Determination of rimonabant in human plasma and hair by liquid chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 872, Issue 1-2, 2008, Pages 115-120

  Grassin Delyle, Stanislas ^a,b   Abe, Emuri ^a   Devillier, Philippe ^b   Alvarez, Jean Claude ^a  

^a RAYMOND POINCARÉ HOSPITAL   (France)

^b FOCH HOSPITAL   (France)

Author keywords

Cannabinoid antagonist; Human hair; Human plasma; Liquid chromatography; Mass spectrometry; Rimonabant

Indexed keywords

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COLUMN CHROMATOGRAPHY; CONCENTRATION (PROCESS); HEALTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; RISK ASSESSMENT; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; STANDARDS;

ACCURACY AND PRECISION; C18 COLUMN; CALIBRATION CURVES; CANNABINOID ANTAGONIST; DIETHYL ETHERS; ELECTRO SPRAYING; FORENSIC TOXICOLOGY; HUMAN HAIR; HUMAN PLASMA; HUMAN PLASMAS; INTERNAL STANDARD; LC-MS/MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATION; MOBILE PHASE; POSITIVE MODE; RIMONABANT; RISK FACTORS; STABILITY STUDIES; STANDARD DEVIATION; UPPER LIMITS;

PLASMA STABILITY;

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; BUFFER; FORMIC ACID; RIMONABANT;

ARTICLE; CALIBRATION; ELECTROSPRAY; HAIR; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA; PRIORITY JOURNAL;

CALIBRATION; CANNABINOIDS; CHROMATOGRAPHY, LIQUID; HAIR; HUMANS; PIPERIDINES; PYRAZOLES; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 49949104007     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.07.041     Document Type: Article

References (25)

1. Carai M.A., Colombo G., and Gessa G.L. Life Sci. 77 (2005) 2339
2. Rinaldi-Carmona M., Barth F., Heaulme M., Alonso R., Shire D., Congy C., Soubrie P., Breliere J.C., and Le Fur G. Life Sci. 56 (1995) 1941
3. Rinaldi-Carmona M., Barth F., Heaulme M., Shire D., Calandra B., Congy C., Martinez S., Maruani J., Neliat G., Caput D., et al. FEBS Lett. 350 (1994) 240
4. Wadman M. Nature 437 (2005) 618
5. Pi-Sunyer F.X., Aronne L.J., Heshmati H.M., Devin J., and Rosenstock J. JAMA 295 (2006) 761
6. Scheen A.J., Finer N., Hollander P., Jensen M.D., and Van Gaal L.F. Lancet 368 (2006) 1660
7. Van Gaal L.F., Rissanen A.M., Scheen A.J., Ziegler O., and Rossner S. Lancet 365 (2005) 1389
8. Despres J.P., Golay A., and Sjostrom L. N. Engl. J. Med. 353 (2005) 2121
9. Christensen R., Kristensen P.K., Bartels E.M., Bliddal H., and Astrup A. Lancet 370 (2007) 1706
10. Mitchell P.B., and Morris M.J. Lancet 370 (2007) 1671
11. Gorelick D.A., Heishman S.J., Preston K.L., Nelson R.A., Moolchan E.T., and Huestis M.A. Am. Heart J. 151 (2006) 754 e1
12. Huestis M.A., Boyd S.J., Heishman S.J., Preston K.L., Bonnet D., Le Fur G., and Gorelick D.A. Psychopharmacology (Berl.) 194 (2007) 505
13. Teixeira-Clerc F., Julien B., Grenard P., Tran Van Nhieu J., Deveaux V., Li L., Serriere-Lanneau V., Ledent C., Mallat A., and Lotersztajn S. Nat. Med. 12 (2006) 671
14. Gary-Bobo M., Elachouri G., Gallas J.F., Janiak P., Marini P., Ravinet-Trillou C., Chabbert M., Cruccioli N., Pfersdorff C., Roque C., Arnone M., Croci T., Soubrie P., Oury-Donat F., Maffrand J.P., Scatton B., Lacheretz F., Le Fur G., Herbert J.M., and Bensaid M. Hepatology 46 (2007) 122
15. Aronne L.J. Am. J. Med. 120 (2007) S26
16. Kakafika A.I., Mikhailidis D.P., Karagiannis A., and Athyros V.G. J. Clin. Pharmacol. 47 (2007) 642
17. Costa B. Br. J. Pharmacol. 150 (2007) 535
18. Calignano A., Katona I., Desarnaud F., Giuffrida A., La Rana G., Mackie K., Freund T.F., and Piomelli D. Nature 408 (2000) 96
19. Tzavara E.T., Davis R.J., Perry K.W., Li X., Salhoff C., Bymaster F.P., Witkin J.M., and Nomikos G.G. Br. J. Pharmacol. 138 (2003) 544
20. Ferrer B., Gorriti M.A., Palomino A., Gornemann I., de Diego Y., Bermudez-Silva F.J., Bilbao A., Fernandez-Espejo E., Moratalla R., Navarro M., and Rodriguez de Fonseca F. Eur. J. Pharmacol. 559 (2007) 180
21. De Vries T.J., Shaham Y., Homberg J.R., Crombag H., Schuurman K., Dieben J., Vanderschuren L.J., and Schoffelmeer A.N. Nat. Med. 7 (2001) 1151
22. European Agency for The Evaluation of Medicinal Products. Rimonabant: summary of product characteristics, 2006. http://www.emea.europa.eu/humandocs/PDFs/EPAR/acomplia/H-666-PI-en.pdf (18.07.2007).
23. Nirogi R., Kandikere V., Mudigonda K., and Ajjala D. Biomed. Chromatogr. 22 (2007) 469
24. McCulloch M., Zhou X., Xu Y., Brunell S., and Spear L. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 863 (2008) 258
25. Hsieh Y., Duncan C.J., and Brisson J.M. Anal. Chem. 79 (2007) 5668