Assessment of stem cell markers during long-term culture of mouse embryonic stem cells

Cytotechnology

Volumn 44, Issue 1-2, 2004, Pages 77-91

  Berrill, A ^a   Tan, H L ^a   Wuang, S C ^a   Fong, W J ^a   Choo, Andre B H ^a   Oh, Steve K W ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

Alkaline phosphatase; Leukaemia inhibitory factor; Oct 4; Pluripotency; SSEA 1; Stem cell culture

Indexed keywords

LEUKEMIA INHIBITORY FACTOR; OCTAMER TRANSCRIPTION FACTOR 4; STAGE SPECIFIC EMBRYO ANTIGEN 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BIOLOGICAL MONITORING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO CELL; ENZYME ACTIVITY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REDUCTION; STEM CELL; TISSUE TYPES;

ANIMALIA;

EID: 5044238030     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CYTO.0000043414.90681.c2     Document Type: Article

References (22)

1. Burdon T., Smith A. and Savatier P. 2002. Signaling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol. 12: 432-438.
2. Evans M.J. and Kaufman M.H. 1981. Establishment in culture of pluripotent cells from mouse embryos. Nature 292: 154-156.
3. Hahnel A.C., Rappolee D.A., Millan J.L., Manes T., Ziome C.A., Theodosiou N.G., Werb Z., Pedersen R. and Schultz G.A. 1990. Two alkaline phosphatase genes are expressed during early development in the mouse embryo. Development 110: 555-564.
4. Heinrich P.C., Behrmann I., Müller-Newen G., Schaper F. and Graeve L. 1998. Interleukin-6-type cytokine signaling through the gp130/Jak/STAT pathway. Biochem. J. 334: 297-314.
5. Ling V. and Neben S. 1997. In vitro differentiation of embryonic stem cells: immunophenotypic analysis of cultured embryoid bodies. J. Cell Physiol. 171: 104-115.
6. Livak K.J. and Schmittgen T.D. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C(T)) method. Methods 25: 402-408.
7. Martin G.R. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinomas stem cells. Proc. Natl. Acad. Sci. USA 78: 7634-7638.
8. Murray P. and Edgar D. 2001. The regulation of embryonic stem cell differentiation by leukaemia inhibitory factor. Differentiation 68: 227-234.
9. Nichols J., Zevnik B., Anastassiadis K., Niwa H., Klewe-Nebenius D., Chambers I., Schöler H. and Smith A. 1998. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95: 379-391.
10. Niwa H., Miyazaki J. and Smith A.G. 2000. Quantitative expression of Oct3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet 24: 372-376.
11. Oka M., Tagoku K., Russell T.L., Nakano Y., Hamazaki T., Meyer E.M., Yokota T. and Terada N. 2002. CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells. Mol. Biol. Cell 4: 1274-1281.
12. Pesce M. and Schöler H.R. 2001. Oct-4: Gatekeeper in the beginnings of mammalian development. Stem Cells 19: 271-278.
13. Rathjen P.D., Toth S., Willis A., Heath J.K. and Smith A.G. 1990. Differentiation inhibiting activity is produced in matrix associated and diffusible forms that are generated by alternate promoter usage. Cell 62: 1105-1114.
14. Schöler H.R. 1991. Octamania: the POU factors in murine development. Trends Genet. 7: 323-329.
15. Smith A.G., Heath J.K., Donaldson D.D., Wong G.G., Moreau J., Stall M. and Rogers D. 1988. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336: 688-690.
16. Solter D. and Knowles B.B. 1978. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc. Natl. Acad. Sci. USA 75: 5565-5569.
17. Viswanathan S., Benatar T., Rose-John S., Lauffenburger D.A. and Zandstra P.W. 2002. Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell self-renewal responses to LIF and HIL-6. Stem Cells 20: 119-138.
18. Williams M.A., Gross S.K., Evans J.E. and McCluer R.H. 1988a. Glycolipid stage-specific embryonic antigens (SSEA-1) in kidneys of male and female C57BL/6J and beige adult mice. J. Lipid Res. 29: 1613-1619.
19. Williams R.L., Hilton D.J., Pease S., Willson T.A., Stewart C.L., Gearing D.P., Wagner E.F., Metcalf D., Nicola N.A. and Gough N.M. 1988b. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336: 684-687.
20. +, ESC derived cells engraft and differentiate into hepatocytes in vivo. Stem Cells 20: 338-346.
21. Yoshida K., Chambers I., Nichols J., Smith A., Saito M., Yasukawa K., Shoyab M., Taga T. and Kishimoto T. 1994. Maintenance of the pluripotent phenotype of embryonic stem cells through direct activation of gp130 signalling pathways. Mech. Dev. 45: 163-171.
22. Zandstra P.W., Le H.V., Daley G.Q., Griffith L.G. and Lauffenburger D.A. 2000. Leukaemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. Biotechnol. Bioeng. 69: 607-617.