Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

Journal of Pathology

Volumn 204, Issue 2, 2004, Pages 183-192

  Nagtegaal, Iris ^a,b   Gaspar, Claudia ^a   Marijnen, Corrie ^a   van de Velde, Cornelis ^a   Fodde, Riccardo ^a   van Krieken, Han ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Adenocarcinoma; Mucinous carcinoma; Radiotherapy; Rectal carcinoma

Indexed keywords

DNA; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; PROTEIN P21; PROTEIN P53;

ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL STRUCTURE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ACTIVITY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MEDICAL ASSESSMENT; MUCINOUS CARCINOMA; PREDICTION; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; RECTUM BIOPSY; RECTUM CARCINOMA; RECTUM SURGERY; TREATMENT OUTCOME;

ADENOCARCINOMA, MUCINOUS; APOPTOSIS; CELL CYCLE PROTEINS; COHORT STUDIES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MUCINS; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RECTAL NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 5044225097     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1621     Document Type: Article

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