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Volumn 869, Issue 1-2, 2008, Pages 45-53
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Isolation and characterization of degradation impurities in epirubicin hydrochloride injection
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Author keywords
Characterization; Chromatography; Degradation impurity; Epirubicin; HPLC; Identification; Lyophilization; Preparative LC; Spectroscopy
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Indexed keywords
CARBOXYLIC ACIDS;
DEGRADATION;
MASS SPECTROMETRY;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
DEGRADATION IMPURITY;
EPIRUBICIN HYDROCHLORIDE;
PREPARATIVE LC;
IMPURITIES;
4 (4 AMINO 5 HYDROXY 6 METHYLTETRAHYDOPYRAN 2 YLOXY) 2,5,12 TRIHYDROXY 7 METHOXY 6,11 DIOXO 1,2,3,4,6,11 HEXAHYDRONAPHTHACENE 2 CARBOXYLIC ACID HYDROXYMETHYL ESTER;
4 (4 AMINO 5 HYDROXY 6 METHYLTETRAHYDROPYRAN 2 YLOXY) 2,5,12 TRIHYDROXY 7 METHOXY 6,11 DIOXO 1,2,3,4,6,11 HEXAHYDRONAPHTHACENE 2 CARBOXYLIC ACID;
CARBOXYLIC ACID DERIVATIVE;
DIMER;
EPIRUBICIN;
ESTER DERIVATIVE;
NAPHTHACENE DERIVATIVE;
TETRAHYDROPYRAN DERIVATIVE;
AQUEOUS SOLUTION;
ARTICLE;
DRUG DEGRADATION;
DRUG FORMULATION;
DRUG IMPURITY;
DRUG STABILITY;
DRUG STRUCTURE;
ELECTROSPRAY MASS SPECTROMETRY;
ISOLATION PROCEDURE;
MASS SPECTROMETRY;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
ANTIBIOTICS, ANTINEOPLASTIC;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG CONTAMINATION;
EPIRUBICIN;
INJECTIONS;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
TANDEM MASS SPECTROMETRY;
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EID: 49949152349
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2008.05.014 Document Type: Article |
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Times cited : (9)
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References (6)
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