Lymphatic vessel density and prognosis in cutaneous melanoma [2]

British Journal of Cancer

Volumn 91, Issue 6, 2004, Pages 1224-1225

  Straume, O ^a   Akslen, L A ^a  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN D;

ANGIOGENESIS; BLOOD VESSEL PARAMETERS; HUMAN; LETTER; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPHATIC VESSEL DENSITY; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MELANOMA; MICROVASCULATURE; PRIORITY JOURNAL; PROGNOSIS; SKIN CANCER;

HUMANS; LYMPH NODES; LYMPHANGIOGENESIS; MELANOMA; PROGNOSIS; SKIN NEOPLASMS; SURVIVAL ANALYSIS;

EID: 5044226377     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602122     Document Type: Letter

References (15)

1. Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA (1998) Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci USA 95: 548-553
2. Akishima Y, Ito K, Zhang L, Ishikawa Y, Orikasa H, Kiguchi H, Akasaka Y, Komiyama K, Ishii T (2004) Immunohistochemical detection of human small lymphatic vessels under normal and pathological conditions using the LYVE-1 antibody. Virchows Arch 444: 153-157
3. Birner P, Schindl M, Obermair A, Breitenecker G, Kowalski H, Oberhuber G (2001) Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer. Int J Cancer 95: 29-33
4. Dadras SS, Paul T, Bertoncini J, Brown LF, Muzikansky A, Jackson DG, Ellwanger U, Garbe C, Mihm MC, Detmar M (2003) Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival. Am J Pathol 162: 1951-1960
5. Hlatky L, Hahnfeldt P, Folkman J (2002) Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 94: 883-893
6. Kaipainen A, Korhonen J, Mustonen T, van Hinsbergh VW, Fang GH, Dumont D, Breitman M, Alitalo K (1995) Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 92: 3566-3570
7. Padera TP, Boucher Y, Jain RK (2003) Correspondence re: S. Maula et al, intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Cancer Res. 63: 1920-1926, (Cancer Res 63: 8555-8556; author reply 8558)
8. Padera TP, Boucher Y, Jain RK (2003) Correspondence re: S. Maula et al, intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Cancer Res. 63: 1920-1926, (Cancer Res 63: 8555-8556; author reply 8558)
9. Shields JD, Borsetti M, Rigby H, Harper SJ, Mortimer PS, Levick JR, Orlando A, Bates DO (2004) Lymphatic density and metastatic spread in human malignant melanoma. Br J Cancer 90: 693-700
10. Simon R, Altman DG (1994) Statistical aspects of prognostic factor studies in oncology. Br J Cancer 69: 979-985
11. Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M (2001) Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 7: 192-198
12. Stacker SA, Caesar C, Baldwin ME, Thornton GE, Williams RA, Prevo R, Jackson DG, Nishikawa Si S, Kubo H, Achen MG (2001) VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 7: 186-191
13. Straume O, Jackson DG, Akslen LA (2003) Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma. Clin Cancer Res 9: 250-256
14. Valencak J, Heere-Ress E, Kopp T, Schoppmann SF, Kittler H, Pehamberger H (2004) Selective immunohistochemical staining shows significant prognostic influence of lymphatic and blood vessels in patients with malignant melanoma. Eur J Cancer 40: 358-364
15. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med 324: 1-8