Clinical efficacy of modified preoperative neoadjuvant chemotherapy in the treatment of locally advanced (stage IB2 to IIB) ervical ancer: randomized study

Gynecologic Oncology

Volumn 110, Issue 3, 2008, Pages 308-315

  Chen, Huijun ^a   Liang, Chuan ^a   Zhang, Lei ^a   Huang, Shuang ^b   Wu, Xufeng ^a  

^a WUHAN UNIVERSITY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Locally advanced cervical cancer; Neoadjuvant chemotherapy; Survival

Indexed keywords

CISPLATIN; FLUOROURACIL; MITOMYCIN C;

ADJUVANT CHEMOTHERAPY; ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; HEALTH HAZARD; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PELVIS LYMPH NODE; PREOPERATIVE CARE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; STATISTICAL SIGNIFICANCE; UTERINE CERVIX CANCER;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CISPLATIN; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; HYSTERECTOMY; LYMPH NODE EXCISION; MIDDLE AGED; MITOMYCIN; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PREOPERATIVE CARE; SURVIVAL RATE; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 50149106727     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2008.05.026     Document Type: Article

References (35)

1. Thomas G.M. Improved treatment for cervical cancer-concurrent chemotherapy and radiotherapy. N. Engl. J. Med. 340 (1999) 1198-1200
2. Sardi J., Sananes C., Giaroli A., Bayo J., Rueda N.G., Vighi S., Guardado N., Paniceres G., Snaidas L., and Vico C. Results of a prospective randomized trial with neoadjuvant chemotherapy in stage IB, bulky, squamous carcinoma of the cervix. Gynecol. Oncol. 49 2 (1993) 156-165
3. Sevin B.U., Nadji M., Lampe B., Lu Y., Kilsenbeck S., Koechli O.R., and Averette H.E. Prognostic factors of early stage cervical cancer treated by radical hysterectomy. Cancer 76 10supply (1995) 1978-1986
4. Horn L.C., Fischer U., Raptis G., Bilek K., and Hentschel B. Tumor size is of prognostic value in surgically treated FIGO stage II cervical cancer. Gynecol. Oncol. 107 (2007) 310-315
5. Trattner M., Graf A.H., Lax S., Forstner R., Dandachi N., Haas J., Pickel H., Reich O., Staudach A., and Winter R. Prognostic factors in surgically treated stage Ib-IIb cervical carcinomas with special emphasis on the importance of tumor volume. Gynecol. Oncol. 82 (2001) 11-16
6. Maria T., Anton-H G., Sigurd L., Rosemarie F., Nadia D., Josef H., Helmut P., Olaf R., Alfons S., and Raimund W. Prognostic factors in surgically treated stage Ib-IIb cervical carcinomas with special emphasis on the importance of tumor volume. Gynecol. Oncol. 82 (2001) 11-16
7. Sardi J.E., Giaroli A., Sananes C., Ferreira M., Soderini A., Bermudez A., Snaidas L., Vighi S., Gomez Rueda N., and di Paola G. Long-term follow-up of the first randomized trial using neoadjuvant chemotherapy in stage Ib squamous carcinoma of the cervix: the final results. Gynecol. Oncol. 67 1 (1997) 61-69
8. Park D.C., Kim J.H., Lew Y.O., Kim D.H., and Namkoong S.E. Phase II trial of neoadjuvant paclitaxel and cisplatin in uterine cervical cancer. Gynecol. Oncol. 92 (2004) 59-63
9. DeSouza N.M., Soutter W.P., Rustin G., Mahon M.M., Jones B., Dina R., and McIndoe G.A. Use of neoadjuvant chemotherapy prior to radical hysterectomy in cervical cancer: monitoring tumour shrinkage and molecular profile on magnetic resonance and assessment of 3-year outcome. Br. J. Cancer 90 12 (2004) 2326-2331
10. Chel Hun C., Tae-Joong K., Jeong-Won L., Byoung-Gie K., Je-Ho L., and Duk-soo B. II study of neoadjuvant chemotherapy with mitomycin-c vincristine and cisplatin (MVC) in patients with stages IB2-IIB cervical carcinoma. Gynecol. Oncol. 104 (2007) 64-69
11. Benedetti-Panici P., Greggi S., Colombo A., Amoroso M., Smaniotto D., Giannarelli D., Amunni G., Raspagliesi F., Zola P., Mangioni C., and Landoni F. Neoadjuvant chemotherapy and radical surgery versus exclusive radiotherapy in locally advanced cervical cancer: results from the Italian multicenter randomised study. J. Clin. Oncol. 20 (2002) 179-188
12. Yamakawa Y., Fujimura M., Hidaka T.M.D., Hori S., and Saito S. Neoadjuvant intraarterial infusion chemotherapy in patients with stage IB2-IIIB cervical cancer. Gynecol. Oncol. 77 (2000) 264-270
13. Dueñas-Gonzalez A., López-Graniel C., González-Enciso A., Cetina L., Rivera L., Mariscal I., Montalvo G., Gómez E., de la Garza J., Chanona G., and Mohar A. A phase II study of multimodality treatment for locally advanced cervical cancer: neoadjuvant carboplatin and paclitaxel followed by radical hysterectomy and adjuvant cisplatin chemoradiation. Ann. Oncol. 14 8 (2003) 1278-1284
14. Zanetta G., Lissoni A., Pellegrino A., Sessa C., Colombo N., Gueli-Alletti D., and Mangioni C. Neoadjuvant chemotherapy with cisplatin, ifosfamide and paclitaxel for locally advanced squamous-cell cervical cancer. Ann. of. Oncol. 9 (1998) 977-980
15. D'Agostino G., Distefano M., Greggi S., Salerno M., Ferrandina G., Poerio A., Mancuso S., and Scambia G. Neoadjuvant treatment of locally advanced carcinoma of the uterine cervix with epirubicin, paclitaxel and cisplatin. Cancer Chemother. Pharmacol. 49 3 (2002) 256-260
16. Eddy G.L., Bundy B.N., Creasman W.T., Spirtos N.M., Mannel R.S., Hannigan E., and O'Connor D. Treatment of ("bulky") stage IB cervical cancer with or without neoadjuvant vincristine and cisplatin prior to radical hysterectomy and pelvic/para-aortic lymphadenectomy: a phase III trial of the Gynecologic Oncology Group. Gynecol. Oncol. 106 (2007) 362-369
17. Behtash N., Nazari Z., Ayatollahi H., Modarres M., Ghaemmaghami F., and Mousavi A. Neoadjuvant chemotherapy and radical surgery compared to radical surgery alone in bulky stage IB-IIA cervical cancer. Eur. J. Surg. Oncol. 32 10 (2006) 1226-1230
18. Finan M.A., and Kline R.C. Controversies in the management of stage IB cervical cancer. Obstet/Gynecol (1998) 77-100
19. Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials. Eur. J. Cancer 39 (2003) 2470-2486
20. Sardi J.E., Boixadera M.A., and Sardi J.J. Neoadjuvant chemotherapy in cervical cancer: a new trend. Curr. Opin. Obstet. Gynecol. 17 1 (2005) 43-47
21. Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration (NACCCMA). Neoadjuvant chemotherapy for locally advanced cervix cancer. Cochrane Database of Systematic Reviews, 2004, Issue 1. Art. No.: CD001774. doi:10.1002/14651858. CD001774. pub2.
22. WHO. Handbook for reporting results of cancer treatment. (1989), W.H.O. Offset Publication, WHO, Geneva No. 48
23. Eddy G.L., Manetta A., Alvarez R.D., Williams L., and Creasman W.T. Neoadjuvant chemotherapy with vincristine and cisplatin followed by radical hysterectomy and pelvic lymphadenectomy for FIGO stage IB bulky cervical cancer: a Gynecologic Oncology Group pilot study. Gynecol. Oncol. 57 3 (1995) 412-416
24. Bloss J.D., Lucci III J.A., DiSaia P.J., Manetta A., Schiano M.A., Ramsinghani N., and Berman M.L. A phase II trial of neoadjuvant chemotherapy prior to radical hysterectomy and/or radiation therapy in the management of advanced carcinoma of the uterine cervix. Gynecol. Oncol. 59 1 (1995) 105-110
25. Chang T.C., Lai C.H., Hong J.H., Hsueh S., Huang K.G., Chou H.H., Tseng C.J., Tsai C.S., Chang J.T., Lin C.T., Chang H.H., Chao P.J., Ng K.K., Tang S.G., and Soong Y.K. Randomized trial of neoadjuvant cisplatin, vincristine, bleomycin, and radical hysterectomy versus radiation therapy for bulky stage IB and IIA cervical cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. J. Clin. Oncol. 18 8 (2000) 1740-1747
26. Katsumata N., Yoshikawa H., Hirakawa T., et al. Phase III randomized trial of neoadjuvant chemotherapy (NAC) followed by radical hysterectomy (RH) versus RH for bulky stage I/II cervical cancer. ASCO Annu. Meet. Proc. 24 (2006) 5013
27. Benedetti-Panici P., Bellati F., Pastore M., Manci N., Musella A., Pauselli S., Angelucci M., Muzii L., and Angioli R. An update in neoadjuvant chemotherapy in cervical cancer. Gynecol. Oncol. 107 1 Suppl 1 (2007) 20-22
28. Bolis G., van Zainten-Przybysz I., Scarfone G., Zanaboni F., Scarabelli C., Tateo S., Calabrese M., and Parazzini F. Determinants of response to a cisplatin-based regimen as neoadjuvant chemotherapy in stage IB-IIB invasive cervical cancer. Gynecol. Oncol. 63 1 (1996) 62-65
29. Iwasaka T., Fukuda K., Hara K., Yokoyama M., Nakao Y., Chiyama M., and Sugimori H. Neoadjuvant chemotherapy with mitomycin C, etoposide, and cisplatin for adenocarcinoma of the cervix. Gynecol. Oncol. 70 (1998) 236-240
30. Benedetti-Panici P., Scambia G., Baiocchi G., Greggi S., Ragusa G., Gallo A., Conte M., Battaglia F., Laurelli G., Rabitti C., Capelli A., and Mancuso S. Neoadjuvant chemotherapy and radical surgery in locally advanced cervical cancer: prognostic factors for response and survival. Cancer 67 (1991) 372-379
31. Namkoong S.E., Park J.S., Kim J.W., Bae S.N., Han G.T., Lee J.M., Jung J.K., and Kim S.J. Comparative study of patients with locally advanced stages Ib and II cervical cancer treatment by radical surgery with and without preoperative adjuvant chemotherapy. Gynecol. Oncol. 59 (1995) 136-142
32. Giaroli A., Sananes C., Sardi J.E., Maya A.G., Bastardas M.L., Snaidas L., Rueda N.G., Vighi S., and di Paola G.R. Lymph node metastases in carcinoma of the cervix uteri: response to neoadjuvant chemotherapy and its impact on survival. Gynecol. Oncol. 39 1 (1990) 34-39
33. Kim D.S., Moon H., Kim K.T., Hwang Y., Cho S., and Kim S.R. Two-year survival: preoperative adjuvant chemotherapy in the treatment of cervical cancer stages IB and II with bulky tumor. Gynecol. Oncol. 33 (1989) 225-230
34. Panici P.B., Greggi S., Scambia G., Ragusa G., Baiocchi G., Battaglia F., Coronetta F., and Mancuso S. High-dose cisplatin and bleomycin neoadjuvant chemotherapy plus radical surgery in locally advanced cervical carcinoma: a preliminary report. Gynecol. Oncol. 41 3 (1991) 212-216
35. Giardina G., Richiardi G., Danese S., Ottone P., Ohlmeier U., and Gargiulo T. Weekly cisplatin as neoadjuvant chemotherapy in locally advanced cervical cancer: a well tolerate alternative. Eur. J. Gynaecol. Oncol. 18 (1997) 173-176