Compound mutations in long QT syndrome assessed by a computer model

Computers in Cardiology

Volumn 33, Issue , 2006, Pages 201-204

  Grandi, Eleonora ^a   Puglisi, J L ^b   Bers, D M ^b   Severi, S ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; ARSENIC COMPOUNDS; CARDIOLOGY; CHLORINE COMPOUNDS; COMPUTER SYSTEMS; FOOD ADDITIVES; HEALTH; KETONES;

ACTION POTENTIALS; ADDITIVE EFFECTS; CARDIAC ARRHYTHMIAS; CHANNEL MUTATIONS; COMPUTER MODELLING; LONG QT SYNDROME; SUDDEN DEATH; WAVE FORMS;

MATHEMATICAL MODELS;

EID: 50149103935     PISSN: 02766574     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (7)

1. Ching CK, Tan Ec. Congenital long QT syndromes: clinical features, molecular genetics and genetic testing. Expert Review of Molecular Diagnostics 2006;6(3):365-74.
2. Schwartz PJ, Priori SG, Napolitano C. How Really Rare Are Rare Diseases?:. The Intriguing Case of Independent Compound Mutations in the Long QT Syndrome. Journal of Cardiovascular Electrophysiology 2003;14(10):1120-1.
3. Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC. Compound Mutations: A Common Cause of Severe Long-QT Syndrome. Circulation 2004 Apr 20;109(15):1834-41.
4. Yamaguchi M, Shimizu M, Ino H, Terai H, Hayashi K, Kaneda T, et al. Compound heterozygosity for mutations Asp611 - >Tyr in KCNQ1 and Asp609 - >Gly in KCNH2 associated with severe long QT syndrome. Clin Sci (Lond). 108[2], 143-150. 2005.
5. Kambouris NG, Nuss HB, Johns DC, Tomaselli GF, Marban E, Balser JR. Phenotypic Characterization of a Novel Long-QT Syndrome Mutation (R1623Q) in the Cardiac Sodium Channel. Circulation 1998 Feb 24;97(7):640-4.
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7. LabHEART The Official Homepage 2006 Available from: URL: http://www.labheart.org