Benefits and risks of intranigral transplantation of GABA-producing cells subsequent to the establishment of kindling-induced seizures

Neurobiology of Disease

Volumn 31, Issue 3, 2008, Pages 342-354

  Nolte, Marc W ^c   Löscher, Wolfgang ^a,b   Herden, Christiane ^a   Freed, William J ^d   Gernert, Manuela ^a,b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

^c ABBOTT GMBH AND CO KG   (Germany)

^d NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Basal ganglia; Gene therapy; Genetically engineered cells; Grafting; Kindling; Neural transplantation; Seizures; Substantia nigra pars reticulata

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; COMPLEMENTARY DNA; GLUTAMATE DECARBOXYLASE;

ALLOTRANSPLANTATION; AMYGDALOID NUCLEUS; ANIMAL CELL; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN TRANSPLANTATION; CELL IMMORTALIZATION; CELL INFILTRATION; CELL LINE; CONTROLLED STUDY; FEMALE; GENETIC ENGINEERING; GENETIC TRANSFECTION; GLIOSIS; GRAFT REJECTION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INFLAMMATORY CELL; KINDLING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RISK ASSESSMENT; SEIZURE; SUBSTANTIA NIGRA; TEMPORAL LOBE EPILEPSY; TISSUE REACTION;

ANIMALS; BRAIN TISSUE TRANSPLANTATION; CELL LINE, TRANSFORMED; DISEASE MODELS, ANIMAL; EPILEPSY; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENE THERAPY; GLUTAMATE DECARBOXYLASE; GRAFT REJECTION; HUMANS; KINDLING, NEUROLOGIC; MICROGLIA; NEURAL INHIBITION; NEURONS; RATS; RATS, WISTAR; RISK ASSESSMENT; STEM CELL TRANSPLANTATION; SUBSTANTIA NIGRA; TRANSFECTION; TREATMENT OUTCOME; UP-REGULATION;

EID: 49549091329     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.05.010     Document Type: Article

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