Brain lesion volume and capacity for consent in stroke trials: Potential regulatory barriers to the use of surrogate markers

Stroke

Volumn 39, Issue 8, 2008, Pages 2336-2340

  Dani, Krishna A ^a   McCormick, Michael T ^a   Muir, Keith W ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Clinical trials; Ethics; Informed consent; Magnetic resonance imaging

Indexed keywords

AGE DISTRIBUTION; AGED; ARTICLE; BRAIN DAMAGE; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DISEASE COURSE; DISEASE MARKER; DISEASE SEVERITY; HUMAN; INFORMED CONSENT; MAJOR CLINICAL STUDY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; STROKE; ACUTE DISEASE; ADULT; BRAIN; CLINICAL TRIAL; ETHICS; EUROPE; FEMALE; HOSPITALIZATION; MALE; PATHOLOGY; PREDICTION AND FORECASTING; STANDARD; STATISTICAL MODEL;

BIOLOGICAL MARKER;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRAIN; CLINICAL TRIALS AS TOPIC; DIFFUSION MAGNETIC RESONANCE IMAGING; EUROPE; FEMALE; HUMANS; INFORMED CONSENT; LOGISTIC MODELS; MALE; PREDICTIVE VALUE OF TESTS; SEVERITY OF ILLNESS INDEX; STROKE;

EID: 49849090971     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.107.507111     Document Type: Article

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