Influence of tissue optical properties on laser Doppler perfusion imaging, accounting for photon penetration depth and the laser speckle phenomenon

Journal of Biomedical Optics

Volumn 13, Issue 2, 2008, Pages

  Rajan, Vinayakrishnan ^a   Varghese, Babu ^a   Van Leeuwen, Ton G ^a   Steenbergen, Wiendelt ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

coherence area; depth sensitivity; laser Doppler perfusion imaging; Monte Carlo simulations; sampling depth; tissue optical properties

Indexed keywords

ABSORPTION LEVELS; BEAM DIAMETERS; DEPTH SENSITIVITY; IN-VIVO; LASER DOPPLER PERFUSION IMAGING; LASER SPECKLE; LOW CONCENTRATIONS; MONTE CARLO SIMULATION; MOVING PARTICLES; NORMAL SKIN; PHOTON PENETRATION; PHOTON STATISTICS; PORT WINE STAINS; SCATTERING LEVELS; SIGNAL RESPONSE; SPECKLE SIZE; TISSUE OPTICAL PROPERTIES; TURBID MEDIUM;

CLASSIFIERS; COMPUTER SIMULATION; DOPPLER EFFECT; LASER DOPPLER VELOCIMETERS; MONTE CARLO METHODS; PHOTONS; SPECKLE; TISSUE; WINE;

OPTICAL PROPERTIES;

ARTICLE; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; BLOOD VESSEL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; IMAGE ENHANCEMENT; LASER DOPPLER FLOWMETRY; METHODOLOGY; PHOTOMETRY; PHOTON; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

BLOOD FLOW VELOCITY; BLOOD VESSELS; COMPUTER SIMULATION; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LASER-DOPPLER FLOWMETRY; MODELS, CARDIOVASCULAR; NEPHELOMETRY AND TURBIDIMETRY; PHOTONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 49649091827     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2904958     Document Type: Article

References (17)

1. H., Fujii, K., Nohira, Y., Yamamoto, H., Ikawa, and T., Ohura, " Evaluation of blood flow by laser speckle image sensing: part 1, ", Appl. Opt., 26, 5321-5325 (1987). apo APOPAI 0003-6935
2. J. D., Briers and S., Webster, " Quasi-real time digital version of single-exposure speckle photography for full-field monitoring of velocity or flow fields, ", Opt. Commun., 116, 36-42 (1995). opc OPCOB8 0030-4018 10.1016/0030-4018(95)00042-7
3. T. J. H., Essex and P. O., Byrne, " A laser Doppler scanner for imaging blood flow in skin, ", J. Biomed. Eng., 13, 189-194 (1991). jie JBIEDR 0141-5425 10.1016/0141-5425(91)90125-Q
4. K., Wårdell, A., Jakobsson, and G. E., Nilsson, " Laser Doppler perfusion imaging by dynamic light scattering, ", IEEE Trans. Biomed. Eng., 40, 309-316 (1993). ieb IEBEAX 0018-9294 10.1109/10.222322
5. D. A., Boas, L. E., Campbell, and A. G., Yodh, " Scattering and imaging with diffusing temporal field correlations, ", Phys. Rev. Lett., 75, 1855-1858 (1995). prl PRLTAO 0031-9007 10.1103/PhysRevLett.75.1855
6. J. D., Briers, " Laser Doppler and time-varying speckle: a conciliation, ", J. Opt. Soc. Am. A, 13, 345-350 (1996). joa JOAOD6 0740-3232
7. V., Rajan, B., Varghese, T. G., van Leeuwen, and W., Steenbergen, " Speckles in laser Doppler perfusion imaging, ", Opt. Lett., 31, 468-470 (2006). opl OPLEDP 0146-9592 10.1364/OL.31.000468
8. A., Fullerton, B., Rode, and J., Serup, " Skin irritation typing and grading based on laser Doppler perfusion imaging, ", Skin Res. Technol., 8, 23-31 (2002). b5r ZZZZZZ 0909-752X
9. E. J., Droog, W., Steenbergen, and F., Sjöberg, " Measurement of depth of burns by laser Doppler perfusion Imaging, ", Burns, 27, 561-568 (2001). 33s ZZZZZZ 0305-4179
10. V., Rajan, B., Varghese, T. G., van Leeuwen, and W., Steenbergen, " Quantification of spatial intensity correlations and photodetector intensity fluctuations of coherent light reflected from turbid particle suspensions, ", Phys. Rev. E, 75, 060901-4 (2007). pre PLEEE8 1063-651X 10.1103/PhysRevE.75.060901
11. R., Bonner and R., Nossal, " Model for laser Doppler measurements of blood flow in tissue, ", Appl. Opt., 20, 2097-2107 (1981). apo APOPAI 0003-6935
12. F. F. M., de Mul, M. H., Koelink, M. L., Kok, P. J., Harmsma, J., Greve, R., Graaff, and J. G., Aarnoudse, " Laser Doppler velocimetry and Monte Carlo simulations on models for blood perfusion in tissue, ", Appl. Opt., 34, 6595-6611 (1995). apo APOPAI 0003-6935
13. R. G. M., Kolkman, E., Hondebrink, W., Steenbergen, T. G., van Leeuwen, and F. F. M., de Mul, " Photoacoustic imaging of blood vessels with a double ring sensor featuring a narrow angular aperture, ", J. Biomed. Opt., 9, 1327-1335 (2004). jbo JBOPFO 1083-3668 10.1117/1.1805556
14. L. O., Svaasand, L. T., Norvang, E. J., Fiskerstrand, E. K. S., Stopps, M. W., Berns and J. S., Nelson, " Tissue parameters determining the visual appearance of normal skin and port-wine stains, ", Lasers Med. Sci., 10, 55-65 (1995). cfo ZZZZZZ 0268-8921
15. M. G. D., Karlsson and K., Wårdell, " Polarized laser Doppler perfusion imaging - reduction of movement-induced artifacts, ", J. Biomed. Opt., 10, 064002 (2005). jbo JBOPFO 1083-3668 10.1117/1.2120467
16. B., Varghese, V., Rajan, T. G., van Leeuwen, and W., Steenbergen, " Path-length-resolved measurements of multiple scattered photons in static and dynamic turbid media using phase-modulated low-coherence interferometry, ", J. Biomed. Opt., 12, 024020-7 (2007). jbo JBOPFO 1083-3668 10.1117/1.2714795
17. V., Rajan, B., Varghese, T. G., van Leeuwen, and W., Steenbergen, " Effect of speckles on the depth sensitivity of laser Doppler perfusion imaging, ", Opt. Express, 15, 10911-10919 (2007). 8mi OPEXFF 1094-4087 10.1364/OE.15.010911