Early abnormalities in sciatic nerve function and structure in a rat model of Charcot-Marie-Tooth type 1A disease

Experimental Neurology

Volumn 190, Issue 1, 2004, Pages 213-223

  Grandis, Marina ^a   Leandri, Massimo ^a,b   Vigo, Tiziana ^a   Cilli, Michele ^b   Sereda, Michael W ^c,d   Gherardi, Gianfranco ^a   Benedetti, Luana ^a   Mancardi, Gianluigi ^a   Abbruzzese, Michele ^a   Nave, Klaus Armin ^c   Nobbio, Lucilla ^a,e   Schenone, Angelo ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e SWISS FEDERAL INSTITUTE OF TECHNOLOGY   (Switzerland)

Author keywords

Axonal atrophy; Charcot Marie Tooth type 1A; Demyelination; Experimental neurophysiology; Footprint analysis; Morphometry; Neurofilaments; Schwann cells; Sciatic nerve; Transgenic animals

Indexed keywords

MYELIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMYELINATION; ELECTROPHYSIOLOGY; HEMIZYGOSITY; HEREDITARY MOTOR SENSORY NEUROPATHY; LEG MUSCLE; MICROSCOPY; MOLECULAR BIOLOGY; MOTOR NERVE CONDUCTION; MUSCLE WEAKNESS; NERVE FIBER; NEUROFILAMENT; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SCIATIC NEUROPATHY; TOE; TRANSGENIC ANIMAL; WILD TYPE;

AGE FACTORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; BEHAVIOR, ANIMAL; CHARCOT-MARIE-TOOTH DISEASE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTROPHYSIOLOGY; GENETIC PREDISPOSITION TO DISEASE; MICE; MOTOR ACTIVITY; MUSCLE WEAKNESS; MYELIN PROTEINS; MYELIN SHEATH; NEURAL CONDUCTION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SCIATIC NERVE; SCIATIC NEUROPATHY;

EID: 5044236743     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.07.008     Document Type: Article

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