Treatment results and prognostic factors in ewing sarcoma

Pediatric Hematology and Oncology

Volumn 21, Issue 7, 2004, Pages 597-610

  Kutluk, M Tezer ^a   Yalçin, Bilgehan ^a   Akyüz, Canan ^a   Varan, Ali ^a   Ruacan, Şevket ^a   Büyükpamukçu, M̈nevver ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Ewing sarcoma; Prognostic factors; Treatment

Indexed keywords

ANTHRACYCLINE; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; EPIRUBICIN; IFOSFAMIDE; VINCRISTINE;

ADOLESCENT; ADULT; ARTICLE; CARDIOTOXICITY; CHILD; CONTROLLED STUDY; COUGHING; DROWSINESS; EWING SARCOMA; FEMALE; HUMAN; HYPEREMIA; LIMB TUMOR; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; METASTASIS; PAIN; PARAPLEGIA; PARESTHESIA; PATHOLOGIC FRACTURE; PELVIS; PROGNOSIS; RECURRENT DISEASE; RESPIRATORY DISTRESS; SKULL; SURVIVAL RATE; THORAX PAIN; TREATMENT OUTCOME; TRUNK; TUMOR LOCALIZATION; URINE INCONTINENCE; URINE RETENTION;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; RECURRENCE; RETROSPECTIVE STUDIES; SARCOMA, EWING'S; SURVIVAL ANALYSIS;

EID: 5044220257     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.1080/08880010490501006     Document Type: Article

References (37)

1. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
2. Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br J Cancer. 1977;35:1-38.
3. Cox DR. Regression models and life tables. J R Statist Soc B. 1972;34:187-220.
4. Ahrens S, Hoffmann C, Jabar S, et al. Evaluation of prognostic factors in a tumor volume-adapted treatment strategy for localized Ewing sarcoma of bone: the CESS 86 experience. Cooperative Ewing Sarcoma Study. Med Pediatr Oncol. 1999;32:186-195.
5. Arai Y, Kun LE, Brooks T, et al. Ewing's sarcoma: local tumor control and patterns of failure following limited-volume radiation therapy. Int J Radiat Oncol Biol Phys. 1991;21:1501-1508.
6. Bacci G, Picci P, Ferrari S, et al. Neoadjuvant chemotherapy for Ewing's sarcoma of bone: no benefit observed after adding ifosfamide and etoposide to vincristine, actinomycin, cyclophosphamide, and doxorubicin in the maintenance phase - results of two sequential studies. Cancer. 1998;82:1174-1183.
7. Craft A, Cotterill S, Malcolm A, et al. Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study. J Clin Oncol. 1998;16:3628-3633.
8. Jenkin RD, Al-Fawaz I, Al-Shabanah MO, et al. Localized Ewing sarcoma/PNET of bone: prognostic factors and international data comparison. Med Pediatr Oncol. 2002;39:586-593.
9. Rosito P, Mancini FA, Rondelli R, et al. Italian Cooperative Study for the treatment of children and young adults with localized Ewing sarcoma of bone: a preliminary report of 6 years of experience. Cancer. 1999;86:421-428.
10. Sluga M, Windhager R, Lang S, et al. A long-term review of the treatment of patients with Ewing's sarcoma in one institution. Eur J Surg Oncol. 2001;27:569-573.
11. Wexler LH, DeLaney TF, Tsokos M, et al. Ifosfamide and etoposide plus vincristine, doxorubicin, and cyclophosphamide for newly diagnosed Ewing's sarcoma family of tumors. Cancer. 1996;78:901-911.
12. Cardenas-Cardos R, Rivera-Luna R, Lopez-Facundo NA, et al. Ewing's sarcoma: prognosis and survival in Mexican children from a single institution. Pediatr Hematol Oncol. 1999;16:519-523.
13. Villarroel M, Tordecilla J, Salgado C, et al. Multimodal therapy for children and adolescents with Ewing sarcoma: results of the First National Chilean Trial (1986-1991). Med Pediatr Oncol. 1997;29:190-196.
14. Cotterill SJ, Ahrens S, Paulussen M, et al. Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group. J Clin Oncol. 2000;18:3108-3114.
15. Oberlin O, Deley MC, Bui BN, et al. Prognostic factors in localized Ewing's tumours and peripheral neuroectodermal tumours: the third study of the French Society of Paediatric Oncology (EW88 study). Br J Cancer. 2001;85:1646-1654.
16. Ginsberg JP, Woo SY, Johnson ME, et al. Ewing's sarcoma family of tumors: Ewing's sarcoma of bone and soft tissue and the peripheral primitive neuroectodermal tumors. In: Pizzo PA, Poplack DG, eds. Principles and Practice of Pediatric Oncology. Philadelphia: Lippincott Williams & Wilkins; 2002:973-1016.
17. Pollock BH, Krischer JP, Vietti TJ. Interval between symptom onset and diagnosis of pediatric solid tumors. J Pediatr. 1991;119:725-732.
18. Widhe B, Widhe T. Initial symptoms and clinical features in osteosarcoma and Ewing sarcoma. J Bone Joint Surg Am. 2000;82:667-674.
19. Craft AW, Cotterill SJ, Bullimore JA, Pearson D. Long-term results from the first UKCCSG Ewing's Tumour Study (ET-1). United Kingdom Children's Cancer Study Group (UKCCSG) and the Medical Research Council Bone Sarcoma Working Party. Eur J Cancer. 1997;33:1061-1069.
20. Patricio MB, Vilhena M, Neves M, et al. Ewing's sarcoma in children: twenty-five years of experience at the Instituto Portuges de Oncologia de Francisco Gentil (I.P.O.F.G.). J Surg Oncol. 1991;47:37-40.
21. Pritchard DJ, Dahlin DC, Dauphine RT, et al. Ewing's sarcoma: a clinicopathological and statistical analysis of patients surviving five years or longer. J Bone Joint Surg. 1975;57-A:10-16.
22. Wilkins RM, Pritchard DJ, BurgertEO Jr, Unni KK. Ewing's sarcoma of bone: experience with 140 patients. Cancer. 1986;58:2551-2555.
23. Mirra JM, Picci P. Ewing's sarcoma. In: Mirra JM, Picci P, Gold HR, eds. Bone tumors: Clinical, Radiologic and Pathologic Correlations. Philadelphia: Lea & Febiger; 1989:1089-1116.
24. Bacci G, Ferrari S, Bertoni F, et al. Prognostic factors in nonmetastatic Ewing's sarcoma of bone treated with adjuvant chemotherapy: analysis of 359 patients at the Istituto Ortopedico Rizzoli. J Clin Oncol. 2000;18:4-11.
25. Burgert O, Nesbit ME, Garnsey LA, et al. Multimodal therapy for the management of non-pelvic, localized Ewing's sarcoma of bone: intergroup study IESS-II. J Clin Oncol. 1990;8:1514-1524.
26. Nesbit ME, Gehan EA, Burgert OE, et al. Multimodal therapy for the management of primary, non-metastatic Ewing's sarcoma of bone: a long-term follow-up of the First Intergroup study. J Clin Oncol. 1990;8:1664-1674.
27. Vlasak R, Sim FH. Ewing's sarcoma. Orthop Clin North Am. 1996;27:591-603.
28. Jenkin RD, Al-Fawaz I, Al-Shabanah MO, et al. Metastatic Ewing sarcoma/PNET of bone at diagnosis: prognostic factors-a report from Saudi Arabia. Med Pediatr Oncol. 2001;37:383-389.
29. Paulussen M, Ahrens S, Burdach S, et al. Primary metastatic (stage IV) Ewing tumor: survival analysis of 171 patients from the EICESS studies. European Intergroup Cooperative Ewing Sarcoma Studies. Ann Oncol. 1998;9:275-281.
30. Kinsella TJ, Miser JS, Waller B, et al. Long-term follow-up of Ewing's sarcoma of bone treated with combined modality therapy. Int J Radiat Oncol Biol Phys. 1991;20:389-395.
31. Cangir A, Vietti T, Gehan EA, et al. Ewing's sarcoma metastatic at diagnosis: results and comparisons of two intergroup Ewing's sarcoma studies. Cancer. 1990;66:887-893.
32. Sandoval C, Meyer WH, Parham DM, et al. Outcome in 43 children presenting with metastatic Ewing sarcoma: the St. Jude Children's Research Hospital experience, 1962 to 1992. Med Pediatr Oncol. 1996;26:180-185.
33. Barbieri E, Emiliani E, Zini G, et al. Combined therapy of localized Ewing's sarcoma of bone: analysis of results in 100 patients. Int J Radiat Oncol Biol Phys. 1990;19:1165-1170.
34. Shankar AG, Pinkerton CR, Atra A, et al. Local therapy and other factors influencing site of relapse in patients with localised Ewing's sarcoma. United Kingdom Children's Cancer Study Group (UKCCSG). Eur J Cancer. 1999;35:1698-1704.
35. Paulussen M, Ahrens S, Dunst J, et al. Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86. J Clin Oncol. 2001;19:1818-1829.
36. Delepine N, Delepine G, Cornille H, et al. Prognostic factors in patients with localized Ewing's sarcoma: the effect on survival of actual received drug dose intensity and of histologic response to induction therapy. J Chemother. 1997;9:352-363.
37. Kissane JM, Askin FB, Foulkes M, et al. Ewing's sarcoma of bone: clinicopathologic aspects of 303 cases from the Intergroup Ewing's Sarcoma Study. Hum Pathol. 1983;14:773-779.