The use of RNAi and transgenics to develop viral disease resistant livestock

Developments in Biologicals

Volumn 132, Issue , 2008, Pages 377-382

  Wise, T G ^a   Schafer, D S ^a   Lowenthal, J W ^a   Doran, T J ^a  

^a CSIRO   (Australia)

Author keywords

Disease resistance; Influenza; RNAi; Transgenic

Indexed keywords

EID: 50249167633     PISSN: 14246074     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000317188     Document Type: Conference Paper

References (5)

1. Clark J, Whitelaw B: A Future for Transgenic Livestock. Nat Rev Genet 2003;4:825-833.
2. Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J: RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA 2003;100:2718-2723.
3. Kim DH, Rossi JJ: Coupling of RNAi-mediated target downregulation with gene replacement. Antisense Nucleic Acid Drug Dev 2003;13:151-155.
4. Wise TG, Schafer DJ, Lambeth LS, Tyack SG, Bruce MP, Moore RJ, Doran TJ: Characterisation and comparison of chicken U6 promoters for the expression of short hairpin RNAs. Anim Biotechnol 2007;18:153-162.
5. Heine HG, Trinidad L, Selleck P, Lowther S: Rapid detection of highly pathogenic avian influenza H5N1 virus by TaqMan reverse transcriptase -polymerase chain reaction. Avian Dis 2007;51(Suppl 1):370-372.