Thyroidectomies from patients with history of therapeutic radiation during childhood and adolescence have a unique mutational profile

Modern Pathology

Volumn 21, Issue 9, 2008, Pages 1176-1182

  Assaad, Adel ^a   Voeghtly, Laura ^b   Hunt, Jennifer L ^c  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

BRAF mutation; Radiation; Thyroid carcinoma; Tumor suppressor gene

Indexed keywords

ADOLESCENCE; ARTICLE; CHILDHOOD; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA DAMAGE; GENE LOCUS; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INDUCED MUTATION; LARYNX CARCINOMA; NODULAR HYPERPLASIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION EXPOSURE; RISK FACTOR; THYROID CARCINOMA; THYROIDECTOMY;

ADENOCARCINOMA, PAPILLARY; ADENOMA; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; ELECTROPHORESIS, CAPILLARY; FEMALE; HUMANS; LARYNGEAL NEOPLASMS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MUTATION; NEOPLASMS, RADIATION-INDUCED; NUCLEIC ACID HYBRIDIZATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS B-RAF; THYROID NEOPLASMS; THYROIDECTOMY;

EID: 50249085963     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.122     Document Type: Article

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