Glucantime® reaction with fatal outcome following treatment of cutaneous leishmaniasis;Réaction à l'antimoniate de méglumine (Glucantime®) d'évolution fatale lors du traitement d'une leishmaniose cutanée

Annales de Dermatologie et de Venereologie

Volumn 135, Issue 4, 2008, Pages 317-318

  Hajlaoui, K ^a   Zeglaoui, F ^a   Ezzine, N ^a   Kastalli, S ^b   Elfekih, N ^a   Fazaa, B ^a   Loueslati, M H ^b   Kamoun, M R ^a  

^a CHARLES NICOLLE HOSPITAL   (Tunisia)

^b Centre National de Pharmacovigilance   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; MEGLUMINE ANTIMONATE; ANTIPROTOZOAL AGENT; MEGLUMINE; MEGLUMINE ANTIMONIATE; ORGANOMETALLIC COMPOUND;

AGED; CASE REPORT; DIZZINESS; ECCHYMOSIS; FEMALE; FEVER; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPOTENSION; LETTER; LEUKOCYTE COUNT; MEGALOCYTOSIS; MYALGIA; PANCYTOPENIA; SKIN LEISHMANIASIS; TREATMENT OUTCOME; FATALITY;

AGED; ANTIPROTOZOAL AGENTS; FATAL OUTCOME; FEMALE; HUMANS; LEISHMANIASIS, CUTANEOUS; MEGLUMINE; ORGANOMETALLIC COMPOUNDS;

EID: 50349095405     PISSN: 01519638     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annder.2007.10.003     Document Type: Letter

References (8)

1. Bégaud B., Evreux J.C., Jouglard J., and Lagier G. Imputabilité des effets inattendus ou toxiques des médicaments. Therapie 40 (1985) 111-118
2. Buffet P., Caumes E., and Gentilini M. Traitement des leishmanioses cutanées localisées. Ann Dermatol Venereol 121 (1994) 503-511
3. Pradinaud R. Leishmaniose cutanée. In: Dubertret L., et al. (Ed). Thérapeutique dermatologique (2001), Flammarion ed, Paris 433-438
4. Chulay J.D., Spencer H.C., and Mugambi M. Electrocardiographic changes during treatment of leishmaniasis with pentavalent antimony. Am J Trop Med Hyg 34 (1985) 702-709
5. Hepburn N.C., Nolan J., Fenn L., Herd R.M., Neilson J.M., Sutherland G.R., et al. Cardiac effects of sodium stibogluconate: myocardial, electrophysiological and biochemical studies. QJM 87 (1994) 465-472
6. Hepburn N.C., Siddique I., Howie A.F., Beckett G.J., and Hayes P.C. Hepatotoxicity of sodium stibogluconate in leishmaniasis. Lancet 342 (1993) 238-239
7. e Edition. Pharmaceutical Press 2005;346.
8. Masmoudi A., Maalej N., Mseddi M., Souissi A., Turki H., Boudaya S., et al. Glucantime par voie parentérale : bénéfice versus toxicité. Med Mal Infect 35 (2005) 42-45