Gossypol disrupts embryo development in heifers

Journal of Dairy Science

Volumn 91, Issue 8, 2008, Pages 3015-3024

  Villasenor M ^a   Coscioni, A C ^a   Galvao K N ^a   Chebel, R C ^a   Santos, J E P ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Embryo; Gossypol; Heifer; Reproduction

Indexed keywords

BOS;

EID: 49749147166     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2007-0939     Document Type: Article

References (26)

1. AOAC. 2002. Official Methods of Analysis. 18th ed. Assoc. Off. Anal. Chem., Arlington, VA.
2. Brocas, C., R. M. Rivera, F. F. Paula-Lopes, L. R. McDowell, M. C. Calhoun, C. R. Staples, N. S. Wilkinson, A. J. Boning, P. J. Chenoweth, and P. J. Hansen. 1997. Deleterious actions of gossypol on bovine spermatozoa, oocytes, and embryos. Biol. Reprod. 57:901-907.
3. Coscioni, A. C., M. Villaseñor, K. N. Galvão, J. E. P. Santos, B. Puschner, and L. M. C. Pegoraro. 2003a. Effect of gossypol intake and plasma gossypol concentrations on follicle development and luteal function in dairy heifers. J. Dairy Sci. 86(Suppl. 1):240. (Abstr.)
4. Coscioni, A. C., M. Villaseñor, K. N. Galvão, R. Chebel, J. E. P. Santos, J. H. Kirk, B. Puschner, and L. M. C. Pegoraro. 2003b. Effect of gossypol intake on plasma and uterine gossypol concentrations and on embryo quality and development in superovulated Holstein dairy heifers. J. Dairy Sci. 86(Suppl. 1):240. (Abstr.)
5. Elrod, C. C., and W. R. Butler. 1993. Reduction of fertility and alteration of uterine pH in heifers fed excess ruminally degradable protein. J. Anim. Sci. 71:694-701.
6. Galvão, K. N., J. E. P. Santos, A. C. Coscioni, S. O. Juchem, R. C. Chebel, W. M. Sischo, and M. Viallaseñor. 2006. Embryo survival from gossypol-fed heifers after transfer to lactating cows treated with human chorionic gonadotropin. J. Dairy Sci. 89:2056-2064.
7. Gordon, I. 1994. Laboratory Production of Cattle Embryos. CAB International, Wallingford, UK.
8. Hernández-Cerón, J., F. D. Jousan, P. Soto, and P. J. Hansen. 2005. Timing of inhibitory actions of gossypol on cultured bovine embryos. J. Dairy Sci. 88:922-928.
9. Johnson, M. M., and J. P. Peters. 1993. Technical note: An improved method to quantify nonesterified fatty acids in bovine plasma. J. Anim. Sci. 71:753-756.
10. Jones, K. H., and J. A. Senft. 1985. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J. Histochem. Cytochem. 33:77-79.
11. McCaughey, K.M., E. J. DePeters, P. H. Robinson, J. E. P. Santos, S. J. Taylor, and J. W. Pareas. 2005. Impact of feeding whole Upland cottonseed, with or without cracked Pima cottonseed with increasing addition of iron sulfate, on milk and milk fat composition of lactating dairy cattle. Anim. Feed Sci. Technol. 123-124:667-685.
12. Mena, H., J. E. P. Santos, J. T. Huber, M. Tarazon, and M. C. Calhoun. 2004. The effects of varying gossypol intake from whole cottonseed and cottonseed meal on lactation and blood parameters in lactating dairy cows. J. Dairy Sci. 87:2506-2518.
13. NRC. 2001. Nutrient Requirements of Dairy Cattle. 7th rev. ed., Natl. Acad. Sci. Washington, DC.
14. Randel, R. D., S. T. Willard, S. J. Wyse, and L. N. French. 1996. Effects of diets containing free gossypol on follicular development, embryo recovery and corpus luteum function in Brangus heifer treated with bFSH. Theriogenology 45:911-922.
15. Reyes, J., J. Allen, N. Tanphaichitr, A. R. Bellvé, and D. J. Benos. 1984. Molecular Mechanism of gossypol action on lipid membranes. J. Biol. Chem. 259:9607-9615.
16. Robinson, P. H., G. Getachew, E. J. DePeters, and M. C. Calhoun. 2001. Influence of variety and storage for up to 22 days on nutrient composition and gossypol level in Pima cottonseed (Gossypium spp.). Anim. Feed Sci. Technol. 91:149-156.
17. Santos, J. E. P., R. L. A. Cerri, and R. Sartori. 2008. Nutritional management of the donor cow. Theriogenology 69:88-97.
18. Santos, J. E. P., H. Mena, J. T. Huber, and M. Tarazon. 2005. Effect of source of gossypol and iron supplementation on plasma gossypol concentrations and performance of growing Holstein steers. J. Dairy Sci. 88:3563-3574.
19. Santos, J. E. P., M. Villaseñor, E. J. DePeters, P. H. Robinson, and B. C. Baldwin. 2002. Type of cottonseed and gossypol in diets of lactating dairy cows: Lactation performance and plasma gossypol. J. Dairy Sci. 85:1491-1501.
20. Santos, J. E. P., M. Villaseñor, E. J. DePeters, P. H. Robinson, and C. H. Holmberg. 2003. Type of cottonseed and gossypol in diets of lactating dairy cows: Plasma gossypol, reproduction, and health. J. Dairy Sci. 86:892-905.
21. Stringfellow, D. A., and S. M. Seidel. 1998. Manual of the International Embryo Transfer Society. 3rd ed. Int. Embryo Transfer Soc., Savoy, IL.
22. Van Soest, P. J., J. B. Robertson, and B. A. Lewis. 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci. 74:3583-3596.
23. Van Soom, A., M. Boerjan, M. T. Ysebaert, and A. DeKruif. 1996. Cell allocation to the inner cell mass and the trophectoderm in bovine embryos cultured in two different media. Mol. Reprod. Dev. 45:171-182.
24. Velasquez-Pereira, J., C. F. Aréchiga, L. R. McDowell, P. J. Hansen, P. J. Chenoweth, M. C. Calhoun, C. A. Risco, T. R. Batra, S. N. Williams, and N. S. Wilkinson. 2002. Effects of gossypol from cottonseed meal and dietary vitamin E on the reproductive characteristics of superovulated beef heifers. J. Anim. Sci. 80:2485-2492.
25. Velasquez-Pereira, J., L. R. McDowell, C. A. Risco, D. Prichard, F. G. Martin, M. C. Calhoun, S. N. Williams, N. S. Wilkinson, and P. Ogebe. 1998. Effects on performance, tissue integrity, and metabolism of vitamin E supplementation for beef heifers fed a diet that contains gossypol. J. Anim. Sci. 76:2871-2884.
26. Zirkle, S. M., Y. C. Lin, F. C. Gwazdauskas, and R. S. Canseco. 1988. Effect of gossypol on bovine embryo development during the preimplantation period. Theriogenology 30:575-582.