Juvenile myelomonocytic leukemia with less aggressive clinical course and KRAS mutation

Pediatric Blood and Cancer

Volumn 51, Issue 4, 2008, Pages 569-

  Imamura, Masaru ^a   Imai, Chihaya ^a   Takachi, Takayuki ^a   Nemoto, Tae ^a   Tanaka, Atsushi ^a   Uchiyama, Makoto ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTRETINOIN;

BONE MARROW BIOPSY; CASE REPORT; DISEASE COURSE; DRUG WITHDRAWAL; GENE MUTATION; HUMAN; HUMAN TISSUE; INFANT; JUVENILE MYELOMONOCYTIC LEUKEMIA; LETTER; LEUKOCYTE COUNT; LEUKOCYTOSIS; MALE; MONOCYTOSIS; ONCOGENE K RAS; ONCOGENE N RAS; PRIORITY JOURNAL; PROGNOSIS; THROMBOCYTE COUNT; TREATMENT RESPONSE;

ANTINEOPLASTIC AGENTS; CHILD, PRESCHOOL; FOLLOW-UP STUDIES; HUMANS; LEUKEMIA, MYELOMONOCYTIC, JUVENILE; MALE; MUTATION; RAS PROTEINS;

EID: 50249113090     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.21626     Document Type: Letter

References (5)

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2. Manabe A, Okamura J, Yumura-Yagi K, et al. Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group. Leukemia 2002;16:645-649.
3. Niemeyer CM, Arico M, Basso G, et al. Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS). Blood 1997;89:3534-3543.
4. Matsuda K, Shimada A, Yoshida N, et al. Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. Blood 2007;109:5477-5480.
5. Flotho C, Kratz CP, Bergsträsser E, et al. Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. Blood 2008;111:966-967.