Classification of childhood white matter disorders using proton MR spectroscopic imaging

American Journal of Neuroradiology

Volumn 29, Issue 7, 2008, Pages 1270-1275

  Bizzi, Alberto ^a   Castelli, G ^a   Bugiani, M ^a   Barker, P B ^c   Herskovits, E H ^b   Danesi, U ^a   Erbetta, A ^a   Moroni, I ^a   Farina, L ^a   Uziel, G ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; N ACETYLASPARTIC ACID;

ADOLESCENT; ANALYSIS OF VARIANCE; ARTICLE; BRAIN REGION; CHILD; CHILDHOOD DISEASE; DEMYELINATION; DISCRIMINANT ANALYSIS; DISEASE CLASSIFICATION; FEMALE; GENETIC DISORDER; GRAY MATTER; HUMAN; INFANT; LEUKOENCEPHALOPATHY; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; PATHOPHYSIOLOGY; PROTON NUCLEAR MAGNETIC RESONANCE; WHITE MATTER;

ADRENOLEUKODYSTROPHY; ADULT; ALEXANDER DISEASE; ASPARTIC ACID; BRAIN; CHILD; CHILD, PRESCHOOL; CHOLINE; CREATINE; DIAGNOSIS, DIFFERENTIAL; DNA MUTATIONAL ANALYSIS; DOMINANCE, CEREBRAL; FEMALE; HEREDITARY CENTRAL NERVOUS SYSTEM DEMYELINATING DISEASES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFANT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTIC ACID; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE PROTEINS; MITOCHONDRIAL DISEASES; MUSCULAR DYSTROPHIES; PELIZAEUS-MERZBACHER DISEASE; PROSPECTIVE STUDIES;

EID: 49749135519     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1106     Document Type: Article

References (17)

1. Aubourg P. The leukodystrophies: a window to myelin. Nat Genet 1993;5:105-06
2. Barkovich A, Lyon G, Ezrard P. Formation, maturation, and disorders of white matter. AJNR Am J Neuroradiol 992;13:447-61
3. van der Knaap MS, Valk J. Magnetic Resonance Myelination and Myelin Disorders. Berlin, Germany: Springer-Verlag; 2005
4. van der Knaap M, Breiter S, Naidu S. Defining and categorizing leukoencephalopathies of unknown origin: MR imaging approach. Radiology 1999;213:121-33
5. Moroni I, Bugiani M, Bizzi A, et al. Cerebral white matter involvement in children with mitochondrial encephalopathies. Neuropediatrics 2002;33:79-85
6. Barker PB, Horska A. Neuroimaging in leukodystrophies. J Child Neurol 2004;19:559-70
7. Duyn JH, Gillen J, Sobering G, et al. Multisection proton MR spectroscopic imaging of the brain. Radiology 1993;188:277-82
8. Golay X, Gillen J, van Zijl PC, et al. Scan time reduction in proton magnetic resonance spectroscopic imaging of the human brain. Magn Reson Med 2002;47:384-87
9. Bizzi A, Bugiani M, Danesi U. MR spectroscopy of inborn errors of metabolism. In: Gillard JH, Waldman AD, Barker PB, eds. Clinical MR Neuroimaging Diffusion, Perfusion and Spectroscopy. Cambridge, UK: Cambridge University Press; 2005:779-802
10. Bizzi A, Danesi U. Proton MR spectroscopy as a diagnostic tool in leukoencephalopathies. In: Uziel G, Taroni F, eds. Hereditary Leukoencephalopathies and Demyelinating Neuropathies in Children. Montrouge, France: John Libbey Eurotext; 2004;65-78
11. Soher B, van Zijl P, Duyn J, et al. Quantitative proton spectroscopic imaging of the human brain. Magn Reson Med 1996;35:356-63
12. Matalon R, Michals K, Sebesta D, et al. Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease. Am J Med Genet 1988;29:463-71
13. Horska A, Kaufmann WE, Brant LJ, et al. In vivo quantitative proton MRSI study of brain development from childhood to adolescence. J Magn Reson Imaging 2002;15:137-43
14. Kruse B, Barker PB, van Zijl PC, et al. Multislice proton magnetic resonance spectroscopic imaging in X-linked adrenoleukodystrophy. Ann Neurol 1994;36:595-608
15. Eichler FS, Itoh R, Barker PB, et al. Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience. Radiology 2002;225:245-52
16. Davie CA, Hawkins CP, Barker GJ, et al. Detection of myelin breakdown products by proton magnetic resonance spectroscopy. Lancet 1993;341:630-31
17. van der Voorn JP, Pouwels PJ, Hart AA, et al. Childhood white matter disorders: quantitative MR imaging and spectroscopy. Radiology 2006;241:510-17