P2X7 receptor activation amplifies lipopolysaccharide-induced vascular hyporeactivity via interleukin-1β release

Journal of Pharmacology and Experimental Therapeutics

Volumn 326, Issue 3, 2008, Pages 864-870

  Chiao, Chin Wei ^a   Tostes, Rita C ^a,b   Webb, R Clinton ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOYLBENZOYLADENOSINE TRIPHOSPHATE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; N [[3 (AMINOMETHYL)PHENYL]METHYL]ETHANIMIDAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OXIDIZED ADENOSINE TRIPHOSPHATE; PHENYLEPHRINE; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PURINERGIC P2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; ENDOTHELIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; MOUSE; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; THORACIC AORTA; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG POTENTIATION; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; SECRETION; VASCULAR DISEASE;

ANIMALS; AORTA, THORACIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; PHENYLEPHRINE; RECEPTORS, PURINERGIC P2; VASCULAR DISEASES;

EID: 49949084743     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.135350     Document Type: Article

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