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Volumn 14, Issue 10, 2008, Pages 937-947
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Molecular docking guided 3D-QSAR CoMFA analysis of N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of leukocyte-specific protein tyrosine kinase
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Author keywords
CoMFA; Lck; Leukocyte specific protein tyrosine kinase; QSAR
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Indexed keywords
N 4 PYRIMIDINYL 1H INDAZOL 4 AMINE INHIBITOR;
PROTEIN TYROSINE KINASE;
PROTEIN TYROSINE KINASE INHIBITOR;
ARTICLE;
BINDING SITE;
BIOLOGICAL ACTIVITY;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
CONTROLLED STUDY;
CORRELATION COEFFICIENT;
DRUG MECHANISM;
DRUG POTENCY;
DRUG STRUCTURE;
ENZYME INHIBITION;
LEUKOCYTE;
MOLECULAR DOCKING;
MOLECULAR MODEL;
PREDICTIVE VALIDITY;
PRIORITY JOURNAL;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
ANILINE COMPOUNDS;
BINDING SITES;
COMPUTER-AIDED DESIGN;
DRUG DESIGN;
HUMANS;
INDAZOLES;
INHIBITORY CONCENTRATION 50;
LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK);
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
PYRIMIDINES;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 50349095557
PISSN: 16102940
EISSN: 09485023
Source Type: Journal
DOI: 10.1007/s00894-008-0334-8 Document Type: Article |
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Times cited : (5)
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References (23)
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