Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer

World Journal of Gastroenterology

Volumn 14, Issue 17, 2008, Pages 2702-2714

  Maehata, Tadateru ^a   Taniguchi, Hiroaki ^b   Yamamoto, Hiroyuki ^b   Nosho, Kutsuhiko ^b   Adachi, Yasushi ^b   Miyamoto, Nobuki ^b   Miyamoto, Chie ^b   Akutsu, Noriyuki ^b   Yamaoka, Satoshi ^b   Itoh, Fumio ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Dickkopf genes; Gastrointestinal cancer; Kremen2 gene; Methylation; Wnt signaling

Indexed keywords

DICKKOPF PROTEIN; GENE PRODUCT; HISTONE DEACETYLASE INHIBITOR; KREMEN 2 PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; BETA CATENIN; CTNNB1 PROTEIN, HUMAN; DKK1 PROTEIN, HUMAN; DKK2 PROTEIN, HUMAN; DKK3 PROTEIN, HUMAN; DKK4 PROTEIN, HUMAN; KREMEN2 PROTEIN, HUMAN; MEMBRANE PROTEIN; MESSENGER RNA; SIGNAL PEPTIDE;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CANCER TISSUE; CARCINOGENESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DEMETHYLATION; DIGESTIVE SYSTEM CANCER; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPH NODE METASTASIS; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; TRANSCRIPTION REGULATION; CELL PROLIFERATION; GASTROINTESTINAL TUMOR; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; CPG ISLANDS; DNA METHYLATION; GASTROINTESTINAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NEOPLASM INVASIVENESS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 49649113673     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.2702     Document Type: Article

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