Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: A yeast two-hybrid approach

Proteomics

Volumn 8, Issue 15, 2008, Pages 3071-3081

  Thalappilly, Subhash ^a,b   Suliman, Muhtadi ^a,b   Gayet, Odile ^a,b   Soubeyran, Philippe ^a,b   Hermant, Aurélie ^a   Lecine, Patrick ^a   Iovanna, Juan L ^a,b   Dusetti, Nelson J ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Cellular functional compartments; Pancreatic ductal adenocarcinoma; Scaffold proteins; SH3 domain; Sos recruitment system

Indexed keywords

ADAPTOR PROTEIN; PROTEIN SH3; SCAFFOLD PROTEIN; UBIQUITIN;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; GENE AMPLIFICATION; GENETIC COMPATIBILITY; HOMEOSTASIS; HYBRID; IMMUNOPRECIPITATION; INTERACTOME; MICROARRAY ANALYSIS; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; WESTERN BLOTTING; YEAST;

BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEINS; PROTEOMICS; SRC HOMOLOGY DOMAINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 49749103949     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200701157     Document Type: Article

References (34)

1. Kleeff, J., Michalski, C., Friess, H., Buchler, M. W., Pancreatic cancer: From bench to 5-year survival. Pancreas 2006, 33, 111-118.
2. Hezel, A. F., Kimmelman, A. C., Stanger, B. Z., Bardeesy, N., Depinho, R. A., Genetics and biology of pancreatic ductal adenocarcinoma. Genes. Dev. 2006, 20, 1218-1249.
3. Moskaluk, C. A., Hruban, R. H., Kern, S. E., p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma. Cancer Res. 1997, 57, 2140-2143.
4. Hruban, R. H., Goggins, M., Parsons, J., Kern, S. E., Progression model for pancreatic cancer. Clin. Cancer Res. 2000, 6, 2969-2972.
5. Bardeesy, N., DePinho, R. A., Pancreatic cancer biology and genetics. Nat. Rev. Cancer 2002, 2, 897-909.
6. Gironella, M., Seux, M., Xie, M. J., Cano, C. et al., Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc. Natl. Acad. Sci. USA 2007, 104, 16170-16175.
7. Ekman, D., Light, S., Bjorklund, A. K., Elofsson, A., What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae? Genome Biol. 2006, 7, R45.
8. Mayer, B. J., SH3 domains: Complexity in moderation. J. Cell. Sci. 2001, 114, 1253-1263.
9. McPherson, P. S., Regulatory role of SH3 domain-mediated protein-protein interactions in synaptic vesicle endocytosis. Cell Signal. 1999, 11, 229-238.
10. Vidal, M., Gigoux, V., Garbay, C., SH2 and SH3 domains as targets for anti-proliferative agents. Crit. Rev. Oncol. Hematol. 2001, 40, 175-186.
11. Walhout, A. J., Vidal, M., High-throughput yeast two-hybrid assays for large-scale protein interaction mapping. Methods 2001, 24, 297-306.
12. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J. et al., Gapped BLASTand PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 1997, 25, 3389-3402.
13. Orr-Weaver, T. L., Szostak, J. W., Yeast recombination: The association between double-strand gap repair and crossing-over. Proc. Natl. Acad. Sci. USA 1983, 80, 4417-4421.
14. Wu, C. H., Apweiler, R., Bairoch, A., Natale, D. A. et al., The Universal Protein Resource (UniProt): An expanding universe of protein information. Nucleic Acids Res. 2006, 34, D187-D191.
15. Obenauer, J. C., Cantley, L. C., Yaffe, M. B., Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res. 2003, 31, 3635-3641.
16. Morton, C. J., Campbell, I. D., SH3 domains. Molecular 'Velcro'. Curr. Biol. 1994, 4, 615-617.
17. Finn, R. D., Mistry, J., Schuster-Bockler, B., Griffiths-Jones, S. et al., Pfam: Clans, web tools and services. Nucleic Acids Res. 2006, 34, D247-D251.
18. Schuler, G. D., Pieces of the puzzle: Expressed sequence tags and the catalog of human genes. J. Mol. Med. 1997, 75, 694-698.
19. Aronheim, A., Zandi, E., Hennemann, H., Elledge, S. J., Karin, M., Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions. Mol. Cell. Biol. 1997, 17, 3094-3102.
20. Walhout, A. J., Sordella, R., Lu, X., Hartley, J. L. et al., Protein interaction mapping in C. elegans using proteins involved in vulval development. Science 2000, 287, 116-122.
21. Orchard, S., Salwinski, L., Kerrien, S., Montecchi-Palazzi, L. et al., The minimum information required for reporting a molecular interaction experiment (MIMIx). Nat. Biotechnol. 2007, 25, 894-898.
22. Mitsui, K., Matsumoto, A., Ohtsuka, S., Ohtsubo, M., Yoshimura, A., Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1. Biochem. Biophys. Res. Commun. 1999, 264, 457-464.
23. Kimber, W. A., Deak, M., Prescott, A. R., Alessi, D. R., Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1. Biochem. J. 2003, 376, 525-535.
24. Marty, C., Browning, D. D., Ye, R. D., Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. Mol. Cell. Biol. 2003, 23, 3847-3858.
25. Jimenez, A., Pelto-Huikko, M., Gustafsson, J. A., Miranda-Vizuete, A., Characterization of human thioredoxin-like-1: Potential involvement in the cellular response against glucose deprivation. FEBS Lett. 2006, 580, 960-967.
26. Coll, P. M., Rincon, S. A., Izquierdo, R. A., Perez, P., Hob3p, the fission yeast ortholog of human BIN3, localizes Cdc42p to the division site and regulates cytokinesis. EMBO J. 2007, 26, 1865-1877.
27. Skoufias, D. A., Andreassen, P. R., Lacroix, F. B., Wilson, L., Margolis, R. L., Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints. Proc. Natl. Acad. Sci. USA 2001, 98, 4492-4497.
28. Uchiyama, K., Jokitalo, E., Kano, F., Murata, M. et al., VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J. Cell Biol. 2002, 159, 855-866.
29. Swat, W., Fujikawa, K., The Vav family: At the crossroads of signaling pathways. Immunol. Res. 2005, 32, 259-265.
30. Franco, M., Furstoss, O., Simon, V., Benistant, C. et al., The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. Mol. Cell. Biol. 2006, 26, 1932-1947.
31. Kawakatsu, T., Ogita, H., Fukuhara, T., Fukuyama, T. et al., Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. J. Biol. Chem. 2005, 280, 4940-4947.
32. Fernandez-Zapico, M. E., Gonzalez-Paz, N. C., Weiss, E., Savoy, D. N. et al., Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell 2005, 7, 39-49.
33. Hayes, G. M., Carrigan, P. E., Beck, A. M., Miller, L. J., Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma. Cancer Res. 2006, 66, 3819-3827.
34. Parrish, J. R., Gulyas, K. D., Finley, R. L., Jr., Yeast two-hybrid contributions to interactome mapping. Curr. Opin. Biotechnol. 2006, 17, 387-393.