Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons

Osteoporosis International

Volumn 19, Issue 9, 2008, Pages 1315-1322

  Ott, S M ^a   LaCroix, A Z ^b   Scholes, D ^b   Ichikawa, L E ^b   Wu, K ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b CENTER FOR HEALTH STUDIES   (United States)

Author keywords

Bicarbonate; Clinical trial; Hypercalciuria; Thiazides

Indexed keywords

BICARBONATE; CALCIUM; HYDROCHLOROTHIAZIDE; MAGNESIUM; PARATHYROID HORMONE; PHOSPHATE; PLACEBO; SODIUM;

ADULT; AGED; ARTICLE; CALCIUM METABOLISM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; FRACTURE; GERIATRIC CARE; HUMAN; LOW DRUG DOSE; MALE; MINERAL BLOOD LEVEL; MINERAL METABOLISM; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; URINALYSIS;

AGED; BICARBONATES; BONE AND BONES; BONE DENSITY; BONE RESORPTION; CALCIUM; CALCIUM, DIETARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; HYDROCHLOROTHIAZIDE; MALE; MIDDLE AGED; MINERALS; SEX FACTORS;

EID: 49549119171     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-008-0612-4     Document Type: Article

References (27)

1. AZ LaCroix J Wienpahl LR White RB Wallace PA Scherr LK George J Cornoni-Huntley AM Ostfeld 1990 Thiazide diuretic agents and the incidence of hip fracture N Engl J Med 322 286 290
2. G Jones T Nguyen PN Sambrook JA Eisman 1995 Thiazide diuretics and fractures: can meta-analysis help? J Bone Miner Res 10 106 111
3. D Feskanich WC Willett MJ Stampfer GA Colditz 1997 A prospective study of thiazide use and fractures in women Osteoporos Int 7 79 84
4. RG Schlienger ME Kraenzlin SS Jick CR Meier 2004 Use of beta-blockers and risk of fractures Jama 292 1326 1332
5. L Rejnmark P Vestergaard L Mosekilde 2005 Reduced fracture risk in users of thiazide diuretics Calcif Tissue Int 76 167 175
6. M Wiens M Etminan SS Gill B Takkouche 2006 Effects of antihypertensive drug treatments on fracture outcomes: a meta-analysis of observational studies J Intern Med 260 350 362
7. DC Bauer WS Browner JA Cauley ES Orwoll JC Scott DM Black JL Tao SR Cummings 1993 Factors associated with appendicular bone mass in older women. The Study of Osteoporotic Fractures Research Group Ann Intern Med 118 657 665
8. ES Orwoll L Bevan KR Phipps 2000 Determinants of bone mineral density in older men Osteoporos Int 11 815 821
9. I Transbol MS Christensen GF Jensen C Christiansen P McNair 1982 Thiazide for the postponement of postmenopausal bone loss Metabolism 31 383 386
10. AZ LaCroix SM Ott L Ichikawa D Scholes WE Barlow 2000 Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults. A randomized, double-blind, placebo-controlled trial Ann Intern Med 133 516 526
11. IR Reid RW Ames BJ Orr-Walker JM Clearwater AM Horne MC Evans MA Murray AR McNeil GD Gamble 2000 Hydrochlorothiazide reduces loss of cortical bone in normal postmenopausal women: a randomized controlled trial Am J Med 109 362 370
12. RD Wasnich JW Davis YF He H Petrovich PD Ross 1995 A randomized, double-masked, placebo-controlled trial of chlorthalidone and bone loss in elderly women Osteoporos Int 5 247 251
13. AC Looker HW Wahner WL Dunn MS Calvo TB Harris SP Heyse CC Johnston Jr R Lindsay 1998 Updated data on proximal femur bone mineral levels of US adults Osteoporos Int 8 468 489
14. A Kristal Z Feng R Coates A Oberman V George 1997 Associations of race/ethnicity, education, and dietary intervention with the validity and reliability of a food frequency questionnaire: the Women's Health Trial Feasibility Study in Minority Populations Am j Epidemiol 146 856 869
15. GM Preminger CY Pak 1987 Eventual attenuation of hypocalciuric response to hydrochlorothiazide in absorptive hypercalciuria J Urol 137 1104 1109
16. CV Odvina GM Preminger JS Lindberg OW Moe CY Pak 2003 Long-term combined treatment with thiazide and potassium citrate in nephrolithiasis does not lead to hypokalemia or hypochloremic metabolic alkalosis Kidney Int 63 240 247
17. A Greenberg 2000 Diuretic complications Am J Med Sci 319 10 24
18. EL Barry FA Gesek MR Kaplan SC Hebert PA Friedman 1997 Expression of the sodium-chloride cotransporter in osteoblast-like cells: effect of thiazide diuretics Am J Physiol 272 C109 116
19. A Lalande C Roux AM Graulet P Schiavi MC De Vernejoul 1998 The diuretic indapamide increases bone mass and decreases bone resorption in spontaneously hypertensive rats supplemented with sodium J Bone Miner Res 13 1444 1450
20. L Nicolet-Barousse A Blanchard C Roux L Pietri M Bloch-Faure S Kolta C Chappard V Geoffroy C Morieux X Jeunemaitre GE Shull P Meneton M Paillard P Houillier MC De Vernejoul 2005 Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice J Bone Miner Res 20 799 808
21. H Mayan I Vered M Mouallem M Tzadok-Witkon R Pauzner Z Farfel 2002 Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density J Clin Endocrinol Metab 87 3248 3254
22. RA Sutton 1985 Diuretics and calcium metabolism Am J Kidney Dis 5 4 9
23. MJ Bollard RW Ames AM Horne BJ Orr-Walker GD Gamble IR Reed 2007 The effect of treatment with a thiazide diuretic for 4 years on bone density in normal postmenopausal women Osteoporos Int 18 479 486
24. J Lemann Jr DA Bushinsky LL Hamm 2003 Bone buffering of acid and base in humans Am J Physiol Renal Physiol 285 F811 832
25. DA Bushinsky 2001 Acid-base imbalance and the skeleton Eur J Nutr 40 238 244
26. LA Frassetto E Nash RC Morris A Sebastian 2000 Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion Kidney Int 58 748 752
27. S Jehle A Zanetti J Muser HN Hulter R Krapf 2006 Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia J Am Soc Nephrol 17 3213 3222