Pharmacophore mapping of a series of pyrrolopyrimidines, indolopyrimidines and their congeners as multidrug-resistance-associated protein (MRP1) modulators

Journal of Molecular Modeling

Volumn 14, Issue 10, 2008, Pages 911-921

  Tawari, Nilesh R ^a   Bag, Seema ^a   Degani, Mariam S ^a  

^a UNIVERSITY OF MUMBAI   (India)

Author keywords

3D QSAR; Multi drug resistance; Multidrug resistance associated protein 1; Pharmacophore mapping

Indexed keywords

DAUNORUBICIN; INDOLOPYRIMIDINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN 1; PYRIMIDINE DERIVATIVE; PYRROLOPYRIMIDINE DERIVATIVE; VERAPAMIL;

ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION COEFFICIENT; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; IC 50; LIPOPHILICITY; MULTIDRUG RESISTANCE; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

COMPUTER SIMULATION; HUMANS; HYDROGEN BONDING; INDOLES; INHIBITORY CONCENTRATION 50; ISOXAZOLES; MODELS, MOLECULAR; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PYRIMIDINES; PYRROLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLONES; QUINOXALINES; SILYMARIN; SULFONAMIDES; THIOPHENES;

EID: 50349094786     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-008-0330-z     Document Type: Article

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