-
1
-
-
0023024730
-
Purification and characterization of Clostridium perfringens iota toxin: Dependence on two nonlinked proteins for biological activity
-
Stiles, B. G., and Wilkens, T. D. (1986) Purification and characterization of Clostridium perfringens iota toxin: dependence on two nonlinked proteins for biological activity. Infect. Immun. 54, 683-688.
-
(1986)
Infect. Immun
, vol.54
, pp. 683-688
-
-
Stiles, B.G.1
Wilkens, T.D.2
-
2
-
-
0024339751
-
Purification of the Clostridium spiroforme binary toxin and activity of the toxin on HEp2 cells
-
Popoff, M. R., Milward, F. W., Bancillon, B., and Boquet, P. (1989) Purification of the Clostridium spiroforme binary toxin and activity of the toxin on HEp2 cells. Infect. Immun. 57, 2462-2469.
-
(1989)
Infect. Immun
, vol.57
, pp. 2462-2469
-
-
Popoff, M.R.1
Milward, F.W.2
Bancillon, B.3
Boquet, P.4
-
3
-
-
0031004306
-
Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196
-
Perelle, S., Gibert, M., bourlioux, P., Corthier, G., and Popoff, M. R. (1997) Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196. Infect. Immun. 65, 1402-1407.
-
(1997)
Infect. Immun
, vol.65
, pp. 1402-1407
-
-
Perelle, S.1
Gibert, M.2
bourlioux, P.3
Corthier, G.4
Popoff, M.R.5
-
4
-
-
0034819726
-
Characterization of the enzymatic component of the ADP-ribosyltransferase toxin CDTa from Clostridium difficile
-
Gülke, I., Pfeifer, G., Liese, J., Fritz, M., Hofmann, F., Aktories, K., and Barth, H. (2001) Characterization of the enzymatic component of the ADP-ribosyltransferase toxin CDTa from Clostridium difficile. Infect. Immun. 69, 6004-6011.
-
(2001)
Infect. Immun
, vol.69
, pp. 6004-6011
-
-
Gülke, I.1
Pfeifer, G.2
Liese, J.3
Fritz, M.4
Hofmann, F.5
Aktories, K.6
Barth, H.7
-
5
-
-
0032876380
-
Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex
-
Han, S., Craig, J. A., Putnam, C. D., Carozzi, N. B., and Tainer, J. A. (1999) Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex. Nat. Struct. Biol. 6, 932-936.
-
(1999)
Nat. Struct. Biol
, vol.6
, pp. 932-936
-
-
Han, S.1
Craig, J.A.2
Putnam, C.D.3
Carozzi, N.B.4
Tainer, J.A.5
-
6
-
-
4544264417
-
Binary bacterial toxins: Biochemistry, biology, and applications of common Clostridium and Bacillus proteins
-
table
-
Barth, H., Aktories, K., Popoff, M. R., and Stiles, B. G. (2004) Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. Microbiol. Mol. Biol. Rev. 68, 373-402, table.
-
(2004)
Microbiol. Mol. Biol. Rev
, vol.68
, pp. 373-402
-
-
Barth, H.1
Aktories, K.2
Popoff, M.R.3
Stiles, B.G.4
-
7
-
-
0019158135
-
Purification and characterization of two components of botulinum C2 toxin
-
Ohishi, I., Iwasaki, M., and Sakaguchi, G. (1980) Purification and characterization of two components of botulinum C2 toxin. Infect. Immun. 30, 668-673.
-
(1980)
Infect. Immun
, vol.30
, pp. 668-673
-
-
Ohishi, I.1
Iwasaki, M.2
Sakaguchi, G.3
-
8
-
-
0039003839
-
Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification
-
Barth, H., Blöcker, D., Behlke, J., Bergsma-Schutter, W., Brisson, A., Benz, R., and Aktories, K. (2000) Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification. J. Biol. Chem. 275, 18704-18711.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18704-18711
-
-
Barth, H.1
Blöcker, D.2
Behlke, J.3
Bergsma-Schutter, W.4
Brisson, A.5
Benz, R.6
Aktories, K.7
-
9
-
-
0034723205
-
Binding of Clostridium botulinum C2 toxin to asparagine-linked complex and hybrid carbohydrates
-
Eckhardt, M., Barth, H., Blöcker, D., and Aktories, K. (2000) Binding of Clostridium botulinum C2 toxin to asparagine-linked complex and hybrid carbohydrates. J. Biol. Chem. 275, 2328-2334.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 2328-2334
-
-
Eckhardt, M.1
Barth, H.2
Blöcker, D.3
Aktories, K.4
-
10
-
-
0024846136
-
The binary toxin produced by Clostridium botulinum enters cells by receptor-mediated endocytosis to exert its pharmacologic effects
-
Simpson, L. L. (1989) The binary toxin produced by Clostridium botulinum enters cells by receptor-mediated endocytosis to exert its pharmacologic effects. J. Pharmacol. Exp. Ther. 251, 1223-1228.
-
(1989)
J. Pharmacol. Exp. Ther
, vol.251
, pp. 1223-1228
-
-
Simpson, L.L.1
-
11
-
-
0022641097
-
Botulinum C2 toxin ADP-ribosylates actin
-
Aktories, K., Bärmann, M., Ohishi, I., Tsuyama, S., Jakobs, K. H., and Habermann, E. (1986) Botulinum C2 toxin ADP-ribosylates actin. Nature 322, 390-392.
-
(1986)
Nature
, vol.322
, pp. 390-392
-
-
Aktories, K.1
Bärmann, M.2
Ohishi, I.3
Tsuyama, S.4
Jakobs, K.H.5
Habermann, E.6
-
12
-
-
0023708116
-
ADP-ribosylated actin caps the barbed ends of actin filaments
-
Wegner, A., and Aktories, K. (1988) ADP-ribosylated actin caps the barbed ends of actin filaments. J. Biol. Chem. 263, 13739-13742.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 13739-13742
-
-
Wegner, A.1
Aktories, K.2
-
13
-
-
0001128658
-
Anthrax toxins
-
Moss, J, Iglewski, B, Vaughan, M, and Tu, A. T, Eds, pp, Marcel Dekker, New York
-
Leppla, S. H. (1995) Anthrax toxins, in Bacterial toxins and virulence factors in disease (Moss, J., Iglewski, B., Vaughan, M., and Tu, A. T., Eds.) pp 543-572, Marcel Dekker, New York.
-
(1995)
Bacterial toxins and virulence factors in disease
, pp. 543-572
-
-
Leppla, S.H.1
-
14
-
-
0036603521
-
2001: A year of major advances in anthrax toxin research
-
Mourez, M., Lacy, D. B., Cunningham, K., Legmann, R., Sellman, B. R., Mogridge, J., and Collier, R. J. (2002) 2001: a year of major advances in anthrax toxin research. Trends Microbiol. 10, 287-293.
-
(2002)
Trends Microbiol. 10
, pp. 287-293
-
-
Mourez, M.1
Lacy, D.B.2
Cunningham, K.3
Legmann, R.4
Sellman, B.R.5
Mogridge, J.6
Collier, R.J.7
-
15
-
-
34447291354
-
-
Rev. Biochem
-
Young, J. A. and Collier, R. J. (2007) Anthrax toxin: receptor-binding, internalization, pore formation, and translocation, Annu. Rev. Biochem.
-
(2007)
Anthrax toxin: Receptor-binding, internalization, pore formation, and translocation, Annu
-
-
Young, J.A.1
Collier, R.J.2
-
16
-
-
0028018856
-
Anthrax protective antigen forms oligomers during intoxication of mammalian cells
-
Milne, J. C., Furlong, D., Hanna, P. C., Wall, J. S., and Collier, R. J. (1994) Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J. Biol. Chem. 269, 20607-20612.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 20607-20612
-
-
Milne, J.C.1
Furlong, D.2
Hanna, P.C.3
Wall, J.S.4
Collier, R.J.5
-
17
-
-
0031052342
-
Crystal structure of the anthrax toxin protective antigen
-
Petosa, C., Collier, R. J., Klimpel, K. R., Leppla, S. H., and Liddingtom, R. C. (1997) Crystal structure of the anthrax toxin protective antigen. Nature 385, 833-838.
-
(1997)
Nature
, vol.385
, pp. 833-838
-
-
Petosa, C.1
Collier, R.J.2
Klimpel, K.R.3
Leppla, S.H.4
Liddingtom, R.C.5
-
18
-
-
0038208865
-
The C-terminus of component C2II of Clostridium botulinum C2 toxin is essential for receptor binding
-
Blöcker, D., Barth, H., Maier, E., Benz, R., Barbieri, J. T., and Aktories, K. (2000) The C-terminus of component C2II of Clostridium botulinum C2 toxin is essential for receptor binding. Infect. Immun. 68, 4566-4573.
-
(2000)
Infect. Immun
, vol.68
, pp. 4566-4573
-
-
Blöcker, D.1
Barth, H.2
Maier, E.3
Benz, R.4
Barbieri, J.T.5
Aktories, K.6
-
19
-
-
33751070013
-
Structure and action of the binary C2 toxin from Clostridium botulinum
-
Schleberger, C., Hochmann, H., Barth, H., Aktories, K., and Schulz, G. E. (2006) Structure and action of the binary C2 toxin from Clostridium botulinum. J. Mol. Biol. 364, 705-715.
-
(2006)
J. Mol. Biol
, vol.364
, pp. 705-715
-
-
Schleberger, C.1
Hochmann, H.2
Barth, H.3
Aktories, K.4
Schulz, G.E.5
-
20
-
-
0032491480
-
Characterization of the catalytic site of the ADP-ribosyltransferase Clostridium botulinum C2 toxin by site-directed mutagenesis
-
Barth, H., Preiss, J. C., Hofmann, F., and Aktories, K. (1998) Characterization of the catalytic site of the ADP-ribosyltransferase Clostridium botulinum C2 toxin by site-directed mutagenesis. J. Biol. Chem. 273, 29506-28511.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 29506-28511
-
-
Barth, H.1
Preiss, J.C.2
Hofmann, F.3
Aktories, K.4
-
21
-
-
0035815642
-
Low pH-induced formation of ion channels by Clostridium difficile toxin B in target cells
-
Barth, H., Pfeifer, G., Hofmann, F., Maier, E., Benz, R., and Aktories, K. (2001) Low pH-induced formation of ion channels by Clostridium difficile toxin B in target cells. J. Biol. Chem. 276, 10670-10676.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 10670-10676
-
-
Barth, H.1
Pfeifer, G.2
Hofmann, F.3
Maier, E.4
Benz, R.5
Aktories, K.6
-
22
-
-
0018139740
-
Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli
-
Benz, R., Janko, K., Boos, W., and Lauger, P. (1978) Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli. Biochim. Biophys. Acta 511, 305-319.
-
(1978)
Biochim. Biophys. Acta
, vol.511
, pp. 305-319
-
-
Benz, R.1
Janko, K.2
Boos, W.3
Lauger, P.4
-
23
-
-
23044508996
-
A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore
-
Krantz, B. A., Melnyk, R. A., Zhang, S., Juris, S. J., Lacy, D. B., Wu, Z., Finkelstein, A., and Collier, R. J. (2005) A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore. Science 309, 777-781.
-
(2005)
Science
, vol.309
, pp. 777-781
-
-
Krantz, B.A.1
Melnyk, R.A.2
Zhang, S.3
Juris, S.J.4
Lacy, D.B.5
Wu, Z.6
Finkelstein, A.7
Collier, R.J.8
-
24
-
-
0028286786
-
Interaction of Clostridium botulinum C2 toxin with lipid bilayer membranes: Formation of cation-selective channels and inhibition of channel function by chloroquine and peptides
-
Schmid, A., Benz, R., Just, I., and Aktories, K. (1994) Interaction of Clostridium botulinum C2 toxin with lipid bilayer membranes: formation of cation-selective channels and inhibition of channel function by chloroquine and peptides. J. Biol. Chem. 269, 16706-16711.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 16706-16711
-
-
Schmid, A.1
Benz, R.2
Just, I.3
Aktories, K.4
-
25
-
-
0035404038
-
Interaction of Clostridium botulinum C2-toxin with lipid bilayer membranes and Vero cells: Inhibition of channel function by chloroquine and related compounds in vitro and intoxification in vivo
-
Bachmeyer, C., Benz, R., Barth, H., Aktories, K., Gibert, M., and Popoff, M. (2001) Interaction of Clostridium botulinum C2-toxin with lipid bilayer membranes and Vero cells: inhibition of channel function by chloroquine and related compounds in vitro and intoxification in vivo. FASEB J. 15, 1658-1660.
-
(2001)
FASEB J
, vol.15
, pp. 1658-1660
-
-
Bachmeyer, C.1
Benz, R.2
Barth, H.3
Aktories, K.4
Gibert, M.5
Popoff, M.6
-
26
-
-
42949085407
-
Clostridium botulinum C2 toxin - identification of the binding site for chloroquine and related iompounds and influence of the binding site on properties of the C2II channel
-
Neumeyer, T., Schiffler, B., Maier, E., Lang, A. E., Aktories, K., and Benz, R. (2008) Clostridium botulinum C2 toxin - identification of the binding site for chloroquine and related iompounds and influence of the binding site on properties of the C2II channel, J. Biol. Chem. 283, 3904-3914.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 3904-3914
-
-
Neumeyer, T.1
Schiffler, B.2
Maier, E.3
Lang, A.E.4
Aktories, K.5
Benz, R.6
-
27
-
-
33745606447
-
A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation
-
Melnyk, R. A., and Collier, R. J. (2006) A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation. Proc. Natl. Acad. Sci. U.S.A. 103, 9802-9807.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 9802-9807
-
-
Melnyk, R.A.1
Collier, R.J.2
-
28
-
-
33847705768
-
Insertion of anthrax protective antigen into liposomal membranes: Effects of a receptor
-
Sun, J., Vernier, G., Wigelsworth, D. J., and Collier, R. J. (2007) Insertion of anthrax protective antigen into liposomal membranes: Effects of a receptor. J. Biol. Chem. 282, 1059-1065.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 1059-1065
-
-
Sun, J.1
Vernier, G.2
Wigelsworth, D.J.3
Collier, R.J.4
-
29
-
-
41949084238
-
Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation
-
Sun, J., Lang, A. E., Aktories, K., and Collier, R. J. (2008) Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation. Proc. Natl. Acad. Sci. U.S.A. 105, 4346-4351.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 4346-4351
-
-
Sun, J.1
Lang, A.E.2
Aktories, K.3
Collier, R.J.4
|