GALLBLADDER; HEART; KIDNEY; LIVER; MICHAEL ADDITION; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; SYNTHESIS; TISSUE DISTRIBUTION; CHEMICAL STRUCTURE; CHEMISTRY; CLINICAL TRIAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; HUMAN; MALE; MIDDLE AGED;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CAPTOPRIL; CARBON RADIOISOTOPES; HUMANS; MALE; MIDDLE AGED; MOLECULAR STRUCTURE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 5044243195     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.10.054     Document Type: Article

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