Circulating levels of inhibin A, inhibin B and activin a in normal and intrauterine growth restricted (IUGR) fetuses

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 117, Issue 1, 2004, Pages 38-44

  Morpurgo, P S ^a   Cetin, I ^b   Borgato, S ^a   Cortelazzi, D ^a   Nobile Desantis, M S ^b   Vaghi, I ^a   Beck Peccoz, P ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Activin A; Fetus; Inhibin A; Inhibin B; Placenta

Indexed keywords

ACTIVIN A; GONADOTROPIN; INHIBIN A; INHIBIN B;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EVALUATION; FEMALE; FETUS; GENDER; GESTATIONAL AGE; HORMONE BLOOD LEVEL; HUMAN; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; INTRAUTERINE GROWTH RETARDATION; MALE; OBSERVATION; PRENATAL GROWTH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX;

EID: 5044225290     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2004.02.030     Document Type: Article

References (39)

1. Vale W., Rivier J., Vaughan J., McClintok R., Corrigan A., Woo W., et al. Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature. 321:1986;776-779
2. Vale W., Rivier J., Hsueh A. Chemical and biological characterization of the inhibin family of protein hormones. Recent Prog. Horm. Res. 44:1988;1-34
3. Scwall R., Schmelzer C.H., Matsuyama E., Mason A.J. Multiple actions of recombinant activin-A in vivo. Endocrinology. 125:1989;1420-1423
4. Matthews L.S., Vale W.W. Molecular and functional characterization of activin receptors. Receptor. 3:1993;313-319
5. Lebrun J.J., Vale W.W. Activin and Inhibin have antagonistic effects on ligand-dependent heterodimerization of the type I and II activin receptor and human erythroid differentiation. Mol. Cell Biol. 17:1997;1682-1691
6. Lewis K.A., Gray P.C., Blount A.L., MacConell L.A., Wlater E., Vale W. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 404:2000;411-414
7. Muttukrishna S., George L., Fowler P.A., Groome N.P., Knight P.G. Measurement of serum concentrations of inhibin-A (α-βA dimer) during human pregnancy. Clin Endocrinol. 42:1995;391-397
8. Muttukrishna S., Fowler P.A., George L., Groome N.P., Knight P.G. Serum concentrations of total activin A during the human menstrual cycle and pregnancy. J. Clin. Endocrinol. Metab. 81:1996;1471-1475
9. Petraglia F., Luisi S., Benedetto C., Zonca M., Florio P., Casarosa E., et al. Changes of dimeric Inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases. J. Clin. Endocrinol. Metab. 82:1997;2991-2995
10. Birdsall M., Ledger W.L., Groome N.P., Abdalla H., Muttukrishna S. Inhibin A and activin A in the first trimester of human pregnancy. J. Clin. Endocrinol. Metab. 82:1997;1557-1560
11. Meunier H., Rivier C., Evans R.M., Vale W. Gonadal and extragonadal expression of inhibin α,βA and βB subunits in various tissues predicts diverse functions. Proc. Natl. Acad. Sci USA. 85:1988;247-251
12. Minami S., Yamoto M., Nakano R. Immunoistochemical localization of inhibin/activin subunits in human placenta. Obstet. Gynecol. 80:1992;410-414
13. Petraglia F., Sawchenko P., Lim A.T.W., Rivier J., Vale W. Localization, secretion, and action of inhibin in human placenta. Science. 237:1987;187-189
14. Petraglia F., Calza L., Garuti G.C., Abrate M., Giardino L., Gennazzani A.R., et al. Presence and synthesis of inhibin subunits in human decidua. J. Clin. Endocrinol. Metab. 71:1990;487-492
15. Wallace E.M., Riley S.C., Crossley J.A., Ritoe A.C., Horne A., Shade M., et al. Dimeric inhibins in amniotic fluid, maternal serum, and fetal serum in human pregnancy. J. Clin. Endocrinol. Metab. 82:1997;218-222
16. DeBieve F., Beerlandt S., Hubinont C., Thomas K. Gonadotropins, prolactin, inhibin A, inhibin B, and activin A in human fetal serum from midpregnancy and term pregnancy. J. Clin. Endocrinol. Metab. 85:2000;270-274
17. Florio P., Benedetto C., Luisi S., Santuz M., Di Carlo C., Marozio L., et al. inhibin B and parturition: changes of maternal and cord levels according to the mode of delivery. Br. J. Obstet. Gynaecol. 106:1999;1061-1065
18. Resnik R. Intrauterine growth restriction. Obstet. Gynecol. 99:2002;490-496
19. Cetin I., Redaelli T., Taricco E., Giovannini N., Alvino G., Pardi G. The endocrine and metabolic profile of the growth retarded fetus. J. Pediatr. Endocr. Met. 14:2001;1497-1505
20. Arosio M., Cortelazzi D., Persani L., Palmieri E., Casati G., Baggiani A.M., et al. Circulating levels of growth hormone, insulin-like growth factor-I and prolactin in normal, growth retarded and anencephalic human fetuses. J. Endocrinol. Invest. 18:2001;346-353
21. Cetin I., Morpurgo P.S., Radaelli T., Taricco E., Cortelazzi D., Bellotti M., et al. Fetal plasma leptin concentrations (1995) relationship with different intrauterine growth patterns from 19 weeks to term. Pediatr. Res. 48:2000;646-6451
22. Parazzini F., Cortinovis I., Bortolus R., Fedele L. Standard di peso alla nascita in Italia. Ann. Ost. Gin. Med. Perin. CXII:1991;203-246
23. Todros T., Ferrazzi E., Groli C., Nicolini U., Parodi L., Pavoni M., et al. Fitting growth curves to head and abdomen measurements of the fetus: a multicentric study. J. Clin. Ultrasound. 15:1987;95-105
24. Marconi A.M., Cetin I., Buscaglia M., Pardi G. Midgestation cord sampling: what have we learned. Placenta. 13:1992;115-122
25. Pardi G., Cetin I., Marconi A.M., Lanfranchi A., Bozzetti P., Ferrazzi E., et al. Diagnostic value of blood sampling in fetuses with growth retardation. N. Engl. J. Med. 328:1998;692-696
26. Gosling RG, King DH. Continuous wave ultrasound as an alternative and complement to X-rays in vascular examinations. In: Reneman R.S. (Ed.), Cardiovascular applications of ultrasound. Amsterdam: North Holland; 1974. p. 266-82.
27. Daffos F., Cappella-Pavlovsky M., Forestier F. A new procedure for fetal blood sampling in utero: preliminary results of fifty tree cases. Am. J. Obstet. Gynecol. 146:1983;985-987
28. Andersson A.-M., Toppari J., Haavisto A.-M., Petersen J.H., Simell T., Simell O., et al. Longitudinal reproductive hormones profiles in infant: peak of inhibin B levels in infant boys exceed levels in adults men. J. Clin. Endocrinol. Metab. 83:1998;675-681
29. Loria P., Petraglia F., Concari M., Bertolotti M., Martella P., Luisi S., et al. Influence of age and sex on serum concentrations of total dimeric activin A. Eur. J. Endocrinol. 139:1998;487-492
30. Baccarelli A., Morpurgo P.S., Corsi A., Vaghi I., Fanelli M., Cremonesi G., et al. Activin A serum levels and aging of the pituitary-gonadal axis: a cross-sectional study in middle-aged and elderly healthy subjects. Exp. Gerontol. 36:2001;1403-1412
31. Tuuri T., Erämaa M., Hildén K., Ritvos O. The tissue distribution of Activin βA- and βB-subunit and follistatin messenger ribonucleic acids suggest multiple sites of action for the Activin-Follistatin system during human development. J. Clin. Endocrinol. Metab. 78:1994;1521-1524
32. Majdic G., McNeilly A.S., Sharpe R.M., Evans L.R., Groome N.P., Saunders P. Testicular expression of Inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat. J. Clin. Endocrinol. Metab. 138:1997;2136-2147
33. Beck-Peccoz P., Padmanabhan V., Baggiani A.M., Cortelazzi D., Buscaglia M., Medri G., et al. Maturation of hypothalamic-pituitary-gonadal function in normal human fetuses: circulating levels of gonadotropins, their common á-subunit and free testosterone, and discrepancies between immunological and biological activities of circulating follicle-stimulating hormone. J. Clin. Endocrinol. Metab. 73:1991;525-532
34. Hagen C., McNeilly A.S. The gonadotropin and their subunits in the foetal pituitary glands and circulation. J. Steroid Biochem. 8:1977;537-543
35. Clements J.A., Reyes F.I., Winter J.S.D., Faiman C. Studies on human sexual development. Fetal pituitary and serum, and amniotic concentrations of LH. CG and FSH. J. Clin. Endocrinol. Metab. 42:1976;9-19
36. Fuukui A., Asahima M. Control of cell differentiation and morphogenesis in amphibian development. Int. J. Develop. Biol. 38:1994;257-266
37. Bobrow C.S., Holmes R.P., Muttukrishna S., Mohan A., Groome N., Murphy D.J., et al. Maternal serum activin A, inhibin A, and follistatin in pregnancies with appropriately grown and small-for-gestational-age fetuses classified by umbilical artery Doppler ultrasound. Am. J. Obstet. Gynecol. 186(2):2002;283-287
38. Keelan J.A., Taylor R., Schellenberg J.C., Groome N.P., Mitchell M.D., North R.A. Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies. Obstet. Gynecol. 99(2):2002;267-274
39. Harada K., Shintani Y., Sakamoto Y., Wakatsuki M., Shitsukawa K., Saito S. Serum immunoreactive activin A levels in normal subjects and patients with various diseases. J. Clin. Endocrinol. Metab. 81:1996;2125-2130