Methylnaltrexone (Relistor) for opioid-induced constipation

Medical Letter on Drugs and Therapeutics

Volumn 50, Issue 1292, 2008, Pages 63-64

  Abramowicz, Mark ^m   Zuccotti, Gianna ^a   Pflomm, Jean Marie ^m   Morey, Susan ^m   Epstein, Eric J ^b   Hansten, Philip D ^c   Hirsch, Jules ^d   Juurlink, David N ^e   Kim, Richard B ^f   Mandell, Gerald L ^g   Meinertz, Hans ^h   Roden, Dan M ⁱ   Simons, F Estelle R ^j   Steigbigel, Neal H ^k   Goodstein, Donna ^m   Faucard, Amy ^m   Covey, Cynthia Macapagal ^m   Schwartz, Lauren K ^l   Brown, Cheryl ^m   Donohue, Liz ^m   Wong, Susie ^m   Carbona, Gene ^m   Romatowski, Cristine ^m   Valentino, Joanne F ^m   Wissner Levy, Yosef ^m   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^f UNIVERSITY OF WESTERN ONTARIO   (Canada)

^g UNIVERSITY OF VIRGINIA   (United States)

^h Mental Health Services CPH   (Denmark)

ⁱ VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF MANITOBA   (Canada)

^k NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^m NONE

more..

Author keywords

[No Author keywords available]

Indexed keywords

17 METHYLNALTREXONE; ALVIMOPAN; MU OPIATE RECEPTOR; OPIATE; PLACEBO; RELISTOR; UNCLASSIFIED DRUG; DRUG DERIVATIVE; NALTREXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST; QUATERNARY AMMONIUM DERIVATIVE;

ABDOMINAL PAIN; ADVANCED CANCER; AREA UNDER THE CURVE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG EXCRETION; DRUG INDUCED DISEASE; DRUG METABOLISM; DRUG RESPONSE; FLATULENCE; HUMAN; NAUSEA; PALLIATIVE THERAPY; RECEPTOR BLOCKING; RECOMMENDED DRUG DOSE; SHORT SURVEY; ARTICLE; CHEMICALLY INDUCED DISORDER; DRUG INTERACTION; METABOLISM; RANDOMIZED CONTROLLED TRIAL; TERMINAL CARE;

ANALGESICS, OPIOID; CONSTIPATION; DRUG INTERACTIONS; HUMANS; NALTREXONE; NARCOTIC ANTAGONISTS; QUATERNARY AMMONIUM COMPOUNDS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TERMINAL CARE;

EID: 49649094719     PISSN: 0025732X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (4)

1. L Shaiova et al. A review of methylnaltrexone, a peripheral opioid receptor antagonist, and its role in opioid-induced constipation. Palliat Support Care 2007; 5:161.
2. J Thomas et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med 2008; 358:2332.
3. Clinical review: methylnaltrexone bromide. Food and Drug Administration web site. Available at http://www.fda.gov/cder/foi/nda/2008/021964s000-medr-p1. pdf. Accessed August 4, 2008.
4. Price according to the most recent data (June 30, 2008) from retail pharmacies nationwide according to Wolters Kluwer Health.