Differential inhibition of Scutellaria barbata D. Don (Lamiaceae) on HCG-promoted proliferation of cultured uterine leiomyomal and myometrial smooth muscle cells

Immunopharmacology and Immunotoxicology

Volumn 26, Issue 3, 2004, Pages 329-342

  Lee, Tae Kyun ^a   Kim, Dong I I ^a   Song, Young Lim ^a   Lee, Young Choon ^b   Kim, Hyung Min ^c   Kim, Cheorl Ho ^c,d  

^a Dongguk University   (South Korea)

^b Dong A University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Dongguk University   (South Korea)

Author keywords

Cell proliferation; HCG; HCG LH receptor; Leiomyoma; Scutellaria barbata D. Don (Lamiaceae); Uterus

Indexed keywords

CELL CYCLE PROTEIN; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN RECEPTOR; CYCLIN E; CYCLINE; LUTEINIZING HORMONE RECEPTOR; PLANT EXTRACT; PROTEIN CDC2; SCUTELLARIA BARBATA EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MITOSIS INHIBITION; MYOMETRIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCUTELLARIA; SCUTELLARIA BARBATA; SMOOTH MUSCLE FIBER; TUMOR CELL CULTURE; UTERUS MYOMA;

ACTINS; ADULT; CDC2 PROTEIN KINASE; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHORIONIC GONADOTROPIN; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; DRUGS, CHINESE HERBAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEIOMYOMA; MYOCYTES, SMOOTH MUSCLE; MYOMETRIUM; PROLIFERATING CELL NUCLEAR ANTIGEN; RHIZOME; SCUTELLARIA; TUMOR CELLS, CULTURED; UTERINE NEOPLASMS;

LAMIACEAE; LIA; SCUTELLARIA;

EID: 5044235806     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.1081/IPH-200026841     Document Type: Article

References (41)

1. Dictionary of Chinese Materia Medica. Science and Technology Press of Shanghai, Shanghai.; Jiangsu New Medical College, Ed.; Science and Technology Press of Shanghai: Shanghai, 1977.
2. Wong, B.Y.; Lau, B.H.; Jia, T.Y.; Wan, C.P. Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother. Radiopharm. 1996, 11, 51-56.
3. Han, F.; Hu, J.; Xu, H. Effects of some Chinese herbal medicine and green tea antagonizing mutagenesis caused by cigarette tar. Zhonghua Yu Fang Yi Xue Za Zhi. 1997, 31, 71-74.
4. Wong, B.Y.; Lau, B.H.; Yamasaki, T.; Teel, R.W. Inhibition of dexamethasone-induced cytochrome P450-mediated mutagenicity and metabolism of aflatoxin B1 by Chinese medicinal herbs. Eur. J. Cancer Prev. 1993, 2, 351-356.
5. Sato, Y.; Suzaki, S.; Nishikawa, T.; Kihara, M.; Shibata, H.; Higuti, T. Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus. J. Ethnopharmacol. 2000, 72, 438-483.
6. Zaloudek, C.; Norris, H.J. Mesenchymal tumors of the uterus. In Blaustein's Pathology of the Female Genital Tract, 4th Ed.; Kurman, R.J., Ed.; Springer-Verlag: NY, USA, 1994; 849-914.
7. Compel, C.; Silverberg, S.G. Pathology in Gynecology and Obstetrics; J.B. Lippincott Co.: PA, USA, 1992; 218-225.
8. Brandon, D.D.; Erickson, T.E.; Keenan, E.J.; Strawn, E.Y.; Novy, M.J.; Burry, K.A.; Warner, C.; Clinton, G.M. Estrogen receptor gene expression in human uterine leiomyomata. J. Clin. Endocrinol. Metab. 1995, 80, 1876-1881.
9. Buttram, V.C., Jr.; Reiter, R.C. Uterine leiomyomata etiology, symptomatology and management. Fertil. Steril. 1981, 36, 433-455.
10. Englund, K.; Blanck, A.; Gustavsson, I.; Lundkvist, U.; Sjoblom, P.; Norgren, A.; Lindblom, B. Sex steroid receptors in human myometrium and fibroids: changes during the menstrual cycle and gonadotropin-releasing hormone treatment. J. Clin. Endocrinol. Metab. 1998, 83, 4092-4096.
11. Andersen, J.; Barbieri, R.L. Abnormal gene expression in uterine leiomyomas. J. Soc. Gynecol. Invest. 1995, 3, 663-672.
12. Strawn, E.Y., Jr.; Novy, M.J.; Burry, K.A.; Bethea, C.L. Insulin-like growth factor 1 promotes leiomyoma cell growth in vitro. Am. J. Obstet. Gynecol. 1995, 172, 1837-1844.
13. Van der Ven, L.T.; Roholl, P.J.; Gloudemans, T.; Van Buul-Offers, S.C.; Welters, M.J.; Bladergroen, B.A.; Faber, J.A.; Sussenbach, J.S.; Den Otter, W. Expression of insulin-like growth factors (IGFs), their receptors and IGF binding protein-3 in normal, benign and malignant smooth muscle tissues. Br. J. Cancer 1997, 75, 1631-1640.
14. Horiuchi, A.; Nikaido, T.; Yoshizawa, T.; Ito, K.; Kobayashi, Y.; Toki, T.; Konishi, I.; Fujii, S. HCG promotes proliferation of uterine leiomyomal cells more strongly than that of myometrial smooth muscle cells in vitro. Mol. Human Reprod. 2000, 6, 523-528 2000.
15. Segaloff, D.L.; Ascoli, M. The lutropin/choriogonadotropin receptor. 4 Years later. Endocr. Rev. 1993, 14, 324-347.
16. Singh, M.; Zuo, J.; Li, X.; Ambrus, G.; Lei, Z.M.; Yussman, M.A.; Sanfilippo, J.S.; Rao, C.V. Decreased expression of functional human chorionic gonadotropin/luteinizing hormone receptor gene in human uterine leiomyomas. Biol. Reprod. 1995, 53, 591-597.
17. Zuo, J.; Lei, Z.M.; Rao, C.V. Human myometrial chorionic gonadotropin/luteinizing hormone receptors in preterm and term deliveries. J. Clin. Endocrinol. Metab. 1994, 79, 907-911.
18. Kounyei, J.L.; Lei, Z.M.; Rao, C.V. Human myometrial smooth muscle cells are novel targets of direct regulation by human chorionic gonadotropin. Biol. Reprod. 1993, 49, 1149-1157.
19. Nurse, P. Ordering S phase and M phase in the cell cycle. Cell 1994, 79, 547-550.
20. Sherr, C.J.; Roberts, J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 1995, 9, 1149-1163.
21. Noyes, R.W.; Hertig, A.T.; Rock, J. Dating the endometrial biopsy. Fertil. Steril. 1950, 1, 3-25.
22. Nowak, R.A.; Rein, M.S.; Heffner, L.J. Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors. J. Clin. Endocrinol. Metab. 1993, 76, 1308-1313.
23. Chomczynski, P.; Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987, 162, 156-159.
24. Minegishi, T.; Nakamura, K.; Takakura, Y.; Miyamoto, K.; Hasegawa, Y.; Ibuki, Y.; Igarashi, M.; Minegish, T. Cloning and sequencing of human LH/hCG receptor cDNA. Biochem. Biophys. Res. Commun. 1990, 172, 1049-1054.
25. Tsuda, T.; Watanabe, M.; Ohshima, K.; Norinobu, S.; Choi, S.W.; Kawakishi, S.; Osawa, T. Antioxidative activity of the anthocyanin pigments cyanidin 3-O- -D-Glucoside and cyanidin. J. Agric. Food Chem. 1994, 42, 2407-2410.
26. Ruch, R.J.; Cheng, S.J.; Klaunig, J.E. Prevention of cytotoxicity and inhibition of intracellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 1989, 10, 1003-1008.
27. Zee-Cheng, R.K. Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. Methods Find Exp. Clin. Pharmacol. 1992, 14, 725-736.
28. Oka, H.; Yamamoto, S.; Kuroki, T.; Harihara, S.; Marumo, T.; Kim, S.R.; Monna, T.; Kobayashi, K.; Tango, T. Prospective study of chemoprevention of hepatocellular carcinoma with Sho-saiko-to (TJ-9). Cancer 1995, 76, 743-749.
29. Yano, H.; Mizoguchi, A.; Fukuda, K.; Haramaki, M.; Ogasawara, S.; Momosaki, S.; Kojiro, M. The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase. Cancer Res. 1994, 54, 448-454.
30. Meng, Z.Y.; Zhang, J.Y.; Xu, S.X.; Sugahara, K. Steroidal saponins from Anemarrhena asphodeloides and their effects on superoxide generation. Planta Med. 1999, 65, 661-663.
31. Wong, B.Y.; Lau, B.H.; Teel, R.W. Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. Cancer Lett. 1992, 62, 123-131.
32. Wong, B.Y.; Lau, B.H.; Tadi, P.P.; Teel, R.W. Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of aflatoxin B1. Mutat Res. 1992, 279, 209-216.
33. Reshef, E.; Lei, Z.M.; Rao, C.V.; Pridham, D.D.; Chegini, N.; Luborsky, J.L. The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes, and decidua. J. Clin. Endocrinol. Metab. 1990, 70, 421-430.
34. Toth, P.; Li, X.; Lei, Z.M. Expression of human chorionic gonadotropin (hCG)/ luteinizing hormone receptors and regulation of the cyclooxygenase-1 gene by exogenous hCG in human fetal membranes. J. Clin. Endocrinol. Metab. 1996, 87, 1283-1288.
35. Lei, Z.M.; Toth, P.; Rao, C.V. Novel coexpression of human chorionic gonadotropin (hCG)/human luteinizing hormone receptors and their ligand hCG in human fallopian tubes. J. Clin. Endocrinol. Metab. 1993, 77, 863-872.
36. Rao, C.V.; Li, X.; Toth, P. Novel expression of functional human chorionic gonadotropin/luteinizing hormone receptor gene in human umbilical cords. J. Clin. Endocrinol. Metab. 1993, 77, 1706-1714.
37. Toth, P.; Li, X.; Rao, C.V. Expression of functional human chorionic gonadotropin/human luteinizing hormone receptor gene in human uterine arteries. J. Clin. Endocrinol. Metab. 1994, 79, 307-315.
38. Lincoln, S.R.; Lei, Z.M.; Rao, C.V.; Yussman, M.A. The expression of human chorionic gonadotropin/human luteinizing hormone receptors in ectopic human endometrial implants. J. Clin. Endocrinol. Metab. 1992, 75, 1140-1144.
39. Lei, Z.M.; Rao, C.V.; Lincoln, S.R.; Ackermann, D.M. Increased expression of human chorionic gonadotropin/human luteinizing hormone receptors in adenomyosis. J. Clin. Endocrinol. Metab. 1993, 76, 763-768.
40. Lin, J.; Lei, Z.M.; Lojun, S.; Rao, C.V.; Satyaswaroop, P.G.; Day, T.G. Increased expression of luteinizing hormone/human chorionic gonadotropin receptor gene in human endometrial carcinomas. J. Clin. Endocrinol. Metab. 1994, 79, 1483-1491.
41. Mandai, M.; Konishi, I.; Kuroda, H.; Fukumoto, M.; Komatsu, T.; Yamamoto, S.; Nanbu, K.; Rao, C.V.; Mori, T. Messenger ribonucleic acid expression of LH/hCG receptor gene in human ovarian carcinomas. Eur. J. Cancer 1997, 33, 1501-1507.