Autologous intra-arterial infusion of bone marrow mononuclear cells in patients with critical leg ischemia

International Angiology

Volumn 27, Issue 4, 2008, Pages 281-290

  Chochola, Miroslav ^a   Pytlik R ^a   Kobylka, P ^b   Skalicka L ^a   Kideryova L ^a   Beran, S ^a   Varejka P ^a   Jirat S ^a   Koivanek J ^a   Aschermann, M ^a   Linhart, A ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

Bone marrow; Extremities; Ischemia; Neovascularization; Physiologic; Quality of life

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLLATERAL CIRCULATION; CONTROLLED STUDY; DIGITAL SUBTRACTION ANGIOGRAPHY; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; ILIAC CREST; LEG AMPUTATION; LEG ISCHEMIA; LEG REVASCULARIZATION; MALE; MONONUCLEAR CELL; PILOT STUDY; QUALITY OF LIFE; SAFETY; SHORT FORM 36; STEM CELL; TRANSCUTANEOUS OXYGEN MONITORING; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; AMPUTATION; ANGIOGRAPHY, DIGITAL SUBTRACTION; ANKLE; ARM; BLOOD GAS MONITORING, TRANSCUTANEOUS; BLOOD PRESSURE; BONE MARROW TRANSPLANTATION; COLLATERAL CIRCULATION; CRITICAL ILLNESS; FEASIBILITY STUDIES; FEMALE; HUMANS; INFUSIONS, INTRA-ARTERIAL; ISCHEMIA; LEG; MALE; MIDDLE AGED; PILOT PROJECTS; QUALITY OF LIFE; QUESTIONNAIRES; REGIONAL BLOOD FLOW; REOPERATION; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; WOUND HEALING;

EID: 50049100983     PISSN: 03929590     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Bodily KC, Burgess EM. Contralateral limb and patient survival after leg amputation. Am J Surg 1983;146:280-2
2. Kucan JO, Robson MC. Diabetic foot infections: fate of the contralateral foot. Plast Reconstr Surg 1986;77:439-41.
3. Wolfe JH, Wyatt MG. Critical and subcritical ischaemia. Eur J Vasc Endovasc Surg 1997;13:578-82.
4. Management of peripheral arterial disease (PAD): TransAtlantic Inter-Society Consensus (TASC). Section D: Chronic critical limb ischaemia. Eur J Vasc Endovasc Surg 2000;19 Suppl A:S144-S243.
5. Catalano M. Epidemiology of critical limb ischaemia: North Italian data. Eur J Med 1998;2:11-4.
6. Kalka C, Masuda H, Takahashi T, Kalka-Moll WM, Silver M, Kearney M et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A 2000;97:3422-7.
7. Li S, Zhou B, Han ZC. Therapeutic neovascularization by transplantation of mobilized peripheral blood mononuclear cells for limb ischemia. A comparison between CD34+ and CD34- mononuclear cells. Thromb Haemost 2006;95:301-11.
8. Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H et al., for Therapeutic Angiogenesis using Cell Transplantation (TACT) Study Investigators. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002;360:427-35.
9. Iba O, Matsubara H, Nozawa Y, Fujiyama S, Amano K, Mori Y et al. Angiogenesis by implantation of peripheral blood mononuclear cells and platelets into ischemic limbs. Circulation 2002;106:2019-25.
10. Akar R, Durdu S, Arat M, Tuncay E, Arslan O, Corapcioglu T et al. Therapeutic angiogenesis by autologous transplantation of bone-marrow mononuclear cells for Buerger's patients with retractable limb ischemia: a preliminary report. Turk J Haematol 2004;21:13-21.
11. Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, Ahn S et al. Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg 1997;26:517-38.
12. Ubbink DT, Jacobs MJHM, Slaaf DW. Can transcutaneous oximetry detect nutritive perfusion disturbances in patients with lower limb ischemia? Microvasc Res 1995;49:315-24
13. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30:473-83.
14. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyymi AA et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003; 348:593-600.
15. Barnett D, Janossy G, Lubenko A, Matutes E, Newland A, Reilly JT. Guideline for the flow cytometric enumeration of CD34+ haematopoietic stem cells. Prepared by the CD34+ haematopoietic stem cell working party. General Haematology Task Force of the British Committee for Standards in Haematology. Clin Lab Haematol 1999;21: 301-8.
16. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci U S A 2001;98:10344-9.
17. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001;107:1395-402.
18. Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004;364:141-8.
19. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T et al. Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 2006;355:1199-209.
20. Schächinger V, Erbs S, Elsässer A, Haberbosh W, Hambrecht R, Holschermann H et al., for the REPAIR-AMI Investigators. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006;355:1210-21.
21. Assmus B, Honold J, Schächinger V, Britten MB, Fischer-Rasokat U, Lehman R et al. Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med 2006;355:1222-32.
22. Janssens S, Dubois C, Bogaert J, Theunissen, K, Deroose C, Desmet W et al. Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 2006;367:113-21.
23. Meyer GP, Wollert KC, Lotz J, Steffens J, Lippolt P, Fichtner S et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (Bone marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 2006;113:1287-94.
24. Higashi Y, Kimura M, Hara K, Noma K, Jitsuiki D, Nakagawa K et al. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia. Circulation 2004;109:1215-8.
25. 99mTc-tetrofosmin (TF) perfusion scintigraphy. Cell Transplant 2004;13:429-37.
26. Yamamoto K, Kondo T, Suzuki S, Izawa H, Kobayashi M, Emi N et al. Molecular evaluation of endothelial progenitor cells in patients with ischemic limbs: therapeutic effect by stem cell transplantation. Arterioscler Thromb Vasc Biol 2004;24:e192-6.
27. Ishida A, Ohya Y, Sakuda K, Ohshiro K, Higashiuesato Y, Nakaema M et al. Autologous peripheral blood mononuclear cell implantation for patients with peripheral arterial disease improves limb ischemia. Circ J 2005;69: 1260-5.
28. Nizankovski R, Petriczek T, Skotnicki A, Sczeklik A. The treatment of advanced chronic lower limb ischaemia with marrow stem cell autotransplantation. Kardiol Pol 2005;63:351-60.
29. Miyamoto K, Nishigami K, Nagaya N, Akutsu K, Chiku M, Kamei M et al. Unblinded pilot study of autologous transplantation of bone marrow mononuclear cells in patients with thromboangiitis obliterans. Circulation 2006;114:2679-84.
30. Hernandez P, Cortina L, Artaza H, Pol N, Lam LM, Dorticós E et al. Autologous bone-marrow mononuclear cell implantation in patients with severe lower limb ischaemia: a comparison of using blood cell separator and Ficoll density gradient centrifugation. Atherosclerosis 2006;DOI: 10.1016/j.atherosclerosis.2006.08.025
31. Huang P, Li S, Han M, Xiao Z, Yang R, Han ZC. Autologous transplantation of granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells improves critical limb ischemia in diabetes. Diabetes Care 2005;28:2155-60.
32. Durdu S, Akar AR, Arat M, Sancak T, Eren NT, Ozyurda U. Autologous bone-marrow mononuclear cell implantation for patients with Rutherford grade II-III thromboangiitis obliterans. J Vasc Surg 2006;44:732-9.
33. Kim DI, Kim MJ, Joh JH, Shin SW, Do YS, Moon JY et al. Angiogenesis facilitated by autologous whole bone marrow stem cell transplantation for Buerger's disease. Stem Cells 2006;24:1194-200.
34. Kawamura A, Horie T, Tsuda I, Abe Y, Yamada M, Egawa H et al. Clinical study of therapeutic angiogenesis by autologous peripheral blood stem cell (PBSC) transplantation in 92 patients with critically ischemic limbs. J Artif Organs 2006;9:226-33.
35. Lenk K, Adams V, Lurz P, Erbs S, Linke A, Gielen S et al. Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia. Eur Heart J 2005;26:1903-9.
36. LeBlanck R, Royi J, Demersi C, Vu L, Cantin G. A prospective study of G-CSF effects on hemostasis in allogeneic blood stem cell donors. Bone Marrow Transplant 1999;23:991-6.
37. Kang HJ, Kim HS, Zhang SY, Park KW, Cho HJ, Koo BK et al. Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomized clinical trial. Lancet 2004;363: 751-6.
38. Hill JM, Syed MA, Arai AE, Powell TM, Paul JD, Zalos G et al. Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease. J Am Coll Cardiol 2005;46:1643-8.
39. Kawachi Y, Watanabe A, Uchida T, Yoschizawa K, Kurooka N, Setsu K. Acute arterial thrombosis due to platelet aggregation in a patient receiving granulocyte colony-stimulating factor. Br J Haematol 1996;94:413-6.
40. Pomyje J, Živný J, Šefc L, Plašilová M, Pytlík R, Nečas E. Expression of genes regulating angiogenesis in human circulating hematopoietic cord blood CD34+/CD133±cells. Eur J Haematol 2003;70:143-50.
41. Heil M, Ziegelhoeffer T, Mees B, Schaper W. A different outlook on the role of bone marrow stem cells in vascular growth. bone marrow delivers software not hardware. Circ Res 2004;94:573-4.
42. Dumville JC, Lee AJ, Smith FB, Fowkes FGR. The health-related quality of life of people with peripheral arterial disease in the community: the Edinburgh Artery Study. Br J Gen Pract 2004;54:826-31.
43. Aquarius AE, Denollet J, Hamming JF, Breek JC, De Vries J. Impaired health status and invasive treatment in peripheral arterial disease: a prospective 1-year follow-up study. J Vasc Surg 2005;41:432-42.
44. Kalbaugh CA, Taylor SM, Blackhurst DW, Dellinger MB, Trent EA, Youkey JR. One-year prospective quality-of-life outcomes in patients treated with angioplasty for symptomatic peripheral arterial disease. J Vasc Surg 2006;44: 296-302.