Ceftazidime-resistant Klebsiella oxytoca producing an OXY-2-type variant from Switzerland

International Journal of Antimicrobial Agents

Volumn 32, Issue 3, 2008, Pages 278-279

  Rodríguez Martínez, José Manuel ^a   Poirel, Laurent ^a   Nordmann, Patrice ^a   Fankhauser, Carolina ^b   Francois, Patrice ^b   Schrenzel, Jacques ^b  

^a Associated French National Reference Center for Antibiotic Resistance: Carbapenemase producing Enterobacteriaceae   (France)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; AZTREONAM; CARBAPENEM; CEFEPIME; CEFTAZIDIME; CEPHAMYCIN; CHLORAMPHENICOL; GLYCINE; PIPERACILLIN PLUS TAZOBACTAM; PROLINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SERINE; TETRACYCLINE; TIMENTIN; TOBRAMYCIN; TRIMETHOPRIM;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; BACTERIAL ENDOCARDITIS; BACTERIAL STRAIN; BACTERIUM ISOLATE; BETA LACTAMASE OXY 1 GENE; BETA LACTAMASE OXY 2 GENE; DNA ISOLATION; GENE; HUMAN; KLEBSIELLA OXYTOCA; LETTER; MINIMUM INHIBITORY CONCENTRATION; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ADULT; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CEFTAZIDIME; DRUG RESISTANCE, BACTERIAL; HUMANS; KLEBSIELLA OXYTOCA; MALE; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; SWITZERLAND; VARIATION (GENETICS);

EID: 49949089864     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2008.04.002     Document Type: Letter

References (12)

1. Fournier B., Liu C.Y., Lagrange P.H., Krishnamoorthy R., and Philippon A. Point mutation in the Pribnow box, the molecular basis of β-lactamase overproduction in Klebsiella oxytoca. Antimicrob Agents Chemother 39 (1995) 1365-1368
2. Venezia R.A., Scarano F.J., Preston K.E., Steele L.M., Root T.P., Limberger R., et al. Molecular epidemiology of an SHV-5 extended-spectrum β-lactamase in Enterobacteriaceae isolated from infants in a neonatal intensive care unit. Clin Infect Dis 21 (1995) 915-923
3. OXY-2. Antimicrob Agents Chemother 40 (1996) 454-459
4. Arakawa Y., Ohta M., Kido N., Mori M., Ito H., Komatsu T., et al. Chromosomal β-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum β-lactam antibiotics. Antimicrob Agents Chemother 33 (1989) 63-70
5. Bush K., Jacoby G., and Medeiros A. A functional classification scheme for β-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother 39 (1995) 1211-1233
6. Sirot D., Labia R., Pouedras P., Chanal-Claris C., Cerceau C., and Sirot J. Inhibitor-resistant OXY-2-derived β-lactamase produced by Klebsiella oxytoca. Antimicrob Agents Chemother 42 (1998) 2184-2187
7. Mammeri H., Poirel L., and Nordmann P. In vivo selection of a chromosomally encoded β-lactamase variant conferring ceftazidime resistance in Klebsiella oxytoca. Antimicrob Agents Chemother 47 (2003) 3739-3742
8. Poirel L., Naas T., and Nordmann P. Genetic support of extended-spectrum β-lactamases. Clin Microbiol Infect 41 Suppl 1 (2008) 75-81
9. Ambler R.P., Coulson A.F., Frère J.M., Ghuysen J.M., Joris B., Forsman M., et al. A standard numbering scheme for the class A β-lactamases. Biochem J 276 (1991) 269-270
10. Poirel L., Naas T., Le Thomas I., Karim A., Bingen E., and Nordmann P. CTX-M-type extended-spectrum β-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop. Antimicrob Agents Chemother 45 (2001) 3355-3361
11. Barthélémy M., Peduzzi J., Bernard H., Tancrède C., and Labia R. Close amino acid sequence relationship between the new plasmid-mediated extended-spectrum β-lactamase MEN-1 and chromosomally encoded enzymes of Klebsiella oxytoca. Biochim Biophys Acta 1122 (1992) 15-22
12. Granier S.A., Nicolas-Chanoine M.H., Nguyen Van J.C., Leflon-Guibout V., Kitzis M.D., and Goldstein F.W. False susceptibility of Klebsiella oxytoca to some extended-spectrum cephalosporins. J Antimicrob Chemother 50 (2002) 303-304