Quetiapine for the treatment of bipolar mania in older adults

Bipolar Disorders

Volumn 10, Issue 6, 2008, Pages 662-671

  Sajatovic, Martha ^a,c   Calabrese, Joseph R ^a   Mullen, Jamie ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ASTRAZENECA   (United Kingdom)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Antipsychotic; Bipolar mania; Clinical trial; Geriatric mania; Quetiapine

Indexed keywords

HALOPERIDOL; LITHIUM; PLACEBO; QUETIAPINE;

ADULT; AGED; AKATHISIA; ANALYSIS OF COVARIANCE; ARTICLE; ASIAN; BIPOLAR MANIA; BODY MASS; BODY WEIGHT; CAUCASIAN; CLINICAL GLOBAL IMPRESSION SCALE; CLINICAL TRIAL; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; EFFECT SIZE; ETHNIC DIFFERENCE; EXTRAPYRAMIDAL SYMPTOM; FEMALE; HEART ARREST; HEART ATRIUM FIBRILLATION; HEART MUSCLE ISCHEMIA; HISPANIC; HUMAN; HYPERTENSION; INSOMNIA; MALE; MEDICAL DECISION MAKING; MEDICAL RESEARCH; MONTGOMERY ASBERG DEPRESSION RATING SCALE; ORTHOSTATIC HYPOTENSION; OUTCOME ASSESSMENT; POSITIVE AND NEGATIVE SYNDROME SCALE; POST HOC ANALYSIS; PRIORITY JOURNAL; RATING SCALE; RIGIDITY; SCORING SYSTEM; SIDE EFFECT; SOMNOLENCE; STATISTICAL ANALYSIS; TACHYCARDIA; TARDIVE DYSKINESIA; TREATMENT OUTCOME; WEIGHT GAIN; XEROSTOMIA;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANTIPSYCHOTIC AGENTS; BIPOLAR DISORDER; DIBENZOTHIAZEPINES; DOUBLE-BLIND METHOD; DRUG EVALUATION; FEMALE; GERIATRICS; HUMANS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; TIME FACTORS; YOUNG ADULT;

EID: 49849086931     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2008.00614.x     Document Type: Article

References (51)

1. Evans DL. Bipolar disorder: Diagnostic challenges and treatment considerations. J Clin Psychiatry 2000; 61 (Suppl. 13): 26-31.
2. Bourdon KH, Rae DS, Locke BZ, Narrow WE, Regier DA. Estimating the prevalence of mental disorders in U.S. adults from the Epidemiologic Catchment Area Survey. Public Health Rep 1992; 107: 663-668.
3. American Psychiatric Association. Disease definition, natural history and course, and epidemiology. Practice Guideline for the Treatment of Patients with Bipolar Disorder, 2nd edn. Am J Psychiatry 2002; 159 (Suppl. 4): 26-31.
4. Regier DA, Myers JK, Kramer M et al. The NIMH Epidemiologic Catchment Area program. Historical context, major objectives, and study population characteristics. Arch Gen Psychiatry 1984; 41: 934-941.
5. Van Gerpen MW, Johnson JE, Winstead DK. Mania in the geriatric patient population: A review of the literature. Am J Geriatr Psychiatry 1999; 7: 77-83.
6. Yassa R, Nair NPV, Iskandar H. Late-onset bipolar disorder. Psychiatr Clin North Am 1988; 11: 117-131.
7. Bartels SJ, Forester B, Miles KM, Joyce T. Mental health service use by elderly patients with bipolar disorder and unipolar major depression. Am J Geriatr Psychiatry 2000; 8: 160-166.
8. Charney DS, Reynolds CF 3rd, Lewis L. Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry 2003; 60: 664-672.
9. Sajatovic M, Blow FC, Ignacio RV, Kales HC. Age-related modifiers of clinical presentation and health service use among veterans with bipolar disorder. Psychiatr Serv 2004; 55: 1014-1021.
10. Meeks S. Bipolar disorder in the latter half of life: Symptom presentation, global functioning and age of onset. J Affect Disord 1999; 52: 161-167.
11. Alexopoulos GS, Streim J, Carpenter D, Docherty JP. Expert Consensus Panel for using antipsychotic drugs in older patients. Using antipsychotic agents in older patients. J Clin Psychiatry 2004; 65 (Suppl. 2): 5-102.
12. Young RC, Gyulai L, Mulsant BH et al. Pharmacotherapy of bipolar disorder in old age: Review and recommendations. Am J Geriatr Psychiatry 2004; 12: 342-357.
13. Shulman KI, Rochon P, Sykora K et al. Changing prescription patterns for lithium and valproic acid in old age: Shifting practice without evidence. BMJ 2003; 326: 960-961.
14. American Psychiatric Association. Practice Guideline for the Treatment of Patients with Bipolar Disorder, 2nd edn. Am J Psychiatry 2002; 159 (4 Suppl.): 1-50.
15. Sproule BA, Hardy BG, Shulman KI. Differential pharmacokinetics of lithium in elderly patients. Drugs Aging 2000; 16: 165-177.
16. Leppik IE. Treatment of epilepsy in 3 specialized populations. Am J Manag Care 2001; 7: S221-S226.
17. Jeste D, Glazer W, Morgenstern H, Pultz J, Yeung PP. Rarity of persistent tardive dyskinesia with quetiapine treatment of psychotic disorders in the elderly. Annual Meeting of the American College of Neuropsychopharmacology, December 12-16, Acapulco, Mexico, 1999.
18. Beyer JL, Siegal A, Kennedy JS et al. Olanzapine, divalproex, and placebo treatment, non-head to head comparisons of older adult acute mania. Institute on Psychiatric Services Annual Meeting, October 10-14, Orlando, FL, 2001.
19. Sajatovic M, Gyulai L, Calabrese JR et al. Maintenance treatment outcomes in older patients with bipolar I disorder. Am J Geriatr Psychiatry 2005; 13: 305-311.
20. Bowden CL, Grunze H, Mullen J et al. A randomized, double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder. J Clin Psychiatry 2005; 66: 111-121.
21. McIntyre RS, Brecher M, Paulsson B, Huizar K, Mullen J. Quetiapine or haloperidol as monotherapy for bipolar mania-a 12-week, double-blind, randomised, parallel-group, placebo-controlled trial. Eur Neuropsychopharmacol 2005; 15: 573-585.
22. Vieta E, Mullen J, Brecher M, Paulsson B, Jones M. Quetiapine monotherapy for mania associated with bipolar disorder: Combined analysis of two international, double-blind, randomised, placebo-controlled studies. Curr Med Res Opin 2005; 21: 923-934.
23. Sachs G, Chengappa KNR, Suppes T et al. Quetiapine with lithium or divalproex for the treatment of bipolar mania: A randomized, double-blind, placebo-controlled study. Bipolar Disord 2004; 6: 213-223.
24. Yatham LN, Paulsson B, Mullen J, Vagero AM. Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania. J Clin Psychopharmacol 2004; 24: 599-606.
25. Calabrese JR, Keck PE Jr, Macfadden W et al. A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression. Am J Psychiatry 2005; 162: 1351-1360.
26. Thase ME, Macfadden W, Weisler RH et al. Efficacy of quetiapine monotherapy in bipolar I and II depression: A double-blind, placebo-controlled study (the BOLDER II study). J Clin Psychopharmacol 2006; 26: 600-609.
27. Madhusoodanan S, Brenner R, Alcantra A. Clinical experience with quetiapine in elderly patients with psychotic disorders. J Geriatr Psychiatry Neurol 2000; 13: 28-32.
28. Sicuro F. Treatment of bipolar disorder among older adults: A review of clinical cases using quetiapine. Ann Long Term Care Clin Geriatr 2003; Sept (Suppl.): 1-11.
29. Tariot PN, Salzman C, Yeung PP, Pultz J, Rak IW. Long-term use of quetiapine in elderly patients with psychotic disorders. Clin Ther 2000; 22: 1068-1084.
30. Yeung PR, Mintzer JE, Mullen JA, Sweitzer DE. Extrapyramidal symptoms in elderly outpatients treated with either quetiapine or risperidone. Annual Meeting of the American College of Neuropsychopharmacology, December 12-16, Acapulco, Mexico, 1999.
31. Jeste DV, Rockwell E, Harris MJ, Lohr JB, Lacro J. Conventional vs. newer antipsychotics in elderly patients. Am J Geriatr Psychiatry 1999; 7: 70-76.
32. Tariot PN, Salzman C, Yeung PP, Pultz J, Raniwalla J. Clinical improvement and tolerability is maintained long-term in elderly patients with psychotic disorders treated with quetiapine. Annual Meeting of the American College of Neuropsychopharmacology, December 12-16, Acapulco, Mexico, 1999.
33. McManus DQ, Arvanitis LA, Kowalcyk BB. Quetiapine, a novel antipsychotic: Experience in elderly patients with psychotic disorders. Seroquel Trial 48 Study Group. J Clin Psychiatry 1999; 60: 292-298.
34. Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 133: 429-435.
35. Spearing MK, Post RM, Leverich GS et al. Modification of the Clinical Global Impressions (CGI) scale for use in bipolar illness (BP): The CGI-BP. Psychiatry Res 1997; 73: 159-171.
36. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13: 261-276.
37. Montgomery SA, Åsberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134: 382-389.
38. Simpson GM, Angus JW. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand 1970; 212 (Suppl): 11-19.
39. Barnes TR. A rating scale for drug-induced akathisia. Br J Psychiatry 1989; 154: 672-676.
40. Cohen J. Statistical Power Analysis for the Behavioral Sciences, 2nd edn. Hillsdale, NJ: Lawrence Erlbaum Associates, Inc., 1988.
41. Madhusoodanan S, Brenner R, Araujo L, Abaza A. Efficacy of risperidone treatment for psychoses associated with schizophrenia, schizoaffective disorder, bipolar disorder, or senile dementia in 11 geriatric patients: a case series. J Clin Psychiatry 1995; 56: 514-518.
42. Madhusoodanan S, Suresh P, Brenner R, Pillai R. Experience with the atypical antipsychotics - risperidone and olanzapine in the elderly. Ann Clin Psychiatry 1999; 11: 113-118.
43. Shulman RW, Singh A, Shulman KI. Treatment of elderly institutionalized bipolar patients with clozapine. Psychopharmacol Bull 1997; 33: 113-118.
44. Frye MA, Altshuler LL, Bitran JA. Clozapine in rapid cycling bipolar disorder. J Clin Psychopharmacol 1996; 16: 87-90.
45. Sussman N. The implications of weight changes with antipsychotic treatment. J Clin Psychopharmacol 2003; 23: S21-S26.
46. Brecher M, Leong RW, Stening G, Osterling-Koskinen L, Jones AM. Quetiapine and long-term weight change: A comprehensive data review of patients with schizophrenia. J Clin Psychiatry 2007; 68: 597-603.
47. Saltz BL, Robinson DG, Woerner MG. Recognizing and managing antipsychotic drug treatment side effects in the elderly. Prim Care Companion J Clin Psychiatry 2004; 6: 14-19.
48. Zarate CA Jr. Antipsychotic drug side effect issues in bipolar manic patients. J Clin Psychiatry 2000; 61 (Suppl. 8): 52-61.
49. Sachs GS, Grossman F, Ghaemi SN, Okamoto A, Bowden CL. Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: A double-blind, placebo-controlled comparison of efficacy and safety. Am J Psychiatry 2002; 159: 1146-1154.
50. Gentile S. Extrapyramidal adverse events associated with atypical antipsychotic treatment of bipolar disorder. J Clin Psychopharmacol 2007; 27: 35-45.
51. Guy W. ECDEU Assessment Manual for Psychopharmacology. Washington, DC: US Department of Health, Education and Welfare, USGPO, 1976.