Role of α2-adrenoceptors in enhancement of antinociceptive effect in diabetic mice

European Journal of Pharmacology

Volumn 592, Issue 1-3, 2008, Pages 62-66

  Omiya, Yuji ^a   Yuzurihara, Mitsutoshi ^a   Suzuki, Yasuyuki ^a   Kase, Yoshio ^a   Kono, Toru ^b  

^a TSUMURA AND CO   (Japan)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

2 adrenoceptor; Antinociception; Descending pain inhibitory system; Diabetes; Spinal cord

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; METHOXAMINE; METIROSINE; NORADRENALIN; RAUWOLSCINE; TYROSINE 3 MONOOXYGENASE; YOHIMBINE; ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANALGESIC AGENT; DIAGNOSTIC AGENT; ENZYME INHIBITOR; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; DRUG BINDING SITE; DRUG POTENCY; MALE; MOUSE; NEUROCHEMISTRY; NEUROPATHIC PAIN; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SEROTONINERGIC SYSTEM; SPINAL CORD; STREPTOZOCIN DIABETES; TISSUE LEVEL; ANIMAL; CELL MEMBRANE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; PAIN ASSESSMENT; PATHOLOGY; PHYSIOLOGY; PRESSURE;

ADRENERGIC ALPHA-AGONISTS; ALPHA-METHYLTYROSINE; ANALGESICS; ANIMALS; CELL MEMBRANE; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; INJECTIONS, SPINAL; MALE; METHOXAMINE; MICE; NOREPINEPHRINE; PAIN MEASUREMENT; PRESSURE; RECEPTORS, ADRENERGIC, ALPHA-2; SEROTONIN; SPINAL CORD; SYMPATHOLYTICS; TYROSINE 3-MONOOXYGENASE; YOHIMBINE;

EID: 49749118628     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.087     Document Type: Article

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