Effect of the spraying conditions and nozzle design on the shape and size distribution of particles obtained with supercritical fluid drying

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 1, 2008, Pages 389-401

  Bouchard, Andréanne ^a   Jovanović, Nataša ^b   de Boer, Anne H ^c   Martín, Ángel ^d   Jiskoot, Wim ^b,e   Crommelin, Daan J A ^b   Hofland, Gerard W ^a   Witkamp, Geert Jan ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d UNIVERSITY OF VALLADOLID   (Spain)

^e LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Atomisation; Computational fluid dynamics; Lysozyme; Mass transfer; Particle size distribution

Indexed keywords

ALCOHOL; CARBON DIOXIDE; LYSOZYME;

AQUEOUS SOLUTION; ARTICLE; COMPARATIVE STUDY; DRUG FORMULATION; DYNAMICS; FLOW RATE; MORPHOLOGY; PARTICLE SIZE; PRESSURE; SPRAY DRYING; SUPERCRITICAL FLUID;

CARBON DIOXIDE; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; DESICCATION; EQUIPMENT DESIGN; ETHANOL; MODELS, CHEMICAL; MURAMIDASE; PARTICLE SIZE; POWDERS; RHEOLOGY; SOLVENTS; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 50149109586     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.03.020     Document Type: Article

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