Risk factors for developing severe clinical course in HUS patients: A national survey in Japan

Pediatrics International

Volumn 50, Issue 4, 2008, Pages 441-446

  Kamioka, Ichiro ^a   Yoshiya, Kunihiko ^b   Satomura, Kenichi ^c   Kaito, Hiroshi ^a   Fujita, Teruo ^a   Iijima, Kazumoto ^d   Nakanishi, Koichi ^e   Yoshikawa, Norishige ^e   Nozu, Kandai ^a   Matsuo, Masafumi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Hara Genitourinary Hospital   (Japan)

^c RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^d NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^e WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Central nervous system disorder; Dialysis; Hemolytic uremic syndrome; National survey; Risk factor

Indexed keywords

ALANINE AMINOTRANSFERASE; C REACTIVE PROTEIN; SODIUM;

ACUTE KIDNEY FAILURE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CAUSE OF DEATH; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CLINICAL FEATURE; DEATH; DIALYSIS; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GASTROINTESTINAL SYMPTOM; HEALTH SURVEY; HEART FAILURE; HEMOLYTIC ANEMIA; HEMOLYTIC UREMIC SYNDROME; HUMAN; JAPAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RISK FACTOR; SODIUM BLOOD LEVEL; THROMBOCYTOPENIA;

ADOLESCENT; ALANINE TRANSAMINASE; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; DATA COLLECTION; FEMALE; HEMOLYTIC-UREMIC SYNDROME; HUMANS; INFANT; JAPAN; MALE; RENAL DIALYSIS; RISK FACTORS; SODIUM;

EID: 50249083363     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2008.02605.x     Document Type: Article

References (34)

1. Remuzzi G, Ruggenenti P. The hemolytic uremic syndrome. Kidney Int. 1995 47 : 2 19.
2. Bitzan M, Bickford BB, Foster GH. Verotoxin (shiga toxin) sensitizes renal epithelial cells to increased heme toxicity: Possible implications for the hemolytic uremic syndrome. J. Am. Soc. Nephrol. 2004 15 : 2334 43.
3. Steinborn M, Leiz S, Rudisser K, Griebel M, Harder T, Hahn H. CT and MRI in haemolytic uraemic syndrome with central nervous system involvement: Distribution of lesions and prognostic value of imaging findings. Pediatr. Radiol. 2004 34 : 805 10.
4. Kuhlback B, Pasternack A, Launiala K, Stenberg M. Serum creatine and creatinine in children and adolescents. Scand. J. Clin. Lab. Invest. 1968 22 : 37 40.
5. Taguchi T, Uchida H, Kiyokawa N et al. Verotoxins induce apoptosis in human renal tubular epithelium derived cells. Kidney. Int. 1998 53 : 1681 88.
6. Pijpers AH, van Setten PA, van den Heuvel LP et al. Verocytotoxin-induced apoptosis of human microvascular endothelial cells. J. Am. Soc. Nephrol. 2001 12 : 767 78.
7. Filler G, Radhakrishnan S, Strain L, Hill A, Knoll G, Goodship TH. Challenges in the management of infantile factor H associated hemolytic uremic syndrome. Pediatr. Nephrol. 2004 19 : 908 11.
8. Siegler RL, Pavia AT, Hansen FL, Christofferson RD, Cook JB. Atypical hemolytic-uremic syndrome: A comparison with postdiarrheal disease. J. Pediatr. 1996 128 : 505 11.
9. Cimolai N, Morrison B, Carter JE. Risk factors for central nervous system manifestations of gastroenteritis-associated hemolytic-uremic syndrome. Pediatrics 1992 90 : 616 21.
10. Bale JF Jr., Brasher C, Siegler RL. CNS manifestations of the hemolytic-uremic syndrome. Relationship to metabolic alterations and prognosis. Am. J. Dis. Child. 1980 134 : 869 72.
11. Noris M, Remuzzi G. Hemolytic uremic syndrome. J. Am. Soc. Nephrol. 2005 16 : 1035 50.
12. Robson WL, Fick GH, Wilson PC. Prognostic factors in typical postdiarrhea hemolytic-uremic syndrome. Child Nephrol. Urol. 1988-89 9 : 203 7.
13. Siegler RL, Pavia AT, Christofferson RD, Milligan MK. A 20-year population-based study of postdiarrheal hemolytic uremic syndrome in Utah. Pediatrics 1994 94 : 35 40.
14. Cimolai N, Carter JE, Morrison BJ, Anderson JD. Risk factors for the progression of Escherichia coli O157: H7 enteritis to hemolytic-uremic syndrome. J. Pediatr. 1990 116 : 589 92.
15. Rowe PC, Orrbine E, Wells GA, McLaine PN. Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988. The Canadian Pediatric Kidney Disease Reference Centre. J. Pediatr. 1990 119 : 218 24.
16. Dundas S, Todd WT, Stewart AI, Murdoch PS, Chaudhuri AK, Hutchinson SJ. The central Scotland Escherichia coli O157:H7 outbreak: Risk factors for the hemolytic uremic syndrome and death among hospitalized patients. Clin. Infect. Dis. 2001 33 : 923 31.
17. Gianviti A, Tozzi AE, De Petris L et al. Risk factors for poor renal prognosis in children with hemolytic uremic syndrome. Pediatr. Nephrol. 2003 18 : 1229 35.
18. Milford D, Taylor CM. Hyponatraemia and haemolytic uraemic syndrome. Lancet 1989 1 : 439.
19. Murakami T, Matoba H, Kuga Y, Ozawa S, Kubota K, Yoshida S. Hyponatremia in a patient with chronic inflammatory disease. Intern. Med. 1989 37 : 792 5.
20. Hughes AK, Stricklett PK, Kohan DE. Shiga toxin-1 regulation of cytokine production by human glomerular epithelial cells. Nephron 2001 88 : 14 23.
21. Mocan H, Mocan MZ. Postpartum hemolytic uremic syndrome with a more severe liver involvement. Clin. Nephrol. 1998 49 : 319 20.
22. Upadhyaya K, Barwick K, Fishaut M, Kashgarian M, Siegel NJ. The importance of nonrenal involvement in hemolytic-uremic syndrome. Pediatrics 1980 65 : 115 20.
23. Pan CG, Leichter HE, Werlin SL. Hepatocellular injury in Streptococcus pneumoniae-associated hemolytic uremic syndrome in children. Pediatr. Nephrol. 1995 9 : 690 93.
24. Bradham CA, Plumpe J, Manns MP, Brenner DA, Trautwein C. Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am. J. Physiol. 1998 275 : G387 92.
25. Eisenhauer PB, Chaturvedi P, Fine RE et al. Tumor necrosis factor alpha increases human cerebral endothelial cell Gb3 and sensitivity to Shiga toxin. Infect. Immun. 2001 69 : 1889 94.
26. Obrig TG, Louise CB, Lingwood CA, Boyd B, Barley-Maloney L, Daniel TO. Endothelial heterogeneity in Shiga toxin receptors and responses. J. Biol. Chem. 1993 268 : 15 484 8.
27. van de Kar NC, Monnens LA, Karmali MA, van Hinsbergh VW. Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: Implications for the pathogenesis of the hemolytic uremic syndrome. Blood 1992 80 : 2755 64.
28. Kaye SA, Louise CB, Boyd B, Lingwood CA, Obrig TG. Shiga toxin-associated hemolytic uremic syndrome: Interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro. Infect. Immun. 1993 61 : 3886 91.
29. Siegler RL. Spectrum of extrarenal involvement in postdiarrheal hemolytic-uremic syndrome. J. Pediatr. 1994 125 : 511 18.
30. Ganapathi MK, Rzewnicki D, Samols D, Jiang SL, Kushner I. Effect of combinations of cytokines and hormones on synthesis of serum amyloid A and C-reactive protein in Hep 3B cells. J. Immunol. 1991 147 : 1261 5.
31. Eisenhauer PB, Jacewicz MS, Conn KJ et al. Escherichia coli Shiga toxin 1 and TNF-alpha induce cytokine release by human cerebral microvascular endothelial cells. Microb. Pathog. 2004 36 : 189 96.
32. Sheth KJ, Swick HM, Haworth N. Neurological involvement in hemolytic-uremic syndrome. Ann. Neurol. 1986 19 : 90 93.
33. Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N. Engl. J. Med. 2000 342 : 1930 36.
34. Mead PS, Griffin PM. Escherichia coli O157:H7. Lancet 1998 352 : 1207 12.