Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury

Critical Care

Volumn 12, Issue 4, 2008, Pages

  Meier, Regula ^a   Béchir, Markus ^a   Ludwig, Silke ^a   Sommerfeld, Jutta ^a   Keel, Marius ^a   Steiger, Peter ^a   Stocker, Reto ^a   Stover, John F ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYPERTENSIVE AGENT; INSULIN; NORADRENALIN;

ADULT; AGED; ARTICLE; BACTEREMIA; BRAIN PERFUSION; CONTINUOUS INFUSION; CONTROLLED STUDY; EDEMA; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INFUSION; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INCIDENCE; INFECTION RATE; INJURY SEVERITY; INTENSIVE CARE UNIT; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PNEUMONIA; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TRAUMATIC BRAIN INJURY; URINARY TRACT INFECTION; ADOLESCENT; BLOOD; BRAIN INJURY; COMPARATIVE STUDY; METABOLISM; MIDDLE AGED; TIME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; BRAIN INJURIES; FEMALE; HUMANS; HYPOGLYCEMIA; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIME FACTORS; YOUNG ADULT;

EID: 50049091025     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc6974     Document Type: Article

References (44)

1. Van Beek JG Mushkudiani NA Steyerberg EW Butcher I McHugh GS Lu J Marmarou A Murray GD Maas AI Prognostic value of admission laboratory parameters in traumatic brain injury: Results from the IMPACT study J Neurotrauma 2007, 24:315-328. 10.1089/neu.2006.0034 17375996
2. Jeremitsky E Omert LA Dunham CM Wilberger J Rodriguez A The impact of hyperglycemia on patients with severe brain injury J Trauma 2005, 58:47-50. 15674149
3. Gale SC Sicoutris C Reilly PM Schwab CW Gracias VH Poor glycemic control is associated with increased mortality in critically ill trauma patients Am Surg 2007, 73:454-460. 17520998
4. Longstreth WT Jr Inui TS High blood glucose level on hospital admission and poor neurological recovery after cardiac arrest Ann Neurol 1984, 15:59-63. 10.1002/ana.410150111 6712194
5. Capes SE Hunt D Malmberg K Gerstein HC Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: A systematic overview Lancet 2000, 355:773-778. 10.1016/S0140-6736(99)08415-9 10711923
6. Vanhorebeek I Langouche L Berghe Van den G Tight blood glucose control: what is the evidence? Crit Care Med 2007, 35:S496-S502. 10.1097/ 01.CCM.0000278051.48643.91 17713399
7. Berghe van den G Wouters P Weekers F Verwaest C Bruyninckx F Schetz M Vlasselaers D Ferdinande P Lauwers P Bouillon R Intensive insulin therapy in the critically ill patients N Engl J Med 2001, 345:1359-1367. 10.1056/NEJMoa011300 11794168
8. Berghe Van den G Schoonheydt K Becx P Bruyninckx F Wouters PJ Insulin therapy protects the central and peripheral nervous system of intensive care patients Neurology 2005, 64:1348-1353. 15851721
9. Bilotta F Caramia R Cernak I Paoloni FP Doronzio A Cuzzone V Santoro A Rosa G Intensive insulin therapy after severe traumatic brain injury: A randomized clinical trial Neurocrit Care 2008. 18373223
10. Vespa PM McArthur D O'Phelan K Glenn T Etchepare M Kelly D Bergsneider M Martin NA Hovda DA Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: A microdialysis study J Cereb Blood Flow Metab 2003, 23:865-877. 10.1097/01.WCB.0000076701.45782.EF 12843790
11. Strong AJ Smith SE Whittington DJ Meldrum BS Parsons AA Krupinski J Hunter AJ Patel S Robertson C Factors influencing the frequency of fluorescence transients as markers of peri-infarct depolarizations in focal cerebral ischemia Stroke 2000, 31:214-222. 10625740
12. Hopwood SE Parkin MC Bezzina EL Boutelle MG Strong AJ Transient changes in cortical glucose and lactate levels associated with peri-infarct depolarisations, studied with rapid-sampling microdialysis J Cereb Blood Flow Metab 2005, 25:391-401. 10.1038/sj.jcbfm.9600050 15716860
13. Strong AJ Hartings JA Dreier JP Cortical spreading depression: An adverse but treatable factor in intensive care? Curr Opin Crit Care 2007, 13:126-133. 10.1097/MCC.0b013e32807faffb 17327732
14. McMullin J Brozek J McDonald E Clarke F Jaeschke R Heels-Ansdell D Leppert R Foss A Cook D Lowering of glucose in critical care: A randomized pilot trial J Crit Care 2007, 22:112-118. 10.1016/ j.jcrc.2006.08.002 17548021
15. Berghe Van den G Wilmer A Hermans G Meersseman W Wouters PJ Milants I Van Wijngaerden E Bobbaers H Bouillon R Intensive insulin therapy in the medical ICU N Engl J Med 2006, 354:449-461. 10.1056/NEJMoa052521 16452557
16. Thomale UW Griebenow M Mautes A Beyer TF Dohse NK Stroop R Sakowitz OW Unterberg AW Stover JF Heterogeneous regional and temporal energetic impairment following controlled cortical impact injury in rats Neurol Res 2007, 29:594-603. 17535559
17. Nelson DW Bellander BM Maccallum RM Axelsson J Alm M Wallin M Weitzberg E Rudehill A Cerebral microdialysis of patients with severe traumatic brain injury exhibits highly individualistic patterns as visualized by cluster analysis with self-organizing maps Crit Care Med 2004, 32:2428-2436. 10.1097/01.CCM.0000147688.08813.9C 15599147
18. Kato T Nakayama N Yasokawa Y Okumura A Shinoda J Iwama T Statistical image analysis of cerebral glucose metabolism in patients with cognitive impairment following diffuse traumatic brain injury J Neurotrauma 2007, 24:919-926. 10.1089/neu.2006.0203 17600509
19. Glenn TC Kelly DF Boscardin WJ McArthur DL Vespa P Oertel M Hovda DA Bergsneider M Hillered L Martin NA Energy dysfunction as a predictor of outcome after moderate or severe head injury: Indices of oxygen, glucose, and lactate metabolism J Cereb Blood Flow Metab 2003, 23:1239-1250. 10.1097/01.WCB.0000089833.23606.7F 14526234
20. Hattori N Huang SC Wu HM Liao W Glenn TC Vespa PM Phelps ME Hovda DA Bergsneider M Acute changes in regional cerebral 18F-FDG kinetics in patients with traumatic brain injury J Nucl Med 2004, 45:775-783. 15136626
21. Wu HM Huang SC Hattori N Glenn TC Vespa PM Yu CL Hovda DA Phelps ME Bergsneider M Selective metabolic reduction in gray matter acutely following human traumatic brain injury J Neurotrauma 2004, 21:149-161. 10.1089/089771504322778613 15000756
22. Bartnik BL Hovda DA Lee PW Glucose metabolism after traumatic brain injury: Estimation of pyruvate carboxylase and pyruvate dehydrogenase flux by mass isotopomer analysis J Neurotrauma 2007, 24:181-194. 10.1089/ neu.2006.0038 17263682
23. Oddo M Schmidt JM Mayer SA Chioléro RL Glucose control after severe brain injury Curr Opin Clin Nutr Metab Care 2008, 11:134-139. 18301088
24. Kelly DF Kozlowski DA Haddad E Echiverri A Hovda DA Lee SM Ethanol reduces metabolic uncoupling following experimental head injury J Neurotrauma 2000, 17:261-272. 10776911
25. Vespa P Boonyaputthikul R McArthur DL Miller C Etchepare M Bergsneider M Glenn T Martin N Hovda D Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury Crit Care Med 2006, 34:850-856. 10.1097/01.CCM.0000201875.12245.6F 16505665
26. de Courten-Myers GM Xi G Hwang JH Dunn RS Mills AS Holland SK Wagner KR Myers RE Hypoglycemic brain injury: Potentiation from respiratory depression and injury aggravation from hyperglycemic treatment overshoots J Cereb Blood Flow Metab 2000, 20:82-92. 10.1097/ 00004647-200001000-00012 10616796
27. Erol A Insulin resistance is an evolutionarily conserved physiological mechanism at the cellular level for protection against increased oxidative stress Bioessays 2007, 29:811-818. 10.1002/bies.20618 17621670
28. Garg R Chaudhuri A Munschauer F Dandona P Hyperglycemia, insulin, and acute ischemic stroke: A mechanistic justification for a trial of insulin infusion therapy Stroke 2006, 37:267-273. 10.1161/ 01.STR.0000195175.29487.30 16306459
29. Kinoshita K Kraydieh S Alonso O Hayashi N Dietrich WD Effect of posttraumatic hyperglycemia on contusion volume and neutrophil accumulation after moderate fluid-percussion brain injury in rats J Neurotrauma 2002, 19:681-692. 10.1089/08977150260139075 12165130
30. Hui L Pei DS Zhang QG Guan QH Zhang GY The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation Brain Res 2005, 1052:1-9. 10.1016/j.brainres.2005.05.043 16018989
31. Krinsley JS Effect of an intensive glucose management protocol on the mortality of critically ill adult patients Mayo Clin Proc 2004, 79:992-1000. 15301325
32. Quinn JA Snyder SL Berghoff JL Colombo CS Jacobi J A practical approach to hyperglycemia management in the intensive care unit: Evaluation of an intensive insulin infusion protocol Pharmacotherapy 2006, 26:1410-1420. 10.1592/phco.26.10.1410 16999651
33. Grey NJ Perdrizet GA Reduction of nosocomial infections in the surgical intensive-care unit by strict glycemic control Endocr Pract 2004, 10(suppl 2):46-52. 15251640
34. De Ciuceis C Rizzoni D Porteri E Boari GE Zani F Miclini M Tiberio GA Giulini SM Paiardi S Rizzardi N Platto C Agabiti-Rosei E Effects of insulin on endothelial and contractile function of subcutaneous small resistance arteries of hypertensive and diabetic patients J Vasc Res 2008, 45:512-520. 10.1159/000128604 18451634
35. Thomson GA Fisher BM Gemmell CG MacCuish AC Gallacher SJ Attenuated neutrophil respiratory burst following acute hypoglycaemia in diabetic patients and normal subjects Acta Diabetol 1997, 34:253-256. 10.1007/ s005920050084 9451468
36. Oldenborg PA Sehlin J The glucose concentration modulates N-formyl-methionyl-leucyl-phenylalanine (fMet-Leu-Phe)-stimulated chemokinesis in normal human neutrophils Biosci Rep 1999, 19:511-523. 10.1023/A:1020286010551 10841268
37. Kanji S Singh A Tierney M Meggison H McIntyre L Hebert PC Standardization of intravenous insulin therapy improves the efficiency and safety of blood glucose control in critically ill adults Intensive Care Med 2004, 30:804-810. 10.1007/s00134-004-2252-2 15127193
38. Vriesendorp TM van Santen S DeVries JH de Jonge E Rosendaal FR Schultz MJ Hoekstra JB Predisposing factors for hypoglycemia in the intensive care unit Crit Care Med 2006, 34:96-101. 10.1097/ 01.CCM.0000194536.89694.06 16374162
39. Clayton SB Mazur JE Condren S Hermayer KL Strange C Evaluation of an intensive insulin protocol for septic patients in a medical intensive care unit Crit Care Med 2006, 34:2974-2978. 17075371
40. Cochran A Davis L Morris SE Saffle JR Safety and efficacy of an intensive insulin protocol in a burn-trauma intensive care unit J Burn Care Res 2008, 29:187-191. 18182920
41. Gandhi GY Nuttall GA Abel MD Mullany CJ Schaff HV O'Brien PC Johnson MG Williams AR Cutshall SM Mundy LM Rizza RA McMahon MM Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: A randomized trial Ann Intern Med 2007, 146:233-243. 17310047
42. Malliopoulou V Xinaris C Mourouzis I Cokkinos AD Katsilambros N Pantos C Kardami E Cokkinos DV High glucose protects embryonic cardiac cells against simulated ischemia Mol Cell Biochem 2006, 284:87-93. 10.1007/ s11010-005-9018-1 16541202
43. Kelleher JA Chan PH Chan TY Gregory GA Modification of hypoxia-induced injury in cultured rat astrocytes by high levels of glucose Stroke 1993, 24:855-863. 8506557
44. Shi H Liu KJ Effects of glucose concentration on redox status in rat primary cortical neurons under hypoxia Neurosci Lett 2006, 410:57-61. 1865501 17055160 10.1016/j.neulet.2006.09.066