C4d staining is a valuable marker in identifying chronic GVHD in colonic biopsies following BMT

Bone Marrow Transplantation

Volumn 42, Issue 3, 2008, Pages 209-211

  Zhang, P L ^a   Wilkerson, M L ^b   Schworer, C M ^c  

^a WILLIAM BEAUMONT HOSPITAL   (United States)

^b GEISINGER MEDICAL CENTER   (United States)

^c WEIS CENTER FOR RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C4D;

ADULT; AGED; ALLOGENIC BONE MARROW TRANSPLANTATION; APLASTIC ANEMIA; AUTOPSY; B CELL LEUKEMIA; CASE REPORT; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL FEATURE; COLON BIOPSY; COLON DISEASE; DEATH; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN TISSUE; LARGE CELL LYMPHOMA; LETTER; LYMPHOCYTOMA; MALE; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL;

AGED; BIOLOGICAL MARKERS; BIOPSY; BONE MARROW TRANSPLANTATION; CAPILLARIES; COLON; COMPLEMENT C4B; FEMALE; GRAFT VS HOST DISEASE; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS;

EID: 50049134897     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2008.132     Document Type: Letter

References (5)

1. Berger SP, Roos A, Daha MR. Complement and the kidney: What the nephrologist needs to know in 2006. Nephrol Dial Transplant 2005; 20: 2613-2619.
2. Feucht HE. Complement C4d in graft capillaries - the missing link in the recognition of humoral alloreactivity. Am J Transplant 2003; 3 646-652.
3. Crespo-Leiro MG, Veiga-Barreiro A, Domenech N, Paniagua MJ, Pinon P, Gonzalez-Cuesta M et al. Humoral heart rejection (severe allograft dysfunction with no signs of cellular rejection or ischemia): Incidence, management and the value of C4d for diagnosis. Am J Transplant 2005; 5: 2560-2564.
4. Asplund S, Gramlich TL. Chronic mucosal changes of the colon in graft-versus-host disease. Mod Pathol 1998; 11: 513-515.
5. Thompson B, Salzman D, Steinhauer J, Lazenby AJ, Wilcox CM. Prospective endoscopic evaluation for gastrointestinal graft-versus-host disease: determination or the best diagnostic approach. Bone Marrow Transplant 2006; 38: 371-376.