Influence of stirrer type on mixture homogeneity in continuous powder mixing: A model case and a pharmaceutical case

Chemical Engineering Research and Design

Volumn 86, Issue 9, 2008, Pages 1027-1037

  Marikh, K ^a   Berthiaux, H ^a   Gatumel, C ^a   Mizonov, V ^b   Barantseva, E ^b  

^a ECOLE DES MINES D ALBI CARMAUX   (France)

^b IVANOVO STATE POWER ENGINEERING UNIVERSITY   (Russian Federation)

Author keywords

Continuous mixing; Mixture homogeneity; Particulate solids; Pharmaceutical mixtures; Stirrer design

Indexed keywords

BATCH DATA PROCESSING; FLUIDIZATION; MIXERS (MACHINERY); MIXING; POWDERS;

BATCH PROCESSING; CONTINUOUS MIXING; CONTINUOUS POWDER MIXING; DENSE PHASE; FRAME TYPE; HOLD-UP; MIXER DESIGN; MIXTURE HOMOGENEITY; OPERATING CONDITIONS; PARTICULATE SOLIDS; PHARMACEUTICAL MIXTURES; PILOT-SCALE; POWDER FLOWS; ROTATIONAL SPEEDS; SCIENTIFIC LITERATURE; STIRRER DESIGN; TWO TYPES;

MIXTURES;

EID: 49549112941     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cherd.2008.04.001     Document Type: Article

References (13)

1. Berthiaux, H., Marikh, K., Gatumel, C. Gautier, R., 2006, Continuous mixing of pharmaceutical powder mixtures, in: Proceedings of the 5th World Congress on Particle Technology, AIChE spring Meeting, CD-ROM edition, Orlando.
2. Coulson J.M., Richardson J.F., and Sinott R.K. Chemical Engineering-Design vol. 6 (1983), Pergamon Press
3. Danckwerts P.V. Theory of mixtures and mixing. Research 6 (1953) 355-361
4. Hausner H.H. Problems of powder mixing and blending. Particulate Matter 11 (1972) 3-11
5. Kehlenbeck, V., Sommer, K., 2003, Possibilities to Smooth the Mass Flow Pulsations of Volumetric Feeders, CHOPS'4, Budapest, pp. 14.13-14.19.
6. Knutsen G.F., and Landmo G.I. Mixing of powders. The Postec Newsletter 15 (1996) 27-30
7. Laurent B.F.C., and Bridgwater J. Influence of agitator on powder flow. Chemical Engineering Science 57 (2002) 3781-3793
8. Marikh, K., 2003, Mélange en continu des solides divisés: dynamique et modélisation, PhD Thesis, INPL Nancy, France.
9. Marikh K., Berthiaux H., Mizonov V., and Barantseva E. Experimental study of the stirring conditions taking place in a pilot plant continuous mixer of particulate solids. Powder Technology 157 (2005) 138-143
10. Marikh K., Berthiaux H., Mizonov V., Barntseva E., and Ponomarev D. Flow analysis and Markov chain modelling to quantify the agitation effect in continuous powder mixer. Chemical Engineering Research and Design 84 A11 (2006) 1059-1074
11. Muerza S., Berthiaux H., Massol-Chaudeur S., and Thomas G. A dynamic study of static mixing using on-line image analysis. Powder Technology 128 (2002) 195-204
12. Pernenkil L., and Cooney C.L. A review on the continuous blending of powders. Chemical Engineering Science 61 (2006) 720-742
13. Sudah O., Chester A.W., Kowalski J.A., Beeckman J.W., and Muzzio F.J. Quantitative characterization of mixing processes in rotary calciners. Powder Technology 126 (2002) 166-173