Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy mice

Critical Care Medicine

Volumn 36, Issue 8, 2008, Pages 2403-2406

  Halbertsma, Feico J J ^a,b   Vaneker, Michiel ^b   Pickkers, Peter ^b   Snijdelaar, Dirk G ^b   Van Egmond, Jan ^b   Scheffer, Gert J ^b   Van Der Hoeven, Hans G ^b  

^a MÁXIMA MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Animal; Hypercapnic acidosis; Inflammation; Mechanical ventilation; PACO2; Ventilator induced lung injury

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

AMBIENT AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; ATTENUATION; BLOOD LEVEL; BLOOD PRESSURE; C57BL 6 MOUSE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERCAPNIA; INFLAMMATION; INNATE IMMUNITY; LEUKOCYTE; LUNG INJURY; LUNG PARENCHYMA; LUNG VENTILATION; MICROANALYSIS; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PH MEASUREMENT; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATORY ACIDOSIS; TIDAL VOLUME; VENTILATOR; ACIDOSIS; ANIMAL; BLOOD GAS ANALYSIS; C57BL MOUSE; IMMUNOLOGY; LUNG; METABOLISM;

ACIDOSIS; ANIMALS; BLOOD GAS ANALYSIS; CYTOKINES; LEUKOCYTES; LUNG; MICE; MICE, INBRED C57BL; RESPIRATION, ARTIFICIAL; TIDAL VOLUME;

EID: 49949084008     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318180266e     Document Type: Article

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