A novel scaffold based on formation and agglomeration of PCL microbeads by freeze-drying

Journal of Biomedical Materials Research - Part A

Volumn 86, Issue 4, 2008, Pages 1012-1022

  Gercek I ^a   Tigli R S ^a   Gumusderelioglu, M ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Biodegradation; Cell proliferation; Freeze drying; Polycaprolactone; Tissue scaffold

Indexed keywords

AGGLOMERATION; BIOMECHANICS; CELL CULTURE; CURING; DEWATERING; DRYING; IMAGING TECHNIQUES; LIGAMENTS; LOW TEMPERATURE DRYING; MECHANICAL PROPERTIES; MECHANICAL STABILITY; MICROSPHERES; PHOTOGRAPHY; POLYMER SOLUTIONS; POLYMERS; POROSITY; TECHNOLOGY; THREE DIMENSIONAL; TISSUE ENGINEERING;

BIODEGRADATION; CELL PROLIFERATION; DEGRADABILITY; FREEZE-DRYING; MICRO-BEADS; NARROW SIZE DISTRIBUTIONS; PCL SCAFFOLDS; PERIODONTAL LIGAMENT CELLS; POLYCAPROLACTONE; POLYCAPROLACTONE SCAFFOLDS; POLYMER COMPOSITIONS; SCAFFOLD PROPERTIES; TETRA-HYDROFURAN; THREE-DIMENSIONAL STRUCTURING; TISSUE SCAFFOLD; TISSUE-ENGINEERING SCAFFOLDS;

SCAFFOLDS;

MICROSPHERE; MOLECULAR SCAFFOLD; POLYCAPROLACTONE; TETRAHYDROFURAN;

ARTICLE; BIODEGRADABILITY; CELL ACTIVITY; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; FREEZE DRYING; MICROANALYSIS; MICROMORPHOLOGY; MOLECULAR MECHANICS; NANOPORE; PARTICLE SIZE; PERIODONTAL LIGAMENT; POROSITY; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING;

BIOMECHANICS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOSKELETON; FREEZE DRYING; HUMANS; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; MICROSPHERES; PERIODONTAL LIGAMENT; POLYESTERS; POROSITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE SCAFFOLDS; WEIGHT LOSS; WETTABILITY;

EID: 50149086314     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31723     Document Type: Article

References (39)

1. Hou Q, Grijpma DW, Feijen J Preparation of interconnected highly porous polymeric structures by a replication and freeze-drying process. J Biomed Mater Res B Appl Biomater 2003;6:7732-7740.
2. Kim BS, Mooney DJ. Development of biocompatible synthetic extracellular matrices for tissue engineering. Trends Biotechnol 1998;16:224-230.
3. Ng KW, Khor HL, Hutmacher DW. In vitro characterization of natural and synthetic dermal matrices cultured with human dermal fibroblasts. Biomaterials 2004;25:2807-2818.
4. Griffon DJ, Sedighi MR, Schaeffer DV, Eurell JA, Johnson AL. Chitosan scaffolds: Interconnective pore size and cartilage engineering. Acta Biomaterialia 2006;2:313-320.
5. Segura T, Anderson BC, Chung PH, Webber RE, Shull KR, Shea LD. Crosslinked hyaluronic acid hydrogels: A strategy to functionalize and pattern. Biomaterials 2005;26:359-371.
6. Zhao J, Yuan X, Cui Y, Ge Q, Yao K. Preparation and characterization of poly(L-lactide)/poly(e-caprolactone) fibrous scaffolds for cartilage tissue engineering. J Appl Polym Sci 2004;91:1676-1684.
7. Lin CC, Co CC, Ho CC. Micropatterning proteins and cells on polylactic acid and poly(lactide-co-glycolide). Biomaterials 2005;26:3655-3662.
8. Zein I, Hutmacher DW, Tan KC, Teoh SH. Fused deposition modeling of novel scaffold architectures for tissue engineering applications. Biomaterials 2002;23:1169-1185.
9. Zmora S, Glicklis R, Cohen S. Tailoring the pore architecture in 3D alginate scaffolds by controlling the freezing regime during fabrication. Biomaterials 2002;23:4087-4094.
10. Mikos AG, Temenoff JS. Formation of highly porous biodegradable scaffolds for tissue engineering. Electron J Biotechnol 2000;3:1-6.
11. Lo H, Ponticiello MS, Leong KW. Fabrication of controlled release biodegradable foams by phase separation. Tissue Eng 1995;1:15-28.
12. Chen Y, Mak AFT, Wang M, Li J, Wong MS. PLLA scaffolds with biomimetic apatite coating and biomimetic apatite/collagen composite coating to enhance osteoblast-like cells attachment and activity. Surf Coat Technol 2006;201:575-580.
13. Jayasuriya AC, Assad M, Jayatissa AH, Ebraheim NA. Dissolution behavior of biomimetic minerals on 3D PLGA scaffold. Surf Coat Technol 2006;200:6336-6339.
14. Tiǧli RS, Karakeçili A, Gümüş derelioǧlu M. In vitro characterization of chitosan scaffolds: Influence of composition and deacetylation degree. J Mater Sci: Mater Med 2007;18:1665-1674.
15. Mooney DJ, Baldwin DF, Suh NP, Vacanti JP, Langer R. Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents. Biomaterials 1996;17:1417-1422.
16. Aijun W, Qiang A, Wenling C, Chang Z, Yandao G, Nanming Z, Xiufang Z. Fiber-based chitosan tubular scaffolds for soft tissue engineering: Fabrication and in vitro evaluation. Tsinghua Sci Technol 2005;10:449-453.
17. Wang X, Um IC, Fang D, Okamoto A, Hsiao BS, Chu B. Formation of water-resistant hyaluronic acid nanofibers by blowing-assisted electro-spinning and non-toxic post treatments. Polymer 2005;46:4853-4867.
18. Tsang VL, Bhatia SN. Three-dimensional tissue fabrication. Adv Drug Delivery Rev 2004;56:1635-1647.
19. Malafaya PB, Pedro AJ, Peterbauer A, Gabrie IC, Redl H, Reis RL. Chitosan particles agglomerated scaffolds for cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells. J Mater Sci: Mater Med 2005;16:1077-1085.
20. Khor HL, Ng KW, Schantz JT, Phan TT, Lim TC, Teoh SH, Hutmacher DW. Poly(ε-caprolactone) films as a potential substrate for tissue engineering an epidermal equivalent. Mater Sci Eng C 2002;20:71-75.
21. Pernin DE, English JP. Synthetic absorbable polymers: polycaprolactone. In: Dome AJ, Kost J, Wiseman DM, editors. Handbook of Biodegradable Polymers. Amsterdam: Harwood Academic Press; 1997. p 63.
22. Tay BY, Zhang SX, Myint MH, Ng FL, Chandrasekaran M, Tan LKA. Processing of polycaprolactone porous structure for scaffold development. J Mater Process Technol 2007;182:117-121.
23. Williams JM, Adewunmi A, Schek RM, Flanagan CL, Krebsbach PH, Feinberg SE, Hollister SJ, Das S. Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. Biomaterials 2005;26:4817-4827.
24. Saez A, Guzman M, Molpeceres J, Aberturas MR. Freeze-drying of polycaprolactone and poly(D,L-lactic-glycolic) nanoparticles induce minor particle size changes affecting the oral-pharmacokinetics of loaded drugs. Eur J Pharm Biopharm 2000;50:379-387.
25. Sinha VR, Bansal K, Kaushik R, Kumria R, Trehan A. Poly-e-caprolactone microspheres and nanospheres: An overview. Int J Pharm 2004;278:1-23.
26. Reignier J, Huneault MA. Preparation of interconnected poly(ε-caprolactone) porous scaffolds by a combination of polymer and salt particulate leaching. Polymer 2006;47:4703-4717.
27. Yoshimoto H, Shin YM, Terai H, Vacanti JP. Technical note: A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003;24:2077-2082.
28. Thomson RC, Shung AK, Yaszemski MJ, Mikos AG. Polymer scaffold processing. In: Lanza R, Langer R, Vacanti JP, editors. Principles of Tissue Engineering. New York: Acedemic Press; 2000. p 251-261.
29. Prasitsilp M, Jenwithisuk R, Kongsuwan K, Damrongchai N, Watts PJ. Cellular responses to chitosan in vitro: The importance of deacetylation. Mater Sci Mater Med 2000;12:773-778.
30. Chen GP, Ushida Y, Tateishi T. Scaffold design for tissue engineering. Macromol Biosci 2002;2:67-77.
31. Tiaw KS, Goh SW, Hong M, Wang Z, Lan B, Teoh SH. Laser surface modification of poly(e-caprolactone) (PCL) membrane for tissue engineering applications. Biomaterials 2005;26:763-769.
32. Osawa S, Yabe M, Miyamura M, Mizuno K. Preparation of super-hydrophobic surface on biodegradable polymer by transcribing microscopic pattern of water-repellent leaf. Polymer 2006;47:3711-3714.
33. Chen F, Lee CN, Teoh SH. Nanofibrous modification of ultrathin poly(e-caprolactone) membrane via electrospinning. Mater Sci Eng C 2006;27:325-332.
34. Erbil HY, Demirel AL, Avci Y, Mert O. Transformation of a simple plastic into a superhyrophobic surface. Science 2003;299:1377-1380.
35. Huang Y, Onyeri S, Siewe M, Moshfeghian A, Madihally SV. In vitro characterization of chitosan-gelatin scaffolds for tissue engineering. Biomaterials 2005;26:7616-7627.
36. Pena J, Corrales T, Izquierdo-Barba I, Doadrio AL, Vallet-Regi M. Long term degradation of poly(e-caprolactone) films in biologically related fluids. Polym Degrad Stab 2006;91:1424-1432.
37. Chen DR, Bei JZ, Wang SG. Polycaprolactone microparticles and their biodegradation. Polym Degrad Stab 2000;67:455-459.
38. Pastorino L, Pioli F, Zilli M, Converti A, Nicolini C. Lipase-catalyzed degradation of poly(ε-caprolactone). Enzyme Microb Technol 2004;35:321-326.
39. Gümüşderelioǧlu M, Türkoǧlu H. Biomodification of non-woven polyester fabrics by insulin and RGD for use in serum-free cultivation of tissue cells. Biomaterials 2002;23:3927-3935.