메뉴 건너뛰기




Volumn 5, Issue 3, 2008, Pages 235-241

New therapeutic agents in the management of HIV: An overview of darunavir for clinicians

Author keywords

Drug resistance; HAART; Prezista; Protease inhibitor

Indexed keywords

ABACAVIR; ATAZANAVIR; ATORVASTATIN; CLARITHROMYCIN; DARUNAVIR; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; ETRAVIRINE; INDINAVIR; LAMIVUDINE; LOPINAVIR; METHADONE; NEVIRAPINE; OMEPRAZOLE; PRAVASTATIN; PROTEINASE INHIBITOR; RALTEGRAVIR; RANITIDINE; RIFABUTIN; RITONAVIR; SAQUINAVIR; STAVUDINE; TENOFOVIR; TIPRANAVIR; UNINDEXED DRUG; VIRUS RNA; WARFARIN; ZIDOVUDINE;

EID: 49449119140     PISSN: 14485028     EISSN: None     Source Type: Journal    
DOI: 10.1071/SH08005     Document Type: Review
Times cited : (4)

References (24)
  • 1
    • 34547421880 scopus 로고    scopus 로고
    • Darunavir: A second-generation protease inhibitor
    • doi: 10.2146/ajhp060668
    • Busse KHS, Penzak SR. Darunavir: a second-generation protease inhibitor. Am J Health Syst Pharm 2007; 64: 1593-602. doi: 10.2146/ajhp060668
    • (2007) Am J Health Syst Pharm , vol.64 , pp. 1593-1602
    • Busse, K.H.S.1    Penzak, S.R.2
  • 2
    • 33847041109 scopus 로고    scopus 로고
    • Efficacy and safety of TMC114/ritonavir in treatment-experienced HIV patients: 24-week results of POWER 1
    • doi: 10.1097/QAD.0b013e328013d9d7
    • Katlama C, Esposito R, Gatell JM, Goffard J-C, Grinsztejn B, Pozniak A, et al. Efficacy and safety of TMC114/ritonavir in treatment-experienced HIV patients: 24-week results of POWER 1. AIDS 2007; 21: 395-402. doi: 10.1097/QAD.0b013e328013d9d7
    • (2007) AIDS , vol.21 , pp. 395-402
    • Katlama, C.1    Esposito, R.2    Gatell, J.M.3    Goffard, J.-C.4    Grinsztejn, B.5    Pozniak, A.6
  • 3
    • 34047205841 scopus 로고    scopus 로고
    • Week 24 efficacy and safety of TMC114/ritonavir in treatment-experienced HIV patients
    • doi: 10.1097/QAD.0b013e3280b07b47
    • Haubrich R, Berger D, Chiliade P, Colson A, Conant M, Gallant J, et al. Week 24 efficacy and safety of TMC114/ritonavir in treatment-experienced HIV patients. AIDS 2007; 21: F11-8. doi: 10.1097/QAD.0b013e3280b07b47
    • (2007) AIDS , vol.21
    • Haubrich, R.1    Berger, D.2    Chiliade, P.3    Colson, A.4    Conant, M.5    Gallant, J.6
  • 5
    • 34047207229 scopus 로고    scopus 로고
    • Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: A pooled subgroup analysis of data from two randomised trials
    • doi: 10.1016/S0140-6736(07)60497-8
    • Clotet B, Bellos N, Molina J-M, Cooper D, Goffard J-C, Lazzarin A, et al. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. Lancet 2007; 369: 1169-78. doi: 10.1016/S0140-6736(07)60497-8
    • (2007) Lancet , vol.369 , pp. 1169-1178
    • Clotet, B.1    Bellos, N.2    Molina, J.-M.3    Cooper, D.4    Goffard, J.-C.5    Lazzarin, A.6
  • 6
    • 34347329093 scopus 로고    scopus 로고
    • Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: A randomised controlled phase III trial
    • doi: 10.1016/S0140-6736(07)61049-6
    • Madruga JV, Berger D, McMurchie M, Suter F, Banhegyi D, Ruxrungtham K, et al. Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomised controlled phase III trial. Lancet 2007; 370: 49-58. doi: 10.1016/S0140-6736(07)61049-6
    • (2007) Lancet , vol.370 , pp. 49-58
    • Madruga, J.V.1    Berger, D.2    McMurchie, M.3    Suter, F.4    Banhegyi, D.5    Ruxrungtham, K.6
  • 8
    • 34347354196 scopus 로고    scopus 로고
    • Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial
    • doi: 10.1016/S0140-6736(07)61048-4
    • Lazzarin A, Campbell T, Clotet B, Johnson M, Katlama C, Moll A, et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370: 39-48. doi: 10.1016/S0140-6736(07)61048-4
    • (2007) Lancet , vol.370 , pp. 39-48
    • Lazzarin, A.1    Campbell, T.2    Clotet, B.3    Johnson, M.4    Katlama, C.5    Moll, A.6
  • 9
    • 34347327010 scopus 로고    scopus 로고
    • Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial
    • doi: 10.1016/S0140-6736(07)61047-2
    • Madruga JV, Cahn P, Grinsztejn B, Haubrich R, Lalezari J, Mills A, et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370: 29-38. doi: 10.1016/S0140-6736(07)61047-2
    • (2007) Lancet , vol.370 , pp. 29-38
    • Madruga, J.V.1    Cahn, P.2    Grinsztejn, B.3    Haubrich, R.4    Lalezari, J.5    Mills, A.6
  • 10
    • 19544386471 scopus 로고    scopus 로고
    • TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
    • doi: 10.1128/AAC.49.6.2314-2321.2005
    • De Meyer S, Azijn H, Surleraux D, Jochmans D, Tahri A, Pauwels R, et al. TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates. Antimicrob Agents Chemother 2005; 49: 2314-21. doi: 10.1128/AAC.49.6.2314-2321.2005
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2314-2321
    • De Meyer, S.1    Azijn, H.2    Surleraux, D.3    Jochmans, D.4    Tahri, A.5    Pauwels, R.6
  • 11
    • 49449100679 scopus 로고    scopus 로고
    • Collier ACGJ, Katner HP, Rozembaum W, Vangeneugden T, Lefebvre E. Safety and efficacy of TMC114/r (darunavir/ritonavir) by gender, age and race: combined 24-week analysis of POWER 1, 2 and 3. Program and abstract of the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy 2006; San Francisco, California, USA. Abstract H-1396.
    • Collier ACGJ, Katner HP, Rozembaum W, Vangeneugden T, Lefebvre E. Safety and efficacy of TMC114/r (darunavir/ritonavir) by gender, age and race: combined 24-week analysis of POWER 1, 2 and 3. Program and abstract of the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy 2006; San Francisco, California, USA. Abstract H-1396.
  • 13
    • 33947520634 scopus 로고    scopus 로고
    • The effect of different meal types on the pharmacokinetics of darunavir (TMC114)/ritonavir in HIV-negative healthy volunteers
    • doi: 10.1177/0091270006298603
    • Sekar V, Kestens D, Spinosa-Guzman S, De Pauw M, De Paepe E, Vangeneugden T, et al. The effect of different meal types on the pharmacokinetics of darunavir (TMC114)/ritonavir in HIV-negative healthy volunteers. J Clin Pharmacol 2007; 47: 479-84. doi: 10.1177/0091270006298603
    • (2007) J Clin Pharmacol , vol.47 , pp. 479-484
    • Sekar, V.1    Kestens, D.2    Spinosa-Guzman, S.3    De Pauw, M.4    De Paepe, E.5    Vangeneugden, T.6
  • 14
    • 34347393141 scopus 로고    scopus 로고
    • Pharmacokinetics of darunavir (TMC114) and atazanavir during coadministration in HIV-negative, healthy volunteers
    • doi: 10.2165/00126839-200708040-00004
    • Sekar VJ, Lefebvre E, De Marez T, Spinosa-Guzman S, De Pauw M, De Paepe E, et al. Pharmacokinetics of darunavir (TMC114) and atazanavir during coadministration in HIV-negative, healthy volunteers. Drugs R D 2007; 8: 241-8. doi: 10.2165/00126839-200708040-00004
    • (2007) Drugs R D , vol.8 , pp. 241-248
    • Sekar, V.J.1    Lefebvre, E.2    De Marez, T.3    Spinosa-Guzman, S.4    De Pauw, M.5    De Paepe, E.6
  • 15
    • 34547780413 scopus 로고    scopus 로고
    • Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers
    • Scholler-Gyure M, Kakuda TN, Sekar V, Woodfall B, De Smedt G, Lefebvre E, et al. Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers. Antivir Ther 2007; 12: 789-96.
    • (2007) Antivir Ther , vol.12 , pp. 789-796
    • Scholler-Gyure, M.1    Kakuda, T.N.2    Sekar, V.3    Woodfall, B.4    De Smedt, G.5    Lefebvre, E.6
  • 18
    • 35348879698 scopus 로고    scopus 로고
    • Defining HIV susceptibility to new antiretroviral agents-darunavir
    • doi: 10.1086/521631
    • Haubrich R. Defining HIV susceptibility to new antiretroviral agents-darunavir. J Infect Dis 2007; 196: 1125-7. doi: 10.1086/521631
    • (2007) J Infect Dis , vol.196 , pp. 1125-1127
    • Haubrich, R.1
  • 19
    • 35348860148 scopus 로고    scopus 로고
    • Prevalence of darunavir resistance-associated mutations: Patterns of occurrence and association with past treatment
    • doi: 10.1086/521624
    • Mitsuya Y, Liu TF, Rhee S-Y, Fessel WJ, Shafer RW. Prevalence of darunavir resistance-associated mutations: patterns of occurrence and association with past treatment. J Infect Dis 2007; 196: 1177-9. doi: 10.1086/521624
    • (2007) J Infect Dis , vol.196 , pp. 1177-1179
    • Mitsuya, Y.1    Liu, T.F.2    Rhee, S.-Y.3    Fessel, W.J.4    Shafer, R.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.