Points of control exerted along the macrophage-endothelial cell-polymorphonuclear neutrophil axis by PECAM-1 in the innate immune response of acute colonic inflammation

Journal of Immunology

Volumn 181, Issue 3, 2008, Pages 2145-2154

  Sugimoto, Naohito ^a,b   Rui, Tao ^a   Yang, Min ^a   Bharwani, Sulaiman ^a   Handa, Osamu ^a,b   Yoshida, Norimasa ^b   Yoshikawa, Toshikazu ^b   Kvietys, Peter R ^a  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KERATINOCYTE DERIVED CHEMOKINE; TRINITROBENZENESULFONIC ACID;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CHEMOTAXIS; CHIMERA; COLITIS; COLON LAVAGE; CONTROLLED STUDY; DISEASE CONTROL; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; GENE CONSTRUCT; HEMATOPOIETIC CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROVOCATION TEST; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; CHEMICALLY INDUCED DISORDER; CYTOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR MIMICRY; MOUSE MUTANT; PATHOLOGY;

ACUTE DISEASE; ANIMALS; ANTIGENS, CD31; CELL ADHESION; CELL MOVEMENT; CELLS, CULTURED; COLITIS; ENDOTHELIAL CELLS; IMMUNITY, NATURAL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR MIMICRY; NEUTROPHILS; TRINITROBENZENESULFONIC ACID;

EID: 49649121520     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.3.2145     Document Type: Article

References (42)

1. Nourshargh, S., F. Krombach, and E. Dejana. 2006. The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues. J. Leukocyte Biol. 80: 714-718.
2. Muller, W. A. 2003. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol. 24: 327-334.
3. Ilan, N., and J. A. Madri. 2003. PECAM-1: old friend, new partners. Curr. Opin. Cell Biol. 15: 515-524.
4. Albelda, S. M., K. C. Lau, P. Chien Z. Y. Huang, E. Arguiris, A. Bohen, J. Sun, J. A. Billet, M. Christofidou-Solomidou, Z. K. Indik, and A. D. Schrieber. 2004. Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcγ receptor function. Am. J. Respir. Cell Mol. Biol. 31: 246-255.
5. Graesser, D., A. Solowiej, M. Bruckner, E. Osterweil, A. Juedes, S. Davis, N. H. Ruddle, B. Engelhardt, and J. A. Madri. 2002. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J. Clin. Invest. 109: 383-392.
6. Wong, M. X., J. D. Hayball, P. M. Hogarth, and D. E. Jackson. 2005. The inhibitory co-receptor, PECAM-1 provides a protective effect in suppression of collagen-induced arthritis. J. Clin. Immunol. 25: 19-28.
7. Wong, M. X., D. Roberts, P. A. Bartley, and D. E. Jackson. 2002. Absence of platelet endothelial cell adhesion molecule-1 (CD31) leads to increased severity of local and systemic IgE-mediated anaphylaxis and modulation of mast cell activation. J. Immunol. 168: 6455-6462.
8. Wilkinson, R., A. B. Lyons, D. Roberts, M. X. Wong, P. A. Bartley, and D. E. Jackson. 2002. Platelet endothelial cell adhesion molecule-1 (PECAM-1/ CD31) acts as a regulator of B-cell development, B-cell antigen receptor(BCR)- mediated activation, and autoimmune disease. Blood 100: 184-193.
9. O'Brien, C. D., P. Lim, J. Sun, and S. M. Albelda. 2003. PECAM-1-dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization. Blood 101: 2816-2825.
10. Elias, C. G., III, J. P. Spellberg, B. Karan-Tamir, C. H. Lin, Y. J. Wang, P. J. McKenna, W. A. Muller, M. M. Zukowsk, and D. P. Andrew. 1998. Ligation of CD31/PECAM-1 modulates the function of lymphocytes, monocytes and neutrophils. Eur. J. Immunol. 28: 1948-1958.
11. Berman, M. E., and W. A. Muller. 1995. Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increases binding capacity of leukocyte CR3 (CD11b/CD18). J. Immunol. 154: 299-307.
12. Schenkel, A. R., T. W. Chew, E. Chlipala, M. W. Harbord, and W. A. Mulle. 2006. Different susceptibilities of PECAM-deficient mouse strains to spontaneous idiopathic pneumonitis. Exp. Mol. Pathol. 81: 23-30.
13. Schenkel, A. R., T. W. Chew, and W. A. Muller. 2004. Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains. J. Immunol. 173: 6403-6408.
14. Cobrin, G. M., and M. T. Abreu. 2005. Defects in mucosal immunity leading to Crohn's disease. Immunol. Rev. 206: 277-295.
15. Nathan, C. 2006. Neutrophils and immunity: challenges and opportunities. Nat. Rev. Immunol. 6: 173-182.
16. Elson, C. O., Y. Cong, V. J. McCracken., R. A. Dimmitt, R. G. Lorenz, and C. T. Weaver. 2005. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol. Rev. 206: 260-276.
17. Borghesi, L., and C. Milcarek. 2007. Innate versus adaptive immunity: a paradigm past its prime? Cancer Res. 67: 3989-3993.
18. Strober, W., I. J. Fuss, and R. S. Blumberg. 2002. The immunology of mucosal models of inflammation. Annu. Rev. Immunol. 20: 495-549.
19. Kanai, T., M. Watanabe, A. Okazawa, T. Sato, M. Yamazaki, S. Okamoto, H. Ishii, T. Totsuka, R. Iiyama, and R. Okamoto. 2001. Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease. Gastroenterology 121: 875-888.
20. McCafferty, D. M., M. Miampamba, E. Sihota, K. A. Sharkey, and P. Kubes. 1999. Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice. Gut 45: 864-873.
21. Palmen, M. J., C. D. Dijkstra, M. B. van der Ende, A. S. Pena, and E. P. van Rees. 1995. Anti-CD11b/CD18 antibodies reduce inflammation in acute colitis in rats. Clin. Exp. Immunol. 101: 351-356.
22. Santucci, L., M. Agostini, S. Bruscoli, A. Mencarelli, S. Ronchetti, E. Ayroldi, A. Morelli, M. Baldoni, and C. Riccardi. 2007. GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice. Gut 56: 52-60.
23. 1 in TNBS-induced colitis. Immunity 17: 769-780.
24. Razavi, H. M., L. F. Wang, S. Weicker, M. Rohan, C. Law, D. G. McCormack, and S. Mehta. 2004. Pulmonary neutrophil infiltration in murine sepsis: role of inducible nitric oxide synthase. Am. J. Respir. Crit. Care Med. 170: 227-233.
25. Rui, T., G. Cepinskas, Q. Feng, Y. S. Ho, and P. R. Kvietys. 2001. Cardiac myocytes exposed to anoxia-reoxygenation promote neutrophil transendothelial migration. Am. J. Physiol. 281: H440-H447.
26. Keshavarzian, A., R. D. Fusunyan, M. Jacyno, D. Winship, R. P. MacDermott, and I. R. Sanderson. 1999. Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am. J. Gastroenterol. 94: 704-712.
27. Rui, T., Q. Feng, M. Lei, T. Peng, J. Zhang, M. Xu, E. D. Abel, A. Xenocostas, and P. R. Kvietys. 2005. Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1. Cardiovasc. Res. 65: 719-727.
28. Lush, C. W., G. Cepinskas, and P. R. Kvietys. 2003. Regulation of intestinal nuclear factor-κB activity and E-selectin expression during sepsis: a role for peroxynitrite. Gastroenterology 124: 118-128.
29. Madorin, W. S., T. Rui, N. Sugimoto, O. Handa, G. Cepinskas, and P. R. Kvietys. 2004. Cardiac myocytes activated by septic plasma promote neutrophil transendothelial migration: role of platelet-activating factor and the chemokines LIX and KC. Circ. Res. 94: 944-951.
30. Cepinskas, G., M. Sandig, and P. R. Kvietys. 1999. PAF-induced elastase-dependent neutrophil transendothelial migration is associated with the mobilization of elastase to the neutrophil surface and localization to the migrating front. J. Cell Sci. 112: 1937-1945.
31. Yoshida, N., D. G. Granger, D. C. Anderson, R. Rothlein, C. Lane, and P. R. Kvietys. 1992. Anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells. Am. J. Physiol. 262: H1891-H1898.
32. Dhanjal, T. S., C. Pendaries, E. A. Ross, M. K. Larson, M. B. Protty, C. D. Buckley, and S. P. Watson. 2007. A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice. Blood 109: 4237-4244.
33. Watanabe, N., K. Ikuta, K. Okazaki, H. Nakase, Y. Tabata, M. Matsuura, H. Tamaki, C. Kawanami, T. Honjo, and T. Chiba. 2003. Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Dig. Dis. Sci. 48: 408-414.
34. Gay, N. J., and M. Gangloff. 2007. Structure and function of Toll receptors and their ligands. Annu. Rev. Biochem. 76: 141-165.
35. Park, J. S., F. Gamboni-Robertson, Q. He, D. Svetkauskaite, J. Y. Kim, D. Strassheim, J. W. Sohn, S. Yamada, I. Maruyama, and A. Banerjee. 2006. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am. J. Physiol. 290: C917-C924.
36. Wu, Y., P. Stabach, M. Michaud, and J. A. Madri. 2005. Neutrophils lacking platelet-endothelial cell adhesion molecule-1 exhibit loss of directionality and motility in CXCR2-mediated chemotaxis. J. Immunol. 175: 3484-3491.
37. Sauer, A., T. Hartung, J. Aigner, and A. Wendel. 1996. Endotoxin-inducible granulocyte-mediated hepatocytotoxicity requires adhesion and serine protease release. J. Leukocyte Biol. 60: 633-643.
38. Wang, S., J. P. Dangerfield, R. E. Young, and S. Nourshargh. 2005. PECAM-1, α6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J. Cell Sci. 118: 2067-2076.
39. Vicente-Manzanares, M., and E. Sanchez-Madrid. 2004. Role of the cytoskeleton during leukocyte responses. Nat. Rev. Immunol. 4: 110-122.
40. Carrithers, M., S. Tandon, S. Canosa, M. Michaud, D. Graesser, and J. A. Madri. 2005. Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am. J. Pathol. 166: 185-196.
41. Maas, M., M. Stapleton, C. Bergom, D. L. Mattson, D. K. Newman, and P. J. Newman. 2005. Endothelial cell PECAM-1 confers protection against endotoxic shock. Am. J. Physiol. 288: H159-H164.
42. Rijcken, E., R. B. Mennigen, S. D. Schaefer, M. G. Laukoetter, C. Anthoni, H. U. Spiegel, M. Bruewer, N. Senninger, and C. F. Krieglstein. 2007. PECAM-1 (CD 31) mediates transendothelial leukocyte migration in experimental colitis. Am. J. Physiol. 293: G446-G452.