Effectiveness of risperidone long-acting injection in first-episode schizophrenia: In naturalistic setting

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 32, Issue 5, 2008, Pages 1231-1235

  Kim, Borah ^a   Lee, Sang Hyuk ^a   Choi, Tae Kyou ^a   Suh, ShinYoung ^a   Kim, Yong Woo ^a   Lee, EunHee ^a   Yook, Ki Hwan ^a  

^a CHA University   (South Korea)

Author keywords

First episode schizophrenia; Medication adherence; Relapse rate; Risperidone long acting injection

Indexed keywords

ALPRAZOLAM; BENZATROPINE; PROLACTIN; PROPRANOLOL; PSYCHOTROPIC AGENT; RISPERIDONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DETERIORATION; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; KAPLAN MEIER METHOD; MALE; PATIENT COMPLIANCE; PROLACTIN BLOOD LEVEL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; PSYCHOMETRY; RELAPSE; SCHIZOPHRENIA; SIDE EFFECT; SURVIVAL; TARDIVE DYSKINESIA; TREATMENT REFUSAL; TREATMENT RESPONSE;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANTIPSYCHOTIC AGENTS; CHI-SQUARE DISTRIBUTION; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISPERIDONE; SCHIZOPHRENIA; SURVIVAL ANALYSIS;

EID: 49849092027     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2008.03.012     Document Type: Article

References (26)

1. Birchwood M., Todd P., and Jackson C. Early intervention in psychosis: the critical period hypothesis. Br J Psychiatry Suppl 33 (1998) 53-59
2. Chouinard G., Ross-Chouinard A., Annable L., and Jones B. Extrapyramidal symptom rating scale(abstract). Can J Psychiatry 7 (1980) 233
3. Coldham E.L., Addington J., and Addington D. Medication adherence of individuals with first-episode psychosis. Acta Psychiatr Scand 106 (2002) 286-290
4. Davis J.M. Overview: maintenance therapy in psychiatry: I. Schizophrenia. Am J Psychiatry 132 (1975) 1237-1245
5. Drake R.J., Dunn G., Tarrier N., Bentall R.P., Haddock G., and Lewis S.W. Insight as a predictor of the outcome of first-episode nonaffective psychosis in a prospective cohort study in England. J Clin Psychiatry 68 (2007) 81-86
6. Edwards J., Maude D., Herrmann-Doig T., Wong L., Cocks J., Burnett P., et al. A service response to prolonged recovery in early psychosis. Psychiatr Serv 53 (2002) 1067-1069
7. Guy W. CGI. Clinical Global Impressions. In: Guy W. (Ed). ECDEU Assessment Manual for Psychopharmacology (1976), National Institute of Mental Health, Rockville 218-222
8. Herz M.I., Lamberti J.S., Mintz J., Scott R., O'Dell S.P., McCartan L., et al. A program for relapse prevention in schizophrenia. Arch Gen Psychiatry 57 (2000) 277-283
9. Hogarty G.E., Schooler N.R., Ulrich R., Mussare F., Ferro P., and Herron E. Fluphenazine and social therapy in the aftercare of schizophrenic patients: relapse analyses of a two-year controlled study of fluphenazine decanoate and fluphenazine hydrochloride. Arch Gen Psychiatry 36 (1979) 1283-1294
10. Kane J.M. Strategies for improving compliance in treatment of schizophrenia by using a long-acting formulation of an antipsychotic: clinical studies. J Clin Psychiatry 64 Suppl 16 (2003) 34-40
11. Kane J.M. Review of treatments that can ameliorate nonadherence in patients with schizophrenia. J Clin Psychiatry 67 Suppl 5 (2006) 9-14
12. Kasper S. First-episode schizophrenia: the importance of early intervention and subjective tolerability. J Clin Psychiatry 60 Suppl 23 (1999) 5-9
13. Kay S.R., Fiszbein A., and Opler L.A. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 13 (1980) 261-276
14. Keith S.J., Kane J.M., Turner M., Conley R.R., and Nasrallah H.A. Academic highlights: guidelines for the use of long-acting injectable atypical antipsychotics. J Clin Psychiatry 65 (2004) 120-131
15. Lehman A.F., Lieberman J.A., Dixon L.B., McGlashan T.H., Miller A.L., Perkins D.O., et al. Practice guideline for the treatment of patients with schizophrenia, second edition. Am J Psychiatry 161 Suppl 2 (2004) 1-56
16. Lieberman J.A. Pathophysiologic mechanisms in the pathogenesis and clinical course of schizophrenia. J Clin Psychiatry 60 Suppl 12 (1999) 9-12
17. Lieberman J.A., Perkins D., Belger A., Chakos M., Jarskog F., Boteva K., et al. The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches. Biol Psychiatry 50 (2001) 884-897
18. Lindenmayer J.P., Khan A., Eerdekens M., Van Hove I., and Kushner S. Long-term safety and tolerability of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder. Eur Neuropsychopharmacol 17 (2007) 138-144
19. McEvoy J.P. Risks versus benefits of different types of long-acting injectable antipsychotics. J Clin Psychiatry 67 Suppl 5 (2006) 15-18
20. Niaz O.S., and Haddad P.M. Thirty-five months experience of risperidone long-acting injection in a UK psychiatric service including a mirror-image analysis of in-patient care. Acta Psychiatr Scand 116 (2007) 36-46
21. Parellada E. Long-acting injectable risperidone in the treatment of schizophrenia in special patient populations. Psychopharmacol Bull 40 (2007) 82-100
22. Penn D.L., Waldheter E.J., Perkins D.O., Mueser K.T., and Lieberman J.A. Psychosocial treatment for first-episode psychosis: a research update. Am J Psychiatry 162 (2005) 2220-2232
23. Perkins D.O., Johnson J.L., Hamer R.M., Zipursky R.B., Keefe R.S., Centorrhino F., et al. Predictors of antipsychotic medication adherence in patients recovering from a first psychotic episode. Schizophr Res 83 (2006) 53-63
24. Sanger T.M., Lieberman J.A., Tohen M., Grundy S., Beasley Jr. C., and Tollefson G.D. Olanzapine versus haloperidol treatment in first-episode psychosis. Am J Psychiatry 156 (1999) 79-87
25. Schmauss M., Sacchetti E., Kahn J.P., and Medori R. Efficacy and safety of risperidone long-acting injectable in stable psychotic patients previously treated with oral risperidone. Int Clin Psychopharmacol 22 (2007) 85-92
26. Zygmunt A., Olfson M., Boyer C.A., and Mechanic D. Interventions to improve medication adherence in schizophrenia. Am J Psychiatry 159 (2002) 1653-1664