Physiological effects of human muscle-derived stem cell implantation on urethral smooth muscle function

International Urogynecology Journal

Volumn 19, Issue 9, 2008, Pages 1229-1234

  Furuta, Akira ^a,b   Jankowski, Ron J ^c   Pruchnic, Ryan ^c   Egawa, Shin ^b   Yoshimura, Naoki ^a   Chancellor, Michael B ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Cook Myosite ^*  (United States)

Author keywords

Bladder; Cellular therapy; Muscle; Stem cell; Urethra; Urinary incontinence

Indexed keywords

CARBACHOL; HEXAMETHONIUM; PHENYLEPHRINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; EFFERENT NERVE; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; HUMAN CELL; MUSCLE CELL; MUSCLE FUNCTION; NERVE BLOCK; NERVE TRANSECTION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PUDENDAL NERVE; RAT; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTION; STEM CELL TRANSPLANTATION; URETHRA DISEASE;

EID: 49749118610     PISSN: 09373462     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00192-008-0608-9     Document Type: Article

References (21)

1. Furuta A, Jankowski RJ, Pruchnic R, Yoshimura N, Chancellor MB (2007) The potential of muscle-derived stem cells for stress urinary incontinence. Expert Opin Biol Ther 7:1483-1486
2. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD et al (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147
3. Carr LK, Steele D, Steele S, Wagner D, Pruchnic R, Jankowski RJ et al (2007) University of Toronto clinical trial of muscle-derived stem cell injection in women with stress urinary incontinence. J Urol 177:439
4. Qu Z, Balkir L, van Deutekom JC, Robbins PD, Pruchnic R, Huard J (1998) Development of approaches to improve cell survival in myoblast transfer therapy. J Cell Biol 142:1257-1267
5. Qu-Petersen Z, Deasy B, Jankowski R, Ikezawa M, Cummins J, Pruchnic R et al (2002) Identification of a novel population of muscle stem cells in mice: Potential for muscle regeneration. J Cell Biol 157:851-864
6. Huard J, Yokoyama T, Pruchnic R, Qu Z, Li Y, Lee JY et al (2002) Muscle-derived cell-mediated ex vivo gene therapy for urological dysfunction. Gene Ther 9:1617-1626
7. Yokoyama T, Yoshimura N, Dhir R, Qu Z, Fraser MO, Kumon H et al (2001) Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence. J Urol 165:271-276
8. Cannon TW, Lee JY, Somogyi G, Pruchnic R, Smith CP, Huard J et al (2003) Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra. Urology 62:958-963
9. Lee JY, Cannon TW, Pruchnic R, Fraser MO, Huard J, Chancellor MB (2003) The effects of periurethral muscle-derived stem cell injection on leak point pressure in a rat model of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 14:31-37 discussion 37
10. Chermansky CJ, Tarin T, Kwon DD, Jankowski RJ, Cannon TW, de Groat WC et al (2004) Intraurethral muscle-derived cell injections increase leak point pressure in a rat model of intrinsic sphincter deficiency. Urology 63:780-785
11. Carr LK, Steele D, Steele S, Wagner D, Pruchnic R, Jankowski R et al (2006) Single institution clinical trial of muscle-derived cell injection to treat stress urinary incontinence. J Urol 175:414
12. Kim YT, Kim DK, Jankowski RJ, Pruchnic R, Usiene I, de Miguel F et al (2007) Human muscle-derived cell injection in a rat model of stress urinary incontinence. Muscle Nerve 36:391-393
13. Furuta A, Jankowski RJ, Honda M, Pruchnic R, Yoshimura N, Chancellor MB (2007) State of the art of where we are at using stem cells for stress urinary incontinence. Neurourol Urodyn 26:966-971
14. Manzo J, Vazquez MI, Cruz MR, Hernandez ME, Carrillo P, Pacheco P (2000) Fertility ratio in male rats: Effects after denervation of two pelvic floor muscles. Physiol Behav 68:611-618
15. Conway DA, Kamo I, Yoshimura N, Chancellor MB, Cannon TW (2005) Comparison of leak point pressure methods in an animal model of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 16:359-363
16. Kwon D, Kim Y, Pruchnic R, Jankowski R, Usiene I, de Miguel F et al (2006) Periurethral cellular injection: Comparison of muscle-derived progenitor cells and fibroblasts with regard to efficacy and tissue contractility in an animal model of stress urinary incontinence. Urology 68:449-454
17. Peng CW, Chen JJ, Chang HY, de Groat WC, Cheng CL (2006) External urethral sphincter activity in a rat model of pudendal nerve injury. Neurourol Urodyn 25:388-396
18. de Groat WC (2006) Integrative control of the lower urinary tract: preclinical perspective. Br J Pharmacol 147(Suppl 2):S25-S40
19. Harrison SC, Hunnam GR, Farman P, Ferguson DR, Doyle PT (1987) Bladder instability and denervation in patients with bladder outflow obstruction. Br J Urol 60:519-522
20. Yokoyama O, Nagano K, Kawaguchi K, Hisazumi H (1991) The response of the detrusor muscle to acetylcholine in patients with infravesical obstruction. Urol Res 19:117-121
21. German K, Bedwani J, Davies J, Brading AF, Stephenson TP (1995) Physiological and morphometric studies into the pathophysiology of detrusor hyperreflexia in neuropathic patients. J Urol 153:1678-1683