A reassessment of the in vitro RBC haemolysis assay with defibrinated sheep blood for the determination of the ocular irritation potential of cosmetic products: Comparison with the in vivo Draize rabbit test

ATLA Alternatives to Laboratory Animals

Volumn 36, Issue 3, 2008, Pages 275-284

  Nunes Alves, Eloísa ^a   De Farias Presgrave, Rosaura ^a   França Presgrave, Octavio Auguste ^a   Peres Sabagh, Fernanda ^a   Rolim De Freitas, João Carlos Borges ^a   Pinto Corrado, Alexandre ^a,b  

^a Oswaldo Cruz Foundation   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Draize test; Eye irritation; Haemolysis; Protein denaturation; RBC assay

Indexed keywords

COSMETIC; SHAMPOO;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRAIZE TEST; ERYTHROCYTE; ERYTHROCYTE HEMOLYSIS ASSAY; EYE IRRITATION; FEMALE; INTERMETHOD COMPARISON; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; RABBIT; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SHEEP; STATISTICAL SIGNIFICANCE; VALIDATION STUDY;

ORYCTOLAGUS CUNICULUS; OVIS ARIES;

EID: 49449116536     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290803600305     Document Type: Article

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