Regeneration of dentin-pulp complex with cementum and periodontal ligament formation using dental bud cells in gelatin-chondroitin-hyaluronan tri-copolymer scaffold in swine

Journal of Biomedical Materials Research - Part A

Volumn 86, Issue 4, 2008, Pages 1062-1068

  Kuo, Tzong Fu ^a   Huang, An Ting ^a   Chang, Hao Hueng ^a,b   Lin, Feng Huei ^a   Chen, San Tai ^a   Chen, Rung Shu ^a   Chou, Cheng Hung ^a   Lin, Hsin Chi ^a   Chiang, Han ^a   Chen, Min Huey ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Dental bud cells; Gelatin chondroitin hyaluronan tri copolymer; Scaffold; Tooth regeneration

Indexed keywords

CHLORINE COMPOUNDS; COPOLYMERIZATION; PAINTING; PLASTIC PRODUCTS; POLYMERS; PROTEINS; PULP; SCAFFOLDS; TECHNOLOGY; TISSUE ENGINEERING;

CHONDROITIN; DENTAL BUD CELLS; EXPERIMENTAL ANIMALS; GELATIN-CHONDROITIN-HYALURONAN TRI-COPOLYMER; HYALURONAN; IMMUNOHISTOCHEMICAL STAINING; IN-SITU; IN-VITRO; PERIODONTAL LIGAMENTS; SCAFFOLD; TOOTH REGENERATION; TOOTH STRUCTURE;

LIGAMENTS;

CHONDROITIN; COPOLYMER; EOSIN; GELATIN; HEMATOXYLIN; HYALURONIC ACID;

ALVEOLAR BONE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOGRAFT; CALCIFICATION; CELL CULTURE; CELL EXPANSION; CELL ISOLATION; CEMENTUM; CONTROLLED STUDY; DENTIN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MANDIBLE; MOLAR TOOTH; NONHUMAN; OSSIFICATION; PERIODONTAL LIGAMENT; REGENERATION; STAINING; STRUCTURE ANALYSIS; SWINE; TISSUE ENGINEERING; TOOTH EXTRACTION; TOOTH PULP; TOOTH SOCKET;

ANIMALS; CELLS, CULTURED; CHONDROITIN; DENTAL CEMENTUM; DENTAL PULP; DENTIN; GELATIN; HYALURONIC ACID; IMMUNOHISTOCHEMISTRY; JAW; PERIODONTAL LIGAMENT; REGENERATION; STAINING AND LABELING; SWINE; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TOOTH;

CELLS; CHLORINE COMPOUNDS; COPOLYMERIZATION; GELATIN; PAINTING; POLYMERS; PROTEINS; TOOTH;

EID: 50149087130     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31746     Document Type: Article

References (15)

1. Thesleff I, Vaahtokari A, Partanen AM. Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. Int J Dev Biol 2005;39:35-50.
2. Modino SA, Sharpe PT. Tissue engineering of teeth using adult stem cells. Arch Oral Biol 2005;50:255-258.
3. Nakashima M, Reddi AH. The application of bone morphogenetic proteins to dental tissue engineering. Nat Biotechnol 2003;21:1025-1032.
4. Zhang YD, Chen Z, Song YQ, Liu C, Chen YP. Making a tooth: Growth factors, transcription factors, and stem cells. Cell Res 2005;15:301-316.
5. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 2000;97:13625-13630.
6. Nakashima M, Akamine A. The application of tissue engineering to regeneration of pulp and dentin in endodontics. J Endod 2005;31:711-718.
7. Honda MJ, Ohara T, Sumita Y, Ogaeri T, Kagami H, Ueda M. Preliminary study of tissue-engineered odontogenesis in the canine jaw. J Oral Maxillofac Surg 2006;64:283-289.
8. Choi RS, Vacanti JP. Preliminary studies of tissue-engineered intestine using isolated epithelial organoid units on tubular synthetic biodegradable scaffolds. Transplant Proc 1997;29:848-851.
9. Young CS, Terada S, Vacanti JP, Vacanti JP, Honda M, Bartlett JD, Yelick PC. Tissue engineering of complex tooth structures on biodegradable polymer scaffolds. J Dent Res 2002;81:695-700.
10. Duailibi MT, Duailibi SE, Young CS, Bartlett JD, Vacanti JP, Yelick PC. Bioengineered teeth from cultured rat tooth bud cells. J Dent Res 2004;83:523-528.
11. Bostman OM, Pihlajamaki HK. Adverse tissue reactions to bioabsorbable fixation devices. Clin Orthop Relat Res 2000;371:216-227.
12. Chang CH, Liu HC, Lin CC, Chou CH, Lin FH. Gelatin-chondroitin-hyaluronan tri-copolymer scaffold for cartilage tissue engineering. Biomaterials 2003;24,4853-4858.
13. Honda MJ, Sumita Y, Kagami H, Ueda M. Histological and immunohistochemical studies of tissue engineered odontogenesis. Arch Histol Cytol 2005;68:89-101.
14. Gronthos S, Brahim J, Li W, Fisher LW, Cherman N, Boyde A, DenBesten P, Robey PG, Shi S. Stem cell properties of human dental pulp stem cells. J Dent Res 2002;81:531-535.
15. Rutherford RB, Spangberg L, Tucker M, Rueger D, Charette M. The time-course of the induction of reparative dentine formation in monkeys by recombinant human osteogenic protein-1. Arch Oral Biol 1994;39:833-838.