Superiority of Biphasic Over Monophasic Defibrillation Shocks Is Attributable to Less Intracellular Calcium Transient Heterogeneity

Journal of the American College of Cardiology

Volumn 52, Issue 10, 2008, Pages 828-835

  Hwang, Gyo Seung ^a   Tang, Liang ^c   Joung, Boyoung ^c   Morita, Norishige ^a   Hayashi, Hideki ^a   Karagueuzian, Hrayr S ^b   Weiss, James N ^b   Lin, Shien Fong ^c   Chen, Peng Sheng ^c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

electrical stimulation; polarity; resuscitation; sarcoplasmic reticulum

Indexed keywords

CALCIUM; RYANODINE; THAPSIGARGIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; DEFIBRILLATION; EPICARDIUM MAPPING; HEART DEPOLARIZATION; HEART VENTRICLE FIBRILLATION; ISOLATED HEART; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM; WAVEFORM;

ACTION POTENTIALS; ANIMALS; CALCIUM SIGNALING; ELECTRIC COUNTERSHOCK; ELECTRIC STIMULATION; MEMBRANE POTENTIALS; PERICARDIUM; RABBITS; SARCOPLASMIC RETICULUM; TIME FACTORS;

EID: 49849104769     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.05.040     Document Type: Article

References (17)

1. Jones J.L., Jones R.E., and Balasky G. Improved cardiac cell excitation with symmetrical biphasic defibrillator waveforms. Am J Physiol 253 (1987) H1418-H1424
2. Wharton J.M., Richard V.J., Murry C.E., et al. Electrophysiological effects of monophasic and biphasic stimuli in normal and infarcted dogs. Pacing Clin Electrophysiol 13 (1990) 1158-1172
3. Daubert J.P., Frazier D.W., Wolf P.D., Franz M.R., Smith W.M., and Ideker R.E. Response of relatively refractory canine myocardium to monophasic and biphasic shocks. Circulation 84 (1991) 2522-2538
4. Kao C.Y., and Hoffman B.F. Graded and decremental response in heart muscle fibers. Am J Physiol 194 (1958) 187-196
5. Dillon S.M. Optical recordings in the rabbit heart show that defibrillation strength shocks prolong the duration of depolarization and the refractory period. Circ Res 69 (1991) 842-856
6. Zhou X., Knisley S.B., Wolf P.D., Rollins D.L., Smith W.M., and Ideker R.E. Prolongation of repolarization time by electric field stimulation with monophasic and biphasic shocks in open-chest dogs. Circ Res 68 (1991) 1761-1767
7. Efimov I.R., Cheng Y., Yamanouchi Y., and Tchou P.J. Direct evidence of the role of virtual electrode-induced phase singularity in success and failure of defibrillation. J Cardiovasc Electrophysiol 11 (2000) 861-868
8. Fast V.G., and Ideker R.E. Simultaneous optical mapping of transmembrane potential and intracellular calcium in myocyte cultures. J Cardiovasc Electrophysiol 11 (2000) 547-556
9. Hwang G.-S., Hayashi H., Tang L., et al. Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles. Circulation 114 (2006) 2595-2603
10. Chen P.-S., Shibata N., Dixon E.G., et al. Activation during ventricular defibrillation in open-chest dogs. Evidence of complete cessation and regeneration of ventricular fibrillation after unsuccessful shocks. J Clin Invest 77 (1986) 810-823
11. Choi B.R., and Salama G. Simultaneous maps of optical action potentials and calcium transients in guinea-pig hearts: mechanisms underlying concordant alternans. J Physiol 529 (2000) 171-188
12. Omichi C., Lamp S.T., Lin S.F., et al. Intracellular Ca dynamics in ventricular fibrillation. Am J Physiol Heart Circ Physiol 286 (2004) H1836-H1844
13. Wang N.C., Lee M.-H., Ohara T., et al. Optical mapping of ventricular defibrillation in isolated swine right ventricles: demonstration of a postshock isoelectric window after near-threshold defibrillation shocks. Circulation 104 (2001) 227-233
14. Sato D., Shiferaw Y., Qu Z., Garfinkel A., Weiss J.N., and Karma A. Inferring the cellular origin of voltage and calcium alternans from the spatial scales of phase reversal during discordant alternans. Biophys J 92 (2007) L33-L35
15. Raman V., Pollard A.E., and Fast V.G. Shock-induced changes of Ca(i)2+ and Vm in myocyte cultures and computer model: dependence on the timing of shock application. Cardiovasc Res 73 (2007) 101-110
16. Yabe S., Smith W.M., Daubert J.P., Wolf P.D., Rollins D.L., and Ideker R.E. Conduction disturbances caused by high current density electric fields. Circ Res 66 (1990) 1190-1203
17. Antzelevitch C. Heterogeneity and cardiac arrhythmias: an overview. Heart Rhythm 4 (2007) 964-972