메뉴 건너뛰기




Volumn 16, Issue 1, 2008, Pages 15-20

Pharmacological management of breathlessness in advanced disease

Author keywords

Analgesics; Chronic obstructive pulmonary disease; Dyspnoea; Neoplasms; Opioid; Oxygen; Palliative care; Terminal care

Indexed keywords

ALPRAZOLAM; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CLONAZEPAM; DIAZEPAM; FUROSEMIDE; HELIOX; HELIOX 28; MIDAZOLAM; MORPHINE; MORPHINE SULFATE; NARCOTIC ANALGESIC AGENT; OXYGEN; PHENOTHIAZINE DERIVATIVE; PLACEBO; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

EID: 49749131220     PISSN: 09699260     EISSN: None     Source Type: Journal    
DOI: 10.1179/096992608X291243     Document Type: Review
Times cited : (10)

References (46)
  • 1
    • 0032943991 scopus 로고    scopus 로고
    • Mechanisms, assessment, and management: A consensus statement
    • American Thoracic Society Dyspnea
    • American Thoracic Society Dyspnea. Mechanisms, assessment, and management: A consensus statement. Am J Respir Crit Care Med 1999; 159: 321-340.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 321-340
  • 2
    • 0033801482 scopus 로고    scopus 로고
    • Descriptors of breathlessness in healthy individuals: Distinct and separable constructs
    • Harver A, Mahler DA, Schwartzstein RM et al. Descriptors of breathlessness in healthy individuals: Distinct and separable constructs. Chen 2000; 118: 679-690.
    • (2000) Chen , vol.118 , pp. 679-690
    • Harver, A.1    Mahler, D.A.2    Schwartzstein, R.M.3
  • 3
    • 0033951123 scopus 로고    scopus 로고
    • Development and validation of the Cancer Dyspnoea Scale: A multidimensional, brief, self-rating scale
    • Tanaka K, Akechi T, Okuyama T et al. Development and validation of the Cancer Dyspnoea Scale: A multidimensional, brief, self-rating scale. Br J Cancer 2000; 82: 800-805.
    • (2000) Br J Cancer , vol.82 , pp. 800-805
    • Tanaka, K.1    Akechi, T.2    Okuyama, T.3
  • 4
    • 0028169032 scopus 로고
    • Chronic lung diseases and the perception of breathlessness: A clinical perspective
    • Burdon JG, Pain MC, Rubinfeld AR et al. Chronic lung diseases and the perception of breathlessness: A clinical perspective. Eur Respir J 1994; 7: 1342-1349.
    • (1994) Eur Respir J , vol.7 , pp. 1342-1349
    • Burdon, J.G.1    Pain, M.C.2    Rubinfeld, A.R.3
  • 5
    • 0035035768 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary
    • Pauwels RA, Buist AS, Calverley PM et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001; 163: 1256-1276.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 1256-1276
    • Pauwels, R.A.1    Buist, A.S.2    Calverley, P.M.3
  • 6
    • 0344393477 scopus 로고    scopus 로고
    • Morphine for management of refractory dyspnoea
    • Currow D, Abernethy A, Frith P. Morphine for management of refractory dyspnoea. BMJ 2003; 327: 1288-1289.
    • (2003) BMJ , vol.327 , pp. 1288-1289
    • Currow, D.1    Abernethy, A.2    Frith, P.3
  • 7
    • 49749089218 scopus 로고    scopus 로고
    • Leach RM. Palliative medicine and onn-malignant, end-stage respiratory disease. In: Doyle D. Hanks G. Cherny N et al (eds) Oxford Texthook of Palliative Medicine, 3rd edn. New York: Oxford University Press, 2005.
    • Leach RM. Palliative medicine and onn-malignant, end-stage respiratory disease. In: Doyle D. Hanks G. Cherny N et al (eds) Oxford Texthook of Palliative Medicine, 3rd edn. New York: Oxford University Press, 2005.
  • 8
    • 0038878880 scopus 로고
    • The effects of narcotics and antagonists upon respiration and circulation in man. A review
    • Eckenhoff JE, Oech SR. The effects of narcotics and antagonists upon respiration and circulation in man. A review. Clin Pharmacol Ther 1960; 1: 483-524.
    • (1960) Clin Pharmacol Ther , vol.1 , pp. 483-524
    • Eckenhoff, J.E.1    Oech, S.R.2
  • 9
    • 0016859569 scopus 로고
    • Diminished ventilatory response to hypoxia and hypercapnia after morphine in normal man
    • Weil JV, McCullough RE, Kline JS et al. Diminished ventilatory response to hypoxia and hypercapnia after morphine in normal man. N Engl J Med 1975; 292: 1103-1106.
    • (1975) N Engl J Med , vol.292 , pp. 1103-1106
    • Weil, J.V.1    McCullough, R.E.2    Kline, J.S.3
  • 10
    • 0017340082 scopus 로고
    • Control of breathing during methadone addiction
    • Santiago TV. Pugliese AC, Edelman NH. Control of breathing during methadone addiction. Am J Med 1977; 62: 347-354.
    • (1977) Am J Med , vol.62 , pp. 347-354
    • Santiago, T.V.1    Pugliese, A.C.2    Edelman, N.H.3
  • 11
    • 0017128093 scopus 로고
    • Effect of meperidine on occlusion pressure responses to hypercapnia and hypoxia with and Without external inspiratory resistance
    • Kryger MH, Yacoub O, Dosman J et al. Effect of meperidine on occlusion pressure responses to hypercapnia and hypoxia with and Without external inspiratory resistance. Am Rev Respir Dis 1976; 114: 333-340.
    • (1976) Am Rev Respir Dis , vol.114 , pp. 333-340
    • Kryger, M.H.1    Yacoub, O.2    Dosman, J.3
  • 12
    • 0018396422 scopus 로고
    • Effects of morphine on ventilatory response to exercise
    • Santiago TV, Johnson J, Riley DJ et al. Effects of morphine on ventilatory response to exercise. J Appl Physiol 1979; 47: 112-118.
    • (1979) J Appl Physiol , vol.47 , pp. 112-118
    • Santiago, T.V.1    Johnson, J.2    Riley, D.J.3
  • 13
    • 0036845470 scopus 로고    scopus 로고
    • A systematic review of the use of opioids in the management of dyspnoea
    • Jennings AL, Davies AN, Higgins JP et al. A systematic review of the use of opioids in the management of dyspnoea. Thorax 2002; 57: 939-944.
    • (2002) Thorax , vol.57 , pp. 939-944
    • Jennings, A.L.1    Davies, A.N.2    Higgins, J.P.3
  • 14
    • 0042377298 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea
    • Abernethy AP, Currow DC, Frith P et al. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ 2003; 327: 523-528.
    • (2003) BMJ , vol.327 , pp. 523-528
    • Abernethy, A.P.1    Currow, D.C.2    Frith, P.3
  • 15
    • 31344456197 scopus 로고    scopus 로고
    • Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnoea perception in patients with advanced cancer
    • Navigante AH. Cerchietti LCA, Castro MA et al. Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnoea perception in patients with advanced cancer. J Pain Symptom Manage 2006; 31: 38-47.
    • (2006) J Pain Symptom Manage , vol.31 , pp. 38-47
    • Navigante, A.H.1    Cerchietti, L.C.A.2    Castro, M.A.3
  • 16
    • 0033777123 scopus 로고    scopus 로고
    • Functional impairment in COPD patients: The impact of anxiety and depression
    • Kim HF, Kunik ME, Molinari VA et al. Functional impairment in COPD patients: The impact of anxiety and depression. Psychosomatics 2000; 41: 465-471.
    • (2000) Psychosomatics , vol.41 , pp. 465-471
    • Kim, H.F.1    Kunik, M.E.2    Molinari, V.A.3
  • 17
    • 0018927782 scopus 로고
    • Diazepam in the treatment of dyspnoea in the 'Pink Puffer' syndrome
    • Mitchell-Heggs P, Murphy K, Minty K et al. Diazepam in the treatment of dyspnoea in the 'Pink Puffer' syndrome. Q J Med 1980; 49: 9-20.
    • (1980) Q J Med , vol.49 , pp. 9-20
    • Mitchell-Heggs, P.1    Murphy, K.2    Minty, K.3
  • 18
    • 0019840036 scopus 로고
    • Drug treatment of breathlessness: Contrasting effects of diazepam and promethazine in pink puffers
    • Woodcock AA, Gross ER, Geddes DM. Drug treatment of breathlessness: contrasting effects of diazepam and promethazine in pink puffers. BMJ 1981; 283: 343-346.
    • (1981) BMJ , vol.283 , pp. 343-346
    • Woodcock, A.A.1    Gross, E.R.2    Geddes, D.M.3
  • 19
    • 0020563886 scopus 로고
    • The response of the breathless patient treated with diazepam
    • Sen D, Jones G, Leggat PO. The response of the breathless patient treated with diazepam. Br J Clin Pract 1983; 37: 232-233.
    • (1983) Br J Clin Pract , vol.37 , pp. 232-233
    • Sen, D.1    Jones, G.2    Leggat, P.O.3
  • 20
    • 0022996163 scopus 로고
    • Effect of alprazolam on exercise and dyspnea in patients with chronic obstructive pulmonary disease
    • Man GC, Hsu K, Sproule BJ. Effect of alprazolam on exercise and dyspnea in patients with chronic obstructive pulmonary disease. Chest 1986; 90: 832-836.
    • (1986) Chest , vol.90 , pp. 832-836
    • Man, G.C.1    Hsu, K.2    Sproule, B.J.3
  • 21
    • 0024535282 scopus 로고
    • Effects of alprazolam on respiratory drive, anxiety, and dyspnea in chronic airflow obstruction: A case study
    • Greene JG, Pucino E, Carlson JD et al. Effects of alprazolam on respiratory drive, anxiety, and dyspnea in chronic airflow obstruction: a case study. Pharmacothery 1989: 9: 34-38.
    • (1989) Pharmacothery , vol.9 , pp. 34-38
    • Greene, J.G.1    Pucino, E.2    Carlson, J.D.3
  • 22
    • 0024524291 scopus 로고
    • Buspirone. an anxiolytic drug that stimulates respiration
    • Garner SJ, Eldridge FL, Wagner PG et al. Buspirone. an anxiolytic drug that stimulates respiration. Am Rev Respir Dis 1989; 139: 946-950.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 946-950
    • Garner, S.J.1    Eldridge, F.L.2    Wagner, P.G.3
  • 24
    • 0027482124 scopus 로고
    • Buspirone effect on breathlessness and exercise performance in patients with chronic obstructive pulmonary disease
    • Argyropoulou P, Patakas D, Koukou A et al. Buspirone effect on breathlessness and exercise performance in patients with chronic obstructive pulmonary disease. Respiration 1993; 60: 216-220.
    • (1993) Respiration , vol.60 , pp. 216-220
    • Argyropoulou, P.1    Patakas, D.2    Koukou, A.3
  • 25
    • 0027450509 scopus 로고
    • Effect of buspirone on anxiety levels and exercise tolerance in patients with chronic airflow obstruction and mild anxiety
    • Singh NP, Despars JA, Stansbury DW et al. Effect of buspirone on anxiety levels and exercise tolerance in patients with chronic airflow obstruction and mild anxiety. Chest 1993; 103: 800-804
    • (1993) Chest , vol.103 , pp. 800-804
    • Singh, N.P.1    Despars, J.A.2    Stansbury, D.W.3
  • 26
    • 0029156410 scopus 로고
    • Sertraline for chronic obstructive pulmonary disease and comorbid anxiety and mood disorders
    • Papp LA, Weiss JR, Greenberg HE et al. Sertraline for chronic obstructive pulmonary disease and comorbid anxiety and mood disorders. Am J Psychiatry 1995; 152: 1531.
    • (1995) Am J Psychiatry , vol.152 , pp. 1531
    • Papp, L.A.1    Weiss, J.R.2    Greenberg, H.E.3
  • 27
    • 0031944471 scopus 로고    scopus 로고
    • Sertraline effects on dyspnea in patients with obstructive airways disease
    • Smoller JV, Pollack MH, Systrom D et al. Sertraline effects on dyspnea in patients with obstructive airways disease. Psychosomatics 1998; 39: 24-29.
    • (1998) Psychosomatics , vol.39 , pp. 24-29
    • Smoller, J.V.1    Pollack, M.H.2    Systrom, D.3
  • 28
    • 0014541840 scopus 로고
    • Disproportionately severe breathlessness in chronic bronchitis
    • Burns BH, Howell JB. Disproportionately severe breathlessness in chronic bronchitis. Q J Med 1969; 38: 277-294.
    • (1969) Q J Med , vol.38 , pp. 277-294
    • Burns, B.H.1    Howell, J.B.2
  • 29
  • 30
    • 0025289239 scopus 로고
    • Inhaled frusemide inhibits cough induced by low chloride content solutions but not by capsaicin
    • Ventresca PG, Nichol GM, Barnes PJ et al. Inhaled frusemide inhibits cough induced by low chloride content solutions but not by capsaicin. Am Rev Respir Dis 1990; 142: 143-146.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 143-146
    • Ventresca, P.G.1    Nichol, G.M.2    Barnes, P.J.3
  • 31
    • 0023785166 scopus 로고    scopus 로고
    • Prevention of exercise-induced bionchoconstriction by inhaled frusemide
    • Bianco S, Vaghi A, Robuschi M et al. Prevention of exercise-induced bionchoconstriction by inhaled frusemide. Lancet 1998; 2 252-255.
    • (1998) Lancet , vol.2 , pp. 252-255
    • Bianco, S.1    Vaghi, A.2    Robuschi, M.3
  • 32
    • 0024455058 scopus 로고
    • Protective effect of inhaled frusemide on allergen-induced early and late asthmatic reactions
    • Bianco S, Pieroni MG, Refini RM et al. Protective effect of inhaled frusemide on allergen-induced early and late asthmatic reactions. N Engl J Med 1989; 321: 1069-1073.
    • (1989) N Engl J Med , vol.321 , pp. 1069-1073
    • Bianco, S.1    Pieroni, M.G.2    Refini, R.M.3
  • 33
    • 0024773093 scopus 로고
    • Inhaled frusemide is highly effective in preventing ultrasonically nebulised water bronchoconstriction
    • Robuschi M, Gambaro G, Spagnotto S et al. Inhaled frusemide is highly effective in preventing ultrasonically nebulised water bronchoconstriction. Pulm Pharmacol 1989; 1: 187-191.
    • (1989) Pulm Pharmacol , vol.1 , pp. 187-191
    • Robuschi, M.1    Gambaro, G.2    Spagnotto, S.3
  • 35
    • 0034086538 scopus 로고    scopus 로고
    • Inhaled frusemide greatly alleviates the sensation of experimentally induced dyspnea
    • Nishino T, Ide T, Sudo T et al. Inhaled frusemide greatly alleviates the sensation of experimentally induced dyspnea. Am J Respir Crit Care Med 2000; 161: 1963-1967.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1963-1967
    • Nishino, T.1    Ide, T.2    Sudo, T.3
  • 36
    • 2142645897 scopus 로고    scopus 로고
    • Effects of inhaled frusemide on exertional dyspnea in chronic obstructive pulmonary disease
    • Ong KC, Kor AC, Chong WE et al. Effects of inhaled frusemide on exertional dyspnea in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004; 169: 1028-1033.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 1028-1033
    • Ong, K.C.1    Kor, A.C.2    Chong, W.E.3
  • 37
    • 0034086538 scopus 로고    scopus 로고
    • Inhaled frusemide greatly alleviates the sensation of experimentally induced dyspnea
    • Nishiho T, Ide T, Sudo T et al. Inhaled frusemide greatly alleviates the sensation of experimentally induced dyspnea. Am J Respir Crit Care Med 2000; 161: 1963-1967.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1963-1967
    • Nishiho, T.1    Ide, T.2    Sudo, T.3
  • 38
    • 1342344003 scopus 로고    scopus 로고
    • A double-blind, randomised, controlled Phase II trial of Heliox 28 gas mixture in lung cancer patients with dyspnoea on exertion
    • Ahmedzai SH, Laude E, Robertson A et al. A double-blind, randomised, controlled Phase II trial of Heliox 28 gas mixture in lung cancer patients with dyspnoea on exertion. Br J Cancer 2004; 90: 366-371.
    • (2004) Br J Cancer , vol.90 , pp. 366-371
    • Ahmedzai, S.H.1    Laude, E.2    Robertson, A.3
  • 39
    • 0346505458 scopus 로고    scopus 로고
    • The use of oxygen in the palliation of breathlessness. A report of the expert working group of the Scientific Committee of the Association of Palliative Medicine
    • Booth S, Wade R, Johnson M et al. The use of oxygen in the palliation of breathlessness. A report of the expert working group of the Scientific Committee of the Association of Palliative Medicine. Respir Med 2004; 98: 66-77.
    • (2004) Respir Med , vol.98 , pp. 66-77
    • Booth, S.1    Wade, R.2    Johnson, M.3
  • 40
    • 0026758516 scopus 로고
    • Symptomatic benefit of supplemental oxygen in hypoxemic patients with terminal cancer: The use of the N of 1 randomized controlled trial
    • Bruera E, Schoeller T, MacEachern T. Symptomatic benefit of supplemental oxygen in hypoxemic patients with terminal cancer: The use of the N of 1 randomized controlled trial. J Pain Symptom Manage 1992; 7: 365-368.
    • (1992) J Pain Symptom Manage , vol.7 , pp. 365-368
    • Bruera, E.1    Schoeller, T.2    MacEachern, T.3
  • 41
    • 0033738825 scopus 로고    scopus 로고
    • Appropriateness of domiciliary oxygen delivery
    • Guyatt GH, McKim DA, Austin P et al. Appropriateness of domiciliary oxygen delivery. Chest 2000; 118: 1303-1308
    • (2000) Chest , vol.118 , pp. 1303-1308
    • Guyatt, G.H.1    McKim, D.A.2    Austin, P.3
  • 42
    • 15944406084 scopus 로고    scopus 로고
    • Prescribing palliative oxygen: A clinician survey of expected benefit and patterns of use
    • Abernethy AP, Currow DC, Frith P et al. Prescribing palliative oxygen: A clinician survey of expected benefit and patterns of use. Palliat Med 2005; 19: 168-170.
    • (2005) Palliat Med , vol.19 , pp. 168-170
    • Abernethy, A.P.1    Currow, D.C.2    Frith, P.3
  • 43
    • 12344293337 scopus 로고    scopus 로고
    • Physician practices for prescribing supplemental oxygen in the palliative care setting
    • Stringer E, McParland C, Hernandez P. Physician practices for prescribing supplemental oxygen in the palliative care setting. J Palliat Care 2004; 20: 303-307.
    • (2004) J Palliat Care , vol.20 , pp. 303-307
    • Stringer, E.1    McParland, C.2    Hernandez, P.3
  • 45
    • 34447637082 scopus 로고    scopus 로고
    • Oxygen use - patients define symptomatic benefit discerningly
    • Currow DC, Fazekas B, Abernethy AP, Oxygen use - patients define symptomatic benefit discerningly. J Pain Symptom Manage 2007; 34: 113-114.
    • (2007) J Pain Symptom Manage , vol.34 , pp. 113-114
    • Currow, D.C.1    Fazekas, B.2    Abernethy, A.P.3
  • 46
    • 0035136115 scopus 로고    scopus 로고
    • The shuttle walking test: A reproducible method for evaluating the impact of shortness of breath on functional capacity in patients with advanced cancer
    • Booth S, Adams L. The shuttle walking test: A reproducible method for evaluating the impact of shortness of breath on functional capacity in patients with advanced cancer. Thorax 2001; 56: 146-150
    • (2001) Thorax , vol.56 , pp. 146-150
    • Booth, S.1    Adams, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.