Functional role of Na+/H+ exchanger in Ca 2+ influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells

Journal of Pharmacological Sciences

Volumn 107, Issue 4, 2008, Pages 456-459

  Horinouchi, Takahiro ^a   Miyake, Yumie ^a   Nishiya, Tadashi ^a   Nishimoto, Arata ^a   Morishima, Shigeru ^b   Muramatsu, Ikunobu ^b   Miwa, Soichi ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

Endothelin type A receptor; Intracellular free Ca2+ concentration; Na+ H+ exchanger

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 5 (N ETHYL N ISOPROPYL)AMILORIDE; CALCIUM ION; ENDOTHELIN A RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CELL PH; CELL VOLUME; CHO CELL; CONTROLLED STUDY; NONHUMAN; PATCH CLAMP; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SODIUM TRANSPORT;

EID: 50149088080     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08135SC     Document Type: Article

References (15)

1. + exchanger. Can J Physiol Pharmacol. 2006;84:1081-1095.
2. + exchanger, NHE1: structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol. 2002;42:527-552.
3. Cingolani H, Ennis I. Sodium-hydrogen exchanger, cardiac overload, and myocardial hypertrophy. Circulation. 2007;115:1090-1100.
4. 1 adrenoceptor in CHO cells. J Physiol. 2001;535:107-113.
5. 3-adrenoceptor revealed by SR59230A [3-(2-ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S- 2-propanol oxalate]. J Pharmacol Exp Ther. 2005;312:1064-1074.
6. A receptors. Mol Pharmacol. 2002;62:75-80.
7. 2+ entry channels involved in endothelin-1-induced contractions of vascular smooth muscle cells. J Smooth Muscle Res. 2005;41:61-75.
8. i in ventricular myocytes. Exp Biol Med. 2006;231:865-870.
9. Russell FD, Molenaar P. The human heart endothelin system: ET-1 synthesis, storage, release and effect. Trends Pharmacol Sci. 2000;21:353-359.
10. A receptor. Eur J Pharmacol. 2007;566:28-33.
11. 1A-adrenoceptor. J Pharmacol Sci. 2007;105:103-111.
12. McConnell HM, Owicki JC, Parce JW, Miller DL, Baxter GT, Wada HG, et al. The cytosensor microphysiometer: biological applications of silicon technology. Science. 1992;257:1906-1912.
13. Spassova MA, Soboloff J, He LP, Hewavitharana T, Xu W, Venkatachalam K, et al. Calcium entry mediated by SOCs and TRP channels: variations and enigma. Biochim Biophys Acta. 2004;1742:9-20.
14. + exchanger NHE1: effects on the sympathetic nervous system in heart failure. Cardiovasc Drug Rev. 2007;25:123-131.
15. + regulation in normal and failing hearts. J Pharmacol Sci. 2006;100:315-322.